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|Antigen||Interleukin 12b (IL12B) Antibodies|
|Reactivity||Sheep (Ovine) Alternatives|
|Conjugate||This IL12B antibody is conjugated to HRP Alternatives|
ELISA, Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-IL12B AntibodyTarget Details IL12B Application Details Handling Images
|Purification||Caprylic Acid Ammonium Sulfate Precipitation|
|Immunogen||Recombinant Sheep Interleukin-12 subunit beta protein|
Target Details IL12BProduct Details anti-IL12B Antibody Application Details Handling Images back to top
|Alternative Name||Interleukin-12 subunit beta (IL12B Antibody Abstract)|
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC By similarity.Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis By similarity.
Synonyms: Cytotoxic lymphocyte maturation factor 40 kDa subunit,IL-12 subunit p40,IL12B
Application DetailsProduct Details anti-IL12B Antibody Target Details IL12B Handling Images back to top
|Application Notes||Optimal working concentration should be determinde by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL12B Antibody Target Details IL12B Application Details Images back to top
|Buffer||0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4|
|Precaution of Use||This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
|Storage||-20 °C/-80 °C|
|Storage Comment||Upon delivery aliquot and store at -20 °C or -80 °C.|