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|Antigen||Interleukin 13 (IL13) Antibodies|
|Epitope||AA 36-146 Alternatives|
|Conjugate||This IL-13 antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-IL-13 AntibodyTarget Details IL-13 Application Details Handling Images
|Purpose||Rabbit IgG polyclonal antibody for Interleukin-13(IL13) detection. Tested with WB, IHC-P in Human.|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Interleukin-13(IL13) detection. Tested with WB, IHC-P in Human.
Gene Name: interleukin 13
Protein Name: Interleukin-13
|Purification||Immunogen affinity purified.|
|Immunogen||E. coli-derived human IL13 recombinant protein (Position: P36-N146). Human IL13 shares 55.3% and 61.9% amino acid (aa) sequence identity with mouse and rat IL13, respectively.|
Target Details IL-13Product Details anti-IL-13 Antibody Application Details Handling Images back to top
|Alternative Name||IL13 (IL13 Antibody Abstract)|
Interleukin 13 is a protein that in humans is encoded by the IL-13 gene. It is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. Furthermore, this gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.
Synonyms: ALRH | IL 13 | IL13 | IL-13 | il13ra2 | interleukin 13 | Interleukin13 | Interleukin-13 | Interleukin13(IL13) | Interleukin-13(IL-13) | NC30
|Research Area||Cytokines, Innate Immunity, Cancer|
|Pathways||JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport|
Application DetailsProduct Details anti-IL-13 Antibody Target Details IL-13 Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL-13 Antibody Target Details IL-13 Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C,-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.