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anti-Mouse (Murine) IL12B antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended IL12B Antibody (supplied by: Log in to see )

Antigen
Interleukin 12b (IL12B) Antibodies
  • IL-12B
  • IL12B
  • p40
  • Il-12b
  • Il12p40
  • Il-12p40
  • Il12
  • CLMF
  • CLMF2
  • NKSF
  • NKSF2
  • IL12p40
  • IL-12
  • IL-12.p40
  • IL-12p40
  • interleukin 12 p40 subunit
  • interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • interleukin 12b
  • interleukin 12B
  • interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
  • IL-12
  • IL12A
  • Il12b
  • IL12B
Epitope
AA 220-255
24
19
13
12
11
10
7
6
5
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
147
60
26
25
22
4
2
2
1
1
1
Host
Rabbit
134
58
34
10
4
1
1
Clonality
Polyclonal
Conjugate
This IL12B antibody is un-conjugated
19
16
15
8
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
164
152
64
25
22
16
9
6
6
5
4
3
3
2
1
1
1
1
1
Options
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Catalog No. ABIN2176964
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5519010 ELISA IHC (p) WB Rabbit IgG AA 23-250 Log in to see Polyclonal
1 ABIN2176966 IHC (p) WB HRP Rabbit IgG AA 220-255 Log in to see Polyclonal
1 ABIN2176965 IHC (p) WB Biotin Rabbit IgG AA 220-255 Log in to see Polyclonal

Top referenced anti-IL12B antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-IL12B Antibodies

Application / Reactivity Mouse (Murine) Rat (Rattus) Human
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 1 Antibodies
Western Blotting (WB) 97 Antibodies 46 Antibodies 21 Antibodies
Neutralization (Neut) 3 Antibodies 2 Antibodies
Immunoprecipitation (IP) 4 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies 5 Antibodies 4 Antibodies
Immunohistochemistry (IHC) 49 Antibodies 4 Antibodies 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 22 Antibodies

General

Antigen Interleukin 12b (IL12B) Antibodies
Epitope AA 220-255
(24), (19), (13), (12), (11), (10), (7), (6), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(147), (60), (26), (25), (22), (4), (2), (2), (1), (1), (1)
Host Rabbit
(134), (58), (34), (10), (4), (1), (1)
Clonality
Polyclonal
Conjugate This IL12B antibody is un-conjugated
(19), (16), (15), (8), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(164), (152), (64), (25), (22), (16), (9), (6), (6), (5), (4), (3), (3), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-IL12B Antibody

Target Details IL12B Application Details Handling References for anti-IL12B Antibody (ABIN2176964) Images
Purification Purified by Protein A.
Isotype IgG

Target Details IL12B

Product Details anti-IL12B Antibody Application Details Handling References for anti-IL12B Antibody (ABIN2176964) Images back to top
Antigen
Alternative Name IL-12 beta (IL12B Antibody Abstract)
Background

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Subcellular location: Secreted


Synonyms: CLMF, NKSF, CLMF2, IMD28, IMD29, NKSF2, IL-12B, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40, NK cell stimulatory factor chain 2, IL12B
Gene ID 3593
UniProt P29460
Pathways JAK-STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation

Application Details

Product Details anti-IL12B Antibody Target Details IL12B Handling References for anti-IL12B Antibody (ABIN2176964) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only

Handling

Product Details anti-IL12B Antibody Target Details IL12B Application Details References for anti-IL12B Antibody (ABIN2176964) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-IL12B Antibody (ABIN2176964)

Product Details anti-IL12B Antibody Target Details IL12B Application Details Handling Images back to top
Product cited in:

Li, Dan, Nie, Hu, Gesang, Bianba, Ze, Ciren: "CD14 knockdown reduces lipopolysaccharide-induced cell viability and expression of inflammation-associated genes in gastric cancer cells in vitro and in nude mouse xenografts." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 4332-9, 2015

Images

Product Details anti-IL12B Antibody Target Details IL12B Application Details Handling References for anti-IL12B Antibody (ABIN2176964) back to top
Supplier Images
Western Blotting (WB) image for anti-IL12B antibody (Interleukin 12b) (AA 220-255) (ABIN2176964) Mouse spleen lysates probed with Rabbit Anti-IL-12 beta Polyclonal Antibody, Unconjug...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-IL12B antibody (Interleukin 12b) (AA 220-255) (ABIN2176964) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-IL-12 bet...