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anti-Mouse (Murine) IFNB1 antibody for Multiplex Assay

Recommended IFNB1 Antibody (supplied by: Log in to see )

Antigen
Interferon, beta 1, Fibroblast (IFNB1) Antibodies
  • IFB
  • Ifb
  • IFF
  • IFN-beta
  • IFN-R
  • IFN-R-2
  • IFNb
  • IFNB
  • Ifnb
  • IFNBR
Reactivity
Mouse (Murine)
303
29
15
15
11
7
7
5
5
3
1
1
1
Host
Hamster
192
158
10
6
6
4
3
Clonality
Monoclonal
Conjugate
This IFNB1 antibody is un-conjugated
32
27
14
8
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
Application
Multiplex Assay (MA)
305
264
84
49
32
26
25
24
17
14
12
8
7
5
4
2
2
1
1
1
Supplier
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Catalog No. ABIN2665793
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008696448 ABIN2665792 MA Hamster IgG Log in to see MIB-5E9-1 5

Top referenced anti-IFNB1 antibody for Multiplex Assay

Similar anti-IFNB1 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 15 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 3 Antibodies
Functional Studies (Func) 2 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 13 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Multiplex Assay (MA) 2 Antibodies
Neutralization (Neut) 3 Antibodies
Western Blotting (WB) 21 Antibodies

General

Antigen Interferon, beta 1, Fibroblast (IFNB1) Antibodies
Reactivity Mouse (Murine)
(303), (29), (15), (15), (11), (7), (7), (5), (5), (3), (1), (1), (1)
Host Hamster
(192), (158), (10), (6), (6), (4), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IFNB1 antibody is un-conjugated
(32), (27), (14), (8), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1)
Application Multiplex Assay (MA)
(305), (264), (84), (49), (32), (26), (25), (24), (17), (14), (12), (8), (7), (5), (4), (2), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-IFNB1 Antibody

Target Details IFNB1 Application Details Handling References for anti-IFNB1 Antibody (ABIN2665793) Images
Brand LEAF™
Purification The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Clone MIB-5E9-1
Isotype IgG

Target Details IFNB1

Product Details anti-IFNB1 Antibody Application Details Handling References for anti-IFNB1 Antibody (ABIN2665793) Images back to top
Antigen
Alternative Name IFN-beta (IFNB1 Antibody Abstract)
Background Interferon-β is a member of the type I interferon class. Type I IFNs are involved in the innate immune system, being released non-specifically during the early stage of infection in response to stimuli such as viruses, dsRNA, LPS, and bacterial components. Once secreted by virus-infected or activated cells, they bind to the IFNα/β receptor (IFNAR), which is found on almost all cell types, and, via the JAK-STAT pathway, induce the expression of hundreds of IFN-stimulated genes (ISGs). While the function of many of these proteins remains to be elucidated, a hallmark of type I IFNs is their anti-viral activities, both general and specific against particular viruses. Type I IFNs also regulate cell growth and apoptosis, and exert various immunomodulatory and inflammatory effects. As such, they are also clinically relevant, both as therapeutics and as targets of inhibition for the treatment of various autoimmune diseases and cancer. Mouse IFN-β is a ~20 kD monomeric glycoprotein. It has 50 % amino acid sequence homology with mouse IFN-α, its closest related protein, and 62 % homology with human IFN-β. IFN-β is currently the therapeutic of choice for treating multiple sclerosis.
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IFNB1 Antibody Target Details IFNB1 Handling References for anti-IFNB1 Antibody (ABIN2665793) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details References for anti-IFNB1 Antibody (ABIN2665793) Images back to top
Concentration 1.0 mg/mL
Preservative Azide free
Handling Advice This LEAF™ solution contains no preservative, handle under aseptic conditions
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IFNB1 Antibody (ABIN2665793)

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details Handling Images back to top
Background publications

Nagarajan: "Induction and function of IFNβ during viral and bacterial infection." in: Critical reviews in immunology, Vol. 31, Issue 6, pp. 459-74, 2012

Creasy, McCoy: "Cytokines regulate cysteine cathepsins during TLR responses." in: Cellular immunology, Vol. 267, Issue 1, pp. 56-66, 2011

Zaric, Coulter, Shelburne, Fulton, Zaric, Scott, Lappin, Fitzgerald, Irwin, Taggart: "Altered Toll-like receptor 2-mediated endotoxin tolerance is related to diminished interferon beta production." in: The Journal of biological chemistry, Vol. 286, Issue 34, pp. 29492-500, 2011

Sow, Alvarez, Gross, Satoskar, Schlesinger, Zwilling, Lafuse: "Role of STAT1, NF-kappaB, and C/EBPbeta in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-gamma." in: Journal of leukocyte biology, Vol. 86, Issue 5, pp. 1247-58, 2009

Honda, Yanai, Takaoka, Taniguchi: "Regulation of the type I IFN induction: a current view." in: International immunology, Vol. 17, Issue 11, pp. 1367-78, 2005