anti-Mouse (Murine) IL15 antibody for Functional Studies

Recommended IL15 Antibody (supplied by: Log in to see )

Antigen
Interleukin 15 (IL15) Antibodies
  • IL15
  • AI503618
  • IL-15
  • interleukin 15
  • IL15
  • Il15
Reactivity
Mouse (Murine)
227
66
26
10
8
6
5
2
2
1
1
1
Host
Rat
147
123
17
16
5
5
Clonality
Monoclonal
Conjugate
This IL15 antibody is un-conjugated
36
17
11
9
7
5
5
5
5
5
4
3
3
3
3
3
3
3
2
2
2
2
1
1
Application
Functional Studies (Func)
206
182
66
34
31
29
25
16
13
11
9
7
5
4
3
3
2
2
1
1
1
1
1
1
1
1
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Catalog No. ABIN1449229
$ 346.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN181596 EIA Func WB Rabbit Log in to see Polyclonal

General

Antigen Interleukin 15 (IL15) Antibodies
Reactivity Mouse (Murine)
(227), (66), (26), (10), (8), (6), (5), (2), (2), (1), (1), (1)
Host Rat
(147), (123), (17), (16), (5), (5)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL15 antibody is un-conjugated
(36), (17), (11), (9), (7), (5), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Application Functional Studies (Func)
(206), (182), (66), (34), (31), (29), (25), (16), (13), (11), (9), (7), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-IL15 Antibody

Target Details IL15 Application Details Handling References for anti-IL15 antibody (ABIN1449229) Images
Specificity This antibody reacts with mouse IL-15 and has the neutralizing activity to its function.
Purification Protein G agarose
Immunogen Mouse recombinant IL-15
Clone AIO-3
Isotype IgG2a

Target Details IL15

Product Details anti-IL15 Antibody Application Details Handling References for anti-IL15 antibody (ABIN1449229) Images back to top
Antigen
Alternative Name Interleukin-15 / IL15 (IL15 Antibody Abstract)
Background Interleukin-15 (IL-15) is a multi-functional, 14 kDa glycoprotein produced by human fetal astrocytes and microglia in response to IL1-ß, IFN-γ, or TNF-a. High levels of IL15 mRNA are also found in muscle and placenta. IL-15 plays a role in T-cell mediated immune responses in the human central nervous system. IL-15 functions as a specific maturation factor and survival factor for NK-cells and it induces mast cell proliferation and the generation of cytolytic cells. IL-15 also inhibits apoptosis induced by Fas, dexamethasone, or cytokine deprivation activated T-cells. An alternative splicing variant of IL-15 has been observed in human small cell lung cancer cell lines.Synonyms: IL-15
Gene ID 3600
NCBI Accession NP_000576
UniProt P40933
Pathways JAK-STAT Signaling, Glycosaminoglycan Metabolic Process

Application Details

Product Details anti-IL15 Antibody Target Details IL15 Handling References for anti-IL15 antibody (ABIN1449229) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL15 Antibody Target Details IL15 Application Details References for anti-IL15 antibody (ABIN1449229) Images back to top
Concentration 1.0 mg/mL
Buffer PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Upon receipt, store (in aliqouts) at -20 °C.

References for anti-IL15 antibody (ABIN1449229)

Product Details anti-IL15 Antibody Target Details IL15 Application Details Handling Images back to top
Background publications

Shih, Kurman: "Molecular basis of gestational trophoblastic diseases." in: Current molecular medicine, Vol. 2, Issue 1, pp. 1-12, 2002

Ohteki, Suzue, Maki, Ota, Koyasu: "Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response." in: Nature immunology, Vol. 2, Issue 12, pp. 1138-43, 2001

Ohteki, Yoshida, Matsuyama, Duncan, Mak, Ohashi: "The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells." in: The Journal of experimental medicine, Vol. 187, Issue 6, pp. 967-72, 1998

Ohteki, Ho, Suzuki, Mak, Ohashi: "Role for IL-15/IL-15 receptor beta-chain in natural killer 1.1+ T cell receptor-alpha beta+ cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 12, pp. 5931-5, 1998

Images

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Supplier Images
 image for anti-Interleukin 15 (IL15) antibody (ABIN1449229) anti-Interleukin 15 (IL15) antibody