anti-Human IL13 Receptor alpha 1 antibody for ELISA

Recommended IL13 Receptor alpha 1 Antibody (supplied by: Log in to see )

Antigen
Interleukin 13 Receptor, alpha 1 (IL13RA1) Antibodies
  • IL13RA1
  • il-13ra1
  • si:ch211-150g2.2
  • CD213A1
  • IL-13Ra
  • NR4
  • AI882074
  • CD213a1
  • IL-13r[a]
  • Il13ra
  • interleukin 13 receptor, alpha 1
  • IL13RA1
  • il13ra1
  • Il13ra1
Epitope
Extracellular Domain
30
14
11
8
7
6
6
5
5
5
4
4
4
4
3
2
2
2
2
1
1
1
1
Reactivity
Human
124
32
13
4
2
1
1
1
1
1
1
Host
Mouse
81
52
4
Clonality
Monoclonal
Conjugate
This IL13 Receptor alpha 1 antibody is un-conjugated
12
5
5
4
4
3
3
3
3
3
3
2
2
2
2
1
Application
Antagonist (Anta), Cell-ELISA (cELISA), Flow Cytometry (FACS), ELISA
84
52
44
26
16
11
8
6
6
4
4
2
2
2
2
2
1
1
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Catalog No. ABIN108718
$ 386.93
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.005616 ABIN393517 ELISA WB Mouse IgG1 kappa AA 1-428 Log in to see 1F5
11.005616 ABIN561475 ELISA WB Mouse IgG1 kappa AA 1-427, full length Log in to see 1F5
1 ABIN1531663 IF ELISA WB Rabbit IgG AA 371-420, pTyr405 Log in to see Polyclonal
1 ABIN1997815 ELISA Mouse IgG1 AA 1-343, Extracellular Domain Log in to see 6E6E1C3 1
1 ABIN3182446 ELISA IF WB Rabbit IgG pTyr405 Log in to see Polyclonal
1 ABIN3185158 ELISA IF IHC WB Rabbit IgG Ser561 Log in to see Polyclonal
1 ABIN2888882 IF IHC (p) ELISA WB Rabbit IgG AA 371-420 Log in to see Polyclonal
1 ABIN1997821 ELISA Rabbit IgG AA 1-343, Extracellular Domain Log in to see Polyclonal
1 ABIN2883919 ELISA IF WB Rabbit IgG pTyr405 Log in to see Polyclonal
1 ABIN2609458 ELISA WB Rabbit IgG AA 55-85 Log in to see Polyclonal
1 ABIN2290648 ELISA WB Rabbit IgG N-Term, AA 55-85 Log in to see Polyclonal
1 ABIN1828222 ELISA WB Mouse IgG1, kappa AA 1-427 Log in to see 1F5
1 ABIN1904928 ELISA WB PE Rabbit IgG AA 55-85 Log in to see Polyclonal
1 ABIN1904927 ELISA WB FITC Rabbit IgG AA 55-85 Log in to see Polyclonal
1 ABIN1904923 ELISA WB HRP Rabbit IgG AA 55-85 Log in to see Polyclonal
1 ABIN1904925 ELISA WB APC Rabbit IgG AA 55-85 Log in to see Polyclonal
1 ABIN1904924 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 55-85 Log in to see Polyclonal
1 ABIN1904926 ELISA WB Biotin Rabbit IgG AA 55-85 Log in to see Polyclonal
1 ABIN2623892 ELISA WB FITC Rabbit IgG AA 137-210 Log in to see Polyclonal
1 ABIN2623891 ELISA WB FITC Rabbit IgG AA 203-376 Log in to see Polyclonal

General

Antigen Interleukin 13 Receptor, alpha 1 (IL13RA1) Antibodies
Epitope Extracellular Domain
(30), (14), (11), (8), (7), (6), (6), (5), (5), (5), (4), (4), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human
(124), (32), (13), (4), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(81), (52), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL13 Receptor alpha 1 antibody is un-conjugated
(12), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1)
Application Antagonist (Anta), Cell-ELISA (cELISA), Flow Cytometry (FACS), ELISA
(84), (52), (44), (26), (16), (11), (8), (6), (6), (4), (4), (2), (2), (2), (2), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-IL13 Receptor alpha 1 Antibody

