anti-Human IL-6 Receptor antibody for Functional Studies

Recommended IL-6 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin-6 Receptor (IL6R) Antibodies
  • IL6R
  • il-6ra
  • CD126
  • IL-6R-1
  • IL-6RA
  • IL6Q
  • IL6RA
  • IL6RQ
  • gp80
  • IL6R1
  • Il6ra
  • IL-6Ralpha
  • IL-6R
  • Il6r
  • interleukin 6 receptor
  • interleukin 6 receptor-like
  • interleukin 6 receptor, alpha
  • IL6R
  • il6r
  • Il6r
  • LOC100347752
  • Il6ra
Reactivity
Human
182
97
46
1
Host
Mouse
130
93
52
23
2
Clonality
Monoclonal
Conjugate
This IL-6 Receptor antibody is un-conjugated
26
15
15
10
10
9
7
7
5
5
5
5
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunoprecipitation (IP)
132
127
103
71
39
24
24
21
17
13
10
10
9
8
7
6
4
2
2
2
2
2
1
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Catalog No. ABIN1105829
$ 308.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1105827 Func EIA IHC (fro) FACS Mouse IgG1 Log in to see B-F19 2
1 ABIN208783 Func FACS Neut Mouse IgG1 Log in to see B-R6
1 ABIN2877896 Func FACS IHC (fro) IP ELISA Mouse IgG1 Log in to see B-R6
1 ABIN233222 Func FACS Biotin Mouse IgG1 Log in to see
1 ABIN1722533 Func IHC (fro) FACS IP ELISA Mouse IgG1 Log in to see B-R6
1 ABIN1722534 Func FACS IHC ELISA Mouse IgG1 Log in to see B-F19

General

Antigen Interleukin-6 Receptor (IL6R) Antibodies
Reactivity Human
(182), (97), (46), (1)
Host Mouse
(130), (93), (52), (23), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL-6 Receptor antibody is un-conjugated
(26), (15), (15), (10), (10), (9), (7), (7), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunoprecipitation (IP)
(132), (127), (103), (71), (39), (24), (24), (21), (17), (13), (10), (10), (9), (8), (7), (6), (4), (2), (2), (2), (2), (2), (1)
Pubmed 3 references available
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Product Details anti-IL-6 Receptor Antibody

Target Details IL-6 Receptor Application Details Handling ProductDetails: References for anti-IL-6 Receptor antibody (ABIN1105829) Images
Specificity This antibody recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein.Aff. Const.:Kd: 1.22 mM
Purification Ion exchange chromatography
Sterility 0.22 μm filtered
Immunogen gp80 transfected CHO cell line
Clone B-R6
Isotype IgG1

Target Details IL-6 Receptor

Product Details anti-IL-6 Receptor Antibody Application Details Handling ProductDetails: References for anti-IL-6 Receptor antibody (ABIN1105829) Images back to top
Antigen
Alternative Name CD126 / IL6R (IL6R Antibody Abstract)
Background Synonyms: IL-6R 1, IL-6R-alpha, IL6 Receptor alpha, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80
Gene ID 3570
NCBI Accession NP_000556
UniProt P08887
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways JAK-STAT Signaling, Autophagy, Growth Factor Binding

Application Details

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Handling ProductDetails: References for anti-IL-6 Receptor antibody (ABIN1105829) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details ProductDetails: References for anti-IL-6 Receptor antibody (ABIN1105829) Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate-buffered saline. Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free
Preservative Without preservative
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

ProductDetails: References for anti-IL-6 Receptor antibody (ABIN1105829)

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling Images back to top
Background publications

Burger, Guenther, Bakker, Schmalzing, Bernand, Baum, Duerr, Hocke, Steininger, Gebhart, Gramatzki: "Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma." in: The hematology journal : the official journal of the European Haematology Association / EHA, Vol. 2, Issue 1, pp. 42-53, 2002

Dubois, Barthélémy, Durand, Liu, Caux, Brière: "Toward a role of dendritic cells in the germinal center reaction: triggering of B cell proliferation and isotype switching." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 6, pp. 3428-36, 1999

Dubois, Massacrier, Vanbervliet, Fayette, Brière, Banchereau, Caux: "Critical role of IL-12 in dendritic cell-induced differentiation of naive B lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 5, pp. 2223-31, 1998

Images

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling ProductDetails: References for anti-IL-6 Receptor antibody (ABIN1105829) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Interleukin-6 Receptor (IL6R) antibody (ABIN1105829) anti-Interleukin-6 Receptor (IL6R) antibody