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Browse our IL12B (IL12B) ELISA Kits

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Interleukin 12b ELISA Kits (IL12B)
On are 88 Interleukin 12b (IL12B) ELISA Kits from 17 different suppliers available. Additionally we are shipping IL12B Antibodies (222) and IL12B Proteins (69) and many more products for this protein. A total of 409 IL12B products are currently listed.
CLMF, CLMF2, IL-12, IL-12.p40, Il-12b, IL-12p40, Il12, IL12B, IL12p40, NKSF, NKSF2, p40
list all ELISA KIts Gene Name GeneID UniProt
IL12B 16160 P43432
IL12B 64546  
IL12B 3593 P29460

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Top referenced IL12B ELISA Kits

  1. Human IL12B ELISA Kit for Sandwich ELISA - ABIN411311 : Becher, Durell, Noelle: Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12. in The Journal of clinical investigation 2002 (PubMed)
    Show all 8 references for ABIN411311

  2. Mouse (Murine) IL12B ELISA Kit for Sandwich ELISA - ABIN1672845 : Cua, Sherlock, Chen, Murphy, Joyce, Seymour, Lucian, To, Kwan, Churakova, Zurawski, Wiekowski, Lira, Gorman, Kastelein, Sedgwick: Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. in Nature 2003 (PubMed)
    Show all 5 references for ABIN1672845

  3. Horse (Equine) IL12B ELISA Kit for Sandwich ELISA - ABIN416683 : Duran, Willenbrock, Müller, Nolte, Feige, Murua Escobar: Establishment and evaluation of a bead-based luminex assay allowing simultaneous quantification of equine IL-12 and IFN-?. in Anticancer research 2013 (PubMed)

More ELISA Kits for IL12B Interaction Partners

Mouse (Murine) Interleukin 12b (IL12B) interaction partners

  1. Irradiation-induced IL-6 (show IL6 ELISA Kits) can decrease IL-12 (show IL12A ELISA Kits) production through the inhibition of C-Rel (show NFkBP65 ELISA Kits) phosphorylation by the IL-6 (show IL6 ELISA Kits)/STAT3 (show STAT3 ELISA Kits) signaling pathway.

  2. The IL-12 (show IL12A ELISA Kits) response by dendritic cells against S. aureus is highly growth phase dependent.

  3. the PI3K pathway mediated IL-12 (show IL12A ELISA Kits) inhibition but did not interfere with the inhibition of IL-23 (show IL23A ELISA Kits) or stimulation of IL-10 (show IL10 ELISA Kits).

  4. Data indicate that sera from treated with cholesterol-p40 (Il12b)-siRNA contained significantly reduced concentrations of p40.

  5. this study demonstrates viral RNA analog-induced transcription synergy of Il6 (show IL6 ELISA Kits) and Il12b via IFN regulatory factor (IRF)1 (show IRF1 ELISA Kits) (TLR3 (show TLR3 ELISA Kits)-TIR domain-containing adaptor inducing IFN-beta (show TICAM1 ELISA Kits) [TRIF (show RNF138 ELISA Kits)] responsive), C/EBPbeta (show CEBPB ELISA Kits) (TLR7 (show TLR7 ELISA Kits)-MyD88 (show MYD88 ELISA Kits) responsive), and JunB (show JUNB ELISA Kits) (all responsive).

  6. These findings reveal a critical role for IL-12 (show IL12A ELISA Kits) in shaping the anti-inflammatory biofilm milieu by promoting MDSC recruitment.

  7. our results suggest that IL-12p40 acts as a negative regulator of autoimmune cholangitis in IL-2Ralpha-/- mice. Compared to IL-2Ralpha-/- mice, p40-/-IL-2Ralpha-/- mice develop liver fibrosis and reduced colitis.

  8. The systemic IL-10 (show IL10 ELISA Kits)/IL-12 (show IL12A ELISA Kits) axis is skewed after burn injury with infection as indicated by a significant elevation in serum IL-10 (show IL10 ELISA Kits) and polarization of neutrophils into an anti-inflammatory IL-12 (show IL12A ELISA Kits)-negative phenotype.

  9. the assembled p40 (show LANCL1 ELISA Kits)-CD5L (show CD5L ELISA Kits) heterodimer does not recapitulate the biological activity of IL-12 (show IL12A ELISA Kits).

  10. The immune-enhancing effect of the Cronobacter sakazakii ES2 (show DGCR14 ELISA Kits) phage results in the activation of nuclear factor-kappaB and dendritic cell maturation via the activation of IL-12p40 in the mouse bone marrow.

Human Interleukin 12b (IL12B) interaction partners

  1. the IL-12B rs3212227 AC and AC+CC genotypes are associated with rheumatoid arthritis risk in older patients,rheumatoid factor positive patients and anti-cyclic peptide antibodies negative patients

  2. High serum IL-12 (show IL12A ELISA Kits) levels associated with increased densities of peritumoral CD8 (show CD8A ELISA Kits)(+) T cells, intraepithelial CD3 (show CD3 ELISA Kits)(+) T cells and intratumoral neutrophils, while high serum CCL4 (show CCL4 ELISA Kits) levels associated with increased densities of peritumoral CD68 (show CD68 ELISA Kits)(+) cells

  3. Human IL-21 (show IL17C ELISA Kits)+IFN-gamma (show IFNG ELISA Kits)+CD4 (show CD4 ELISA Kits)+ T cells in nasal polyps are regulated by IL-12 (show IL12A ELISA Kits).

  4. No association was observed for IL-12B and IFN-gamma (show IFNG ELISA Kits) polymorphisms between the rheumatoid arthritis patients and controls.

