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anti-Rat (Rattus) IFNB1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended IFNB1 Antibody (supplied by: Log in to see )

Antigen
Interferon, beta 1, Fibroblast (IFNB1) Antibodies
  • IFB
  • Ifb
  • IFF
  • IFN-beta
  • IFN-R
  • IFN-R-2
  • IFNb
  • IFNB
  • Ifnb
  • IFNBR
Reactivity
Mouse (Murine), Rat (Rattus)
229
28
15
14
11
7
7
5
5
3
1
1
1
Host
Rabbit
190
85
10
6
6
4
4
Clonality
Polyclonal
Conjugate
This IFNB1 antibody is un-conjugated
28
23
10
4
4
4
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
230
190
82
48
29
26
25
24
17
13
11
7
7
5
4
2
2
2
1
1
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Available images

Catalog No. ABIN728113
$ 269.50
Plus shipping costs $45.00

Similar anti-IFNB1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 10 Antibodies 14 Antibodies
Functional Studies (Func) 1 Antibodies 2 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 2 Antibodies 12 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antibodies
Neutralization (Neut) 1 Antibodies
Western Blotting (WB) 12 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 3 Antibodies
Immunofluorescence (IF) 2 Antibodies

General

Antigen Interferon, beta 1, Fibroblast (IFNB1) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(229), (28), (15), (14), (11), (7), (7), (5), (5), (3), (1), (1), (1)
Host Rabbit
(190), (85), (10), (6), (6), (4), (4)
Clonality
Polyclonal
Conjugate This IFNB1 antibody is un-conjugated
(28), (23), (10), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(230), (190), (82), (48), (29), (26), (25), (24), (17), (13), (11), (7), (7), (5), (4), (2), (2), (2), (1), (1)
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Product Details anti-IFNB1 Antibody

Target Details IFNB1 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse IFN-beta
Isotype IgG

Target Details IFNB1

Product Details anti-IFNB1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name IFN-beta (IFNB1 Antibody Abstract)
Background

The mammalian type I Inteferons (IFN1) are produced in response to viral infection and other inducers. They are divided into alpha and beta subtypes leukocytes and fibroblasts reactivity. The human IFN alphas are encoded by a family of at least 15 different genes, while IFN beta is the unique member of its subtype. There is approximately 50 % amino acid homology between the alpha and beta subtypes. Both IFN subtypes are pleiotropic cytokines and have a similar range of biological activities. Differences between alpha subtypes, and between IFN alpha and betas, are in potency and cell type specific activities. In particular, IFN beta elicits a markedly higher antiproliferation response in some cell types such as, embryonal carcinoma, melanoma and melanocytes than do IFN alphas. Higher potency of IFN beta in treatment of multiple sclerosis and certain cancers has been observed. Type I IFNs signal through binding to a common cell surface receptor. Two chains of the receptor, IFNAR1 and IFNAR2, have been identified. Both chains are necessary for function and in the absence of either there is neither high affinity binding nor biological activity. The intracellular portions of the receptor subunits are bound by tyrosine kinases, Jak1 and Tyk2, members of the Janus kinase family. Upon ligand binding these kinases are activated and phosphorylate members of the STAT family of transcription factors, as well as IFNAR1 and 2.


Synonyms: Fibroblast interferon, N-Beta, N i², i²-N, B, i² N, i²N, F, N beta, NB 1, NB , NB1, Interferon beta 1 fibroblast , Beta-N, Beta N, Interferon beta precursor, MGC96956i1/4> Interferon betai1/4> Interferon-beta.
Gene ID 24481
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IFNB1 Antibody Target Details IFNB1 Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-IFNB1 Antibody Target Details IFNB1 Application Details Handling back to top
Supplier Images
ELISA image for anti-IFNB1 antibody (Interferon, beta 1, Fibroblast) (ABIN728113) Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:...