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anti-Human IL-6 Receptor antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended IL-6 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin-6 Receptor (IL6R) Antibodies
  • CD126
  • gp80
  • IL-6R
  • IL-6R-1
  • IL-6RA
  • il-6ra
  • IL-6Ralpha
  • IL6Q
  • Il6r
  • IL6R
  • IL6R1
  • IL6RA
  • Il6ra
  • IL6RQ
Reactivity
Human
129
58
43
Host
Rabbit
85
83
23
15
1
Clonality
Polyclonal
Conjugate
This IL-6 Receptor antibody is un-conjugated
22
14
11
10
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
86
75
73
27
22
14
12
11
11
11
10
9
8
6
3
2
2
1
1
1
1
Supplier
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Available images

Catalog No. ABIN951184
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN959335 IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
0.00089488085 ABIN1735900 IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
0.00089488085 ABIN1175051 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 216-356 Log in to see Polyclonal
0.00089488085 ABIN2764391 IHC (p) IHC ELISA WB Rabbit IgG Log in to see Polyclonal

Similar anti-IL-6 Receptor Antibodies

Application / Reactivity Human
ELISA 60 Antibodies
ELISA (Capture) 2 Antibodies
ELISA (Detection) 1 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 60 Antibodies
Functional Studies (Func) 8 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 9 Antibodies
Immunohistochemistry (IHC) 22 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 14 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Immunoprecipitation (IP) 13 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies
Mass Cytometry (CyTOF) 1 Antibodies
Neutralization (Neut) 10 Antibodies
Western Blotting (WB) 48 Antibodies

General

Antigen Interleukin-6 Receptor (IL6R) Antibodies
Reactivity Human
(129), (58), (43)
Host Rabbit
(85), (83), (23), (15), (1)
Clonality
Polyclonal
Conjugate This IL-6 Receptor antibody is un-conjugated
(22), (14), (11), (10), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(86), (75), (73), (27), (22), (14), (12), (11), (11), (11), (10), (9), (8), (6), (3), (2), (2), (1), (1), (1), (1)
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Product Details anti-IL-6 Receptor Antibody

Target Details IL-6 Receptor Application Details Handling Images
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity Chromatography
Immunogen Synthetic peptide
Isotype IgG

Target Details IL-6 Receptor

Product Details anti-IL-6 Receptor Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD126 / IL6R (IL6R Antibody Abstract)
Background IL6 exerts its activity through binding to a high affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa IL6 binding receptor protein (IL6R) and a 130 kDa signal transducing protein consisting of a 19 amino acid residue signal peptide (gp130). Human IL6R is a 468 amino acid residue type I membrane protein consisting of a 19 amino acid residue signal peptide, a 339 residue extracellular region, a 28 residue transmembrane region and an 82 residue cytoplasmic region. The ectodomain of IL6R is made up of an immunoglobulin like domain and a cytokine receptor superfamily domain. A naturally occurring soluble form of the IL6R, which binds IL6 and which mediates IL6 signaling through interaction with gp130, is identified in the urine of healthy adult humans. It has also been detected in human and mouse serum as well as in the conditioned medium of various cells including human peripheral blood mononuclear cells, and several T cell or granulocyte/macrophage cell lines. Increased expression of the c-fos and c-myc protooncogenes have been linked to IL6 receptor activation.Synonyms: IL-6R 1, IL-6R-alpha, IL6 Receptor alpha, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80
Gene ID 3570
NCBI Accession NP_000556
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-IL-6 Receptor antibody (Interleukin-6 Receptor) (ABIN951184) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western Blotting (WB) image for anti-IL-6 Receptor antibody (Interleukin-6 Receptor) (ABIN951184) Western Blot analysis of Jurkat and 803 cell lysates with anti-IL6R antibody at 1/200...