  5. These observations indicate a HDAC1 (show HDAC1 ELISA Kits)-mediated IL-12B gene expression suppression by live, virulent Mycobacterium tuberculosis to subvert the immune system to survive and replicate in the host.

  6. Peripheral blood mononuclear cells from severe asthmatic children release lower amounts of IL-12 (show IL12A ELISA Kits) and IL-4 (show IL4 ELISA Kits) after LPS (show IRF6 ELISA Kits) stimulation.

  7. Findings demonstrate that IL-12 (show IL12A ELISA Kits) is increased significantly in chronic hepatitis B patients and that viral protein HBx induces IL-12 (show IL12A ELISA Kits) expression in hepatocytes through the activation of the PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) pathway.

  8. 8 SNPs (rs10045431, rs11167764, rs3212227, rs6556412, rs6556416, rs6871626, rs6887695 and rs7709212) were genotyped in Han ankylosing spondylitis patients and controls. rs6871626 may be associated AS susceptibility and activity.

  9. Gene-gene interaction analysis showed that subjects carrying the IL-12A (show IL12A ELISA Kits) rs568408AG/AA and IL-12B rs3212227AA genotypes had a 2.40-fold increased risk of CRC (show CALR ELISA Kits) (OR = 2.40; 95 % CI, 1.14-5.07)

  10. Findings suggest that the interleukin 12B (IL-12B) and interleukin 10 (IL-10 (show IL10 ELISA Kits))-592 genotypes were distributed homogenously across all major ethnic groups, including Malays, Chinese, and Indians.

Cow (Bovine) Interleukin 12b (IL12B) interaction partners

  1. The results showed that the expression of TNF-alpha (show TNF ELISA Kits), iNOS (show NOS2 ELISA Kits), and IL-6 (show IL6 ELISA Kits) in alveolar macrophages was up-regulated by stimulation with the recombinant Mce4A protein of M. bovis; in contrast, expression of IL-12 (show IL12A ELISA Kits) was unaffected.[IL-6 (show IL6 ELISA Kits), IL-12 (show IL12A ELISA Kits)]

  2. study investigated hypothesis that CD40 (show CD40 ELISA Kits) signalling is impaired in Mycobacterium avium subspecies paratuberculosis(MAP)-infected macrophages; propose that MAP interferes with gene expression of iNOS (show NOS2 ELISA Kits) and IL-12p40 genes downstream of p38 (show MAPK14 ELISA Kits)

Rhesus Monkey Interleukin 12b (IL12B) interaction partners

  1. In rhesus macaques plasmacytoid dendritic cells in peripheral blood express IL-12p40 upon TLR-7 (show TLR7 ELISA Kits)/8 and TLR-9 (show TLR9 ELISA Kits) stimulation, which could potentially affect their response to vaccination and viral infection.

Pig (Porcine) Interleukin 12b (IL12B) interaction partners

  1. Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (show TNF ELISA Kits), IL-6 (show IL6 ELISA Kits), IL-12p40, IL-1beta (show IL1B ELISA Kits), and resulted in increased expression of the apoptosis initiator caspase-8 (show CASP8 ELISA Kits) and bcl2L1 (show BCL2L1 ELISA Kits).

IL12B Antigen Profile

Antigen Summary

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.

Alternative names and synonyms associated with IL12B

  • interleukin 12 p40 subunit (IL-12) Elisa Kit
  • interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A) Elisa Kit
  • interleukin 12b (Il12b) Elisa Kit
  • interleukin 12B (Il12b) Elisa Kit
  • interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (IL12B) Elisa Kit
  • CLMF Elisa Kit
  • CLMF2 Elisa Kit
  • IL-12 Elisa Kit
  • IL-12.p40 Elisa Kit
  • Il-12b Elisa Kit
  • IL-12p40 Elisa Kit
  • Il12 Elisa Kit
  • IL12B Elisa Kit
  • IL12p40 Elisa Kit
  • NKSF Elisa Kit
  • NKSF2 Elisa Kit
  • p40 Elisa Kit

Protein level used designations for Interleukin 12b (IL12B) ELISA Kits

CLMF p40 , Cytotoxic lymphocyte maturation factor 40 kDa subunit , IL-12 subunit p40 , Interleukin-12 subunit beta , CLMF p35 , IL-12 subunit p35 , IL-12A , cytotoxic lymphocyte maturation factor 35 kDa subunit , interleukin 12B , interleukin-12 p35 subunit , interleukin-12 subunit alpha , IL-12 p40 , IL-23 subunit p40 , cytotoxic lymphocyte maturation factor 40 kDa subunit , interleukin-12 subunit beta , interleukin-12 p40 , IL-12B , interleukin-12 p40 subunit , IL12, subunit p40 , NK cell stimulatory factor chain 2 , interleukin 12, p40 , interleukin-12 beta chain , natural killer cell stimulatory factor, 40 kD subunit , interleukin 12 40kDa subunit , interleukin 12 p40 subunit , interleukin-12 p40 chain , IL-12 p40 subunit , interleukin-12p40

100860845 Capra hircus
403977 Canis lupus familiaris
16160 Mus musculus
64546 Rattus norvegicus
100135554 Cavia porcellus
3593 Homo sapiens
281857 Bos taurus
443472 Ovis aries
403976 Canis lupus familiaris
100034222 Equus caballus
768273 Felis catus
694747 Macaca mulatta
404671 Gallus gallus
397076 Sus scrofa
Selected quality suppliers for IL12B (IL12B) ELISA Kits
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