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|Antigen||Interleukin 12b (IL12B) Antibodies|
|Epitope||AA 23-321 Alternatives|
|Reactivity||Rat (Rattus) Alternatives|
|Conjugate||This IL12B antibody is un-conjugated Alternatives|
Western Blotting (WB)
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Product Details anti-IL12B AntibodyTarget Details IL12B Application Details Handling Images
|Purpose||Rabbit IgG polyclonal antibody for Interleukin-12 subunit beta(IL12B) detection. Tested with WB in Rat.|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Interleukin-12 subunit beta(IL12B) detection. Tested with WB in Rat.
Gene Name: interleukin 12B
Protein Name: Interleukin-12 subunit beta
|Purification||Immunogen affinity purified.|
|Immunogen||E.coli-derived rat IL-12(p40) recombinant protein (Position: M23-S321).|
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|Alternative Name||IL12B (IL12B Antibody Abstract)|
Subunit beta of interleukin 12, also known as interleukin 12B, or IL12B, is a subunit of human interleukin 12. It is mapped to 5q33.3. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease.
Synonyms: 40 kD Subunit antibody|CLMF 2 antibody|CLMF antibody|CLMF p40 antibody|CLMF2 antibody|Cytotoxic lymphocyte maturation factor 2 antibody|Cytotoxic lymphocyte maturation factor 2 p40 antibody|Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody|IL 12 subunit p40 antibody|IL 12B antibody|IL-12 subunit p40 antibody|IL-12B antibody|IL12 subunit p40 antibody|IL12B antibody|IL12B_HUMAN antibody|Interleukin 12 beta chain antibody|Interleukin 12 p40 antibody|Interleukin 12 subunit beta antibody|Interleukin 12B antibody|Interleukin-12 subunit beta antibody|Natural killer cell stimulatory factor 2 antibody|natural killer cell stimulatory factor 40 kD subunit antibody|NK cell stimulatory factor chain 2 antibody|NKSF 2 antibody|NKSF antibody|NKSF2 antibody|p40 antibody|TcMF antibody|TSF antibody
|Research Area||Hormones, Cytokines|
|Pathways||JAK-STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation|
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, The detection limit for IL-12(p40) is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
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|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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