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anti-Human IL13 Receptor alpha 1 antibody for Cell-ELISA

Recommended IL13 Receptor alpha 1 Antibody (supplied by: Log in to see )

Antigen
Interleukin 13 Receptor, alpha 1 (IL13RA1) Antibodies
  • AI882074
  • CD213a1
  • CD213A1
  • IL-13Ra
  • il-13ra1
  • IL-13r[a]
  • Il13ra
  • IL13RA1
  • NR4
  • si:ch211-150g2.2
Epitope
Extracellular Domain
18
15
5
5
5
5
5
4
4
3
3
2
2
2
2
1
1
1
1
Reactivity
Human
78
24
5
4
Host
Mouse
71
18
1
Clonality
Monoclonal
Conjugate
This IL13 Receptor alpha 1 antibody is un-conjugated
10
5
4
3
2
2
1
Application
Antagonist (Anta), Cell-ELISA (cELISA), Flow Cytometry (FACS), ELISA
60
46
13
13
9
9
7
6
2
2
1
1
Supplier
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Catalog No. ABIN108718
$ 358.05
Plus shipping costs $45.00

Top referenced anti-IL13 Receptor alpha 1 antibody for Cell-ELISA

Similar anti-IL13 Receptor alpha 1 Antibodies

Application / Reactivity Human
Antagonist (Anta) 1 Antibodies
Cell-ELISA (cELISA) 1 Antibodies
ELISA 39 Antibodies
Flow Cytometry (FACS) 9 Antibodies
Functional Studies (Func) 1 Antibodies
Immunocytochemistry (ICC) 6 Antibodies
Immunofluorescence (IF) 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 13 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 57 Antibodies

General

Antigen Interleukin 13 Receptor, alpha 1 (IL13RA1) Antibodies
Epitope Extracellular Domain
(18), (15), (5), (5), (5), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human
(78), (24), (5), (4)
Host Mouse
(71), (18), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL13 Receptor alpha 1 antibody is un-conjugated
(10), (5), (4), (3), (2), (2), (1)
Application Antagonist (Anta), Cell-ELISA (cELISA), Flow Cytometry (FACS), ELISA
(60), (46), (13), (13), (9), (9), (7), (6), (2), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-IL13 Receptor alpha 1 Antibody

Target Details IL13 Receptor alpha 1 Application Details Handling References for anti-IL13 Receptor alpha 1 Antibody (ABIN108718) Images
Specificity GM1E7 recognises IL-13Ralpha1 transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on monocytes (Myrtek et al., 2004).
Purification Protein G
Immunogen genetic immunisation with cDNA encoding human IL13-Ralpha1 (extracellular domain)
Clone GM-1E7
Isotype IgG1

Target Details IL13 Receptor alpha 1

Product Details anti-IL13 Receptor alpha 1 Antibody Application Details Handling References for anti-IL13 Receptor alpha 1 Antibody (ABIN108718) Images back to top
Antigen
Alternative Name IL13Ra1 (IL13RA1 Antibody Abstract)
Background Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Rα1 together with IL-4Rα forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation.
UniProt P78552
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Handling References for anti-IL13 Receptor alpha 1 Antibody (ABIN108718) Images back to top
Application Notes Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.
Restrictions For Research Use only

Handling

Product Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Application Details References for anti-IL13 Receptor alpha 1 Antibody (ABIN108718) Images back to top
Buffer PBS, pH 7.2
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C
Storage Comment short term: 2 °C - 8 °C, long term: -20 °C

References for anti-IL13 Receptor alpha 1 Antibody (ABIN108718)

Product Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Application Details Handling Images back to top
Background publications

Natoli, Lüpertz, Merz, Müller, Köhler, Krammer, Li-Weber: "Targeting the IL-4/IL-13 signaling pathway sensitizes Hodgkin lymphoma cells to chemotherapeutic drugs." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 8, pp. 1945-54, 2013

Krause, Behrends, Borowski, Lohrmann, Lang, Myrtek, Lorenzen, Virchow, Luttmann, Friedrich: "Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor alpha1." in: Molecular immunology, Vol. 43, Issue 11, pp. 1799-807, 2006

Myrtek, Knoll, Matthiesen, Krause, Lohrmann, Schillinger, Idzko, Virchow, Friedrich, Luttmann: "Expression of interleukin-13 receptor alpha 1-subunit on peripheral blood eosinophils is regulated by cytokines." in: Immunology, Vol. 112, Issue 4, pp. 597-604, 2004

Ahotupa, Mäntylä, Peltola, Puntala, Toivonen: "Pro-oxidant effects of normobaric hyperoxia in rat tissues." in: Acta physiologica Scandinavica, Vol. 145, Issue 2, pp. 151-7, 1992

Images

Product Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Application Details Handling References for anti-IL13 Receptor alpha 1 Antibody (ABIN108718) back to top
Supplier Images
 image for anti-IL13 Receptor alpha 1 antibody (Interleukin 13 Receptor, alpha 1) (Extracellular Domain) (ABIN108718) Specificity testing of GM1E7. BOSC cells were transiently transfected with an express...
 image for anti-IL13 Receptor alpha 1 antibody (Interleukin 13 Receptor, alpha 1) (Extracellular Domain) (ABIN108718) Specific inhibition of IL-13-dependentproliferation of TF-1 cells by GM-1E7. Sampleso...
ELISA image for anti-IL13 Receptor alpha 1 antibody (Interleukin 13 Receptor, alpha 1) (Extracellular Domain) (ABIN108718) Dose-dependent inhibition of cellular proliferation. Samples of TF-1 cells were incub...
SDS-PAGE (SDS) image for anti-IL13 Receptor alpha 1 antibody (Interleukin 13 Receptor, alpha 1) (Extracellular Domain) (ABIN108718) SDS-PAGE analysis of purified E7 monoclonal antibody. Lane 1: molecular weight marker...
Flow Cytometry (FACS) image for anti-IL13 Receptor alpha 1 antibody (Interleukin 13 Receptor, alpha 1) (Extracellular Domain) (ABIN108718) FACS analysis of BOSC23 cells using E6. BOSC23 cells were transiently transfected wit...
Flow Cytometry (FACS) image for anti-IL13 Receptor alpha 1 antibody (Interleukin 13 Receptor, alpha 1) (Extracellular Domain) (ABIN108718) FACS analysis of BOSC23 cells using E6. BOSC23 cells were transiently transfected wit...