Target Details IL13 Receptor alpha 1 Application Details Handling References for anti-IL13 Receptor alpha 1 antibody (ABIN108718) Images
Specificity GM1E7 recognises IL-13Ralpha1 transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on monocytes (Myrtek et al., 2004).
Purification Protein G
Immunogen genetic immunisation with cDNA encoding human IL13-Ralpha1 (extracellular domain)
Clone GM-1E7
Isotype IgG1

Target Details IL13 Receptor alpha 1

Product Details anti-IL13 Receptor alpha 1 Antibody Application Details Handling References for anti-IL13 Receptor alpha 1 antibody (ABIN108718) Images back to top
Antigen
Alternative Name IL13Ra1 (IL13RA1 Antibody Abstract)
Background Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Rα1 together with IL-4Rα forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation.
UniProt P78552
Pathways JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Handling References for anti-IL13 Receptor alpha 1 antibody (ABIN108718) Images back to top
Application Notes Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.
Restrictions For Research Use only

Handling

Product Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Application Details References for anti-IL13 Receptor alpha 1 antibody (ABIN108718) Images back to top
Buffer PBS, pH 7.2
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C
Storage Comment short term: 2 °C - 8 °C, long term: -20 °C

References for anti-IL13 Receptor alpha 1 antibody (ABIN108718)

Product Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Application Details Handling Images back to top
Background publications

Natoli, Lüpertz, Merz, Müller, Köhler, Krammer, Li-Weber: "Targeting the IL-4/IL-13 signaling pathway sensitizes Hodgkin lymphoma cells to chemotherapeutic drugs." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 8, pp. 1945-54, 2013

Krause, Behrends, Borowski, Lohrmann, Lang, Myrtek, Lorenzen, Virchow, Luttmann, Friedrich: "Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor alpha1." in: Molecular immunology, Vol. 43, Issue 11, pp. 1799-807, 2006

Myrtek, Knoll, Matthiesen, Krause, Lohrmann, Schillinger, Idzko, Virchow, Friedrich, Luttmann: "Expression of interleukin-13 receptor alpha 1-subunit on peripheral blood eosinophils is regulated by cytokines." in: Immunology, Vol. 112, Issue 4, pp. 597-604, 2004

Ahotupa, Mäntylä, Peltola, Puntala, Toivonen: "Pro-oxidant effects of normobaric hyperoxia in rat tissues." in: Acta physiologica Scandinavica, Vol. 145, Issue 2, pp. 151-7, 1992

Images

Product Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Application Details Handling References for anti-IL13 Receptor alpha 1 antibody (ABIN108718) back to top
Supplier Images
 image for anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (Extracellular Domain) antibody (ABIN108718) Specificity testing of GM1E7. BOSC cells were transiently transfected with an express...
 image for anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (Extracellular Domain) antibody (ABIN108718) Specific inhibition of IL-13-dependentproliferation of TF-1 cells by GM-1E7. Sampleso...
ELISA image for anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (Extracellular Domain) antibody (ABIN108718) Dose-dependent inhibition of cellular proliferation. Samples of TF-1 cells were incub...
SDS-PAGE (SDS) image for anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (Extracellular Domain) antibody (ABIN108718) SDS-PAGE analysis of purified E7 monoclonal antibody. Lane 1: molecular weight marker...
Flow Cytometry (FACS) image for anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (Extracellular Domain) antibody (ABIN108718) FACS analysis of BOSC23 cells using E6. BOSC23 cells were transiently transfected wit...
Flow Cytometry (FACS) image for anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (Extracellular Domain) antibody (ABIN108718) FACS analysis of BOSC23 cells using E6. BOSC23 cells were transiently transfected wit...