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anti-Mouse (Murine) IFNB1 antibody for Immunofluorescence

Recommended IFNB1 Antibody (supplied by: Log in to see )

Antigen
Interferon, beta 1, Fibroblast (IFNB1) Antibodies
  • IFB
  • Ifb
  • IFF
  • IFN-beta
  • IFN-R
  • IFN-R-2
  • IFNb
  • IFNB
  • Ifnb
  • IFNBR
Reactivity
Mouse (Murine)
229
28
15
15
11
7
7
5
5
3
1
1
1
Host
Goat
191
85
10
6
5
4
4
Clonality
Polyclonal
Conjugate
This IFNB1 antibody is un-conjugated
28
23
10
4
4
4
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
230
190
81
47
30
25
25
24
17
13
12
7
6
5
4
2
2
2
1
1
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Available images

Catalog No. ABIN2665499
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010850475 ABIN189808 FACS IHC (fro) IF FITC Rat IgG1 Log in to see RMMB-1

Top referenced anti-IFNB1 antibody for Immunofluorescence

Similar anti-IFNB1 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 14 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 3 Antibodies
Functional Studies (Func) 2 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 12 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 7 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Multiplex Assay (MA) 2 Antibodies
Neutralization (Neut) 3 Antibodies
Western Blotting (WB) 20 Antibodies

General

Antigen Interferon, beta 1, Fibroblast (IFNB1) Antibodies
Reactivity Mouse (Murine)
(229), (28), (15), (15), (11), (7), (7), (5), (5), (3), (1), (1), (1)
Host Goat
(191), (85), (10), (6), (5), (4), (4)
Clonality (Clone)
Polyclonal   ( )
Conjugate This IFNB1 antibody is un-conjugated
(28), (23), (10), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(230), (190), (81), (47), (30), (25), (25), (24), (17), (13), (12), (7), (6), (5), (4), (2), (2), (2), (1), (1)
Pubmed 2 references available
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Product Details anti-IFNB1 Antibody

Target Details IFNB1 Application Details Handling References for anti-IFNB1 Antibody (ABIN2665499) Images
Purification The antibody was purified by antigen-affinity chromatography.
Clone Poly5192
Isotype Ig Fraction

Target Details IFNB1

Product Details anti-IFNB1 Antibody Application Details Handling References for anti-IFNB1 Antibody (ABIN2665499) Images back to top
Antigen
Alternative Name IFN-beta (IFNB1 Antibody Abstract)
Background Interferon-β is a member of the type I interferon class. Type I IFNs are involved in the innate immune system, being released non-specifically during the early stage of infection in response to stimuli such as viruses, dsRNA, LPS, and bacterial components. Once secreted by virus-infected or activated cells, they bind to the IFNα/β receptor (IFNAR), which is found on almost all cell types, and, via the JAK-STAT pathway, induce the expression of hundreds of IFN-stimulated genes (ISGs). While the function of many of these proteins remains to be elucidated, a hallmark of type I IFNs is their anti-viral activities, both general and specific against particular viruses. Type I IFNs also regulate cell growth and apoptosis, and exert various immunomodulatory and inflammatory effects. As such, they are also clinically relevant, both as therapeutics and as targets of inhibition for the treatment of various autoimmune diseases and cancer. Mouse IFN-β is a ~20 kD monomeric glycoprotein. It has 50 % amino acid sequence homology with mouse IFN-α, its closest related protein, and 62 % homology with human IFN-β. IFN-β is currently the therapeutic of choice for treating multiple sclerosis.
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IFNB1 Antibody Target Details IFNB1 Handling References for anti-IFNB1 Antibody (ABIN2665499) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details References for anti-IFNB1 Antibody (ABIN2665499) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IFNB1 Antibody (ABIN2665499)

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details Handling Images back to top
Background publications

Nagarajan: "Induction and function of IFNβ during viral and bacterial infection." in: Critical reviews in immunology, Vol. 31, Issue 6, pp. 459-74, 2012

Honda, Yanai, Takaoka, Taniguchi: "Regulation of the type I IFN induction: a current view." in: International immunology, Vol. 17, Issue 11, pp. 1367-78, 2005

Images

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details Handling References for anti-IFNB1 Antibody (ABIN2665499) back to top
Supplier Images
ELISA image for anti-IFNB1 antibody (Interferon, beta 1, Fibroblast) (ABIN2665499) anti-Interferon, beta 1, Fibroblast (IFNB1) antibody