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anti-Mouse (Murine) IL15 antibody for Functional Studies

Recommended IL15 Antibody (supplied by: Log in to see )

Antigen
Interleukin 15 (IL15) Antibodies
  • AI503618
  • IL-15
  • IL15
Reactivity
Mouse (Murine)
194
44
22
7
6
6
3
1
1
Host
Rat
132
98
11
7
5
4
Clonality
Monoclonal
Conjugate
This IL15 antibody is un-conjugated
32
16
10
6
5
5
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func)
176
161
35
34
26
23
12
10
9
8
8
6
6
5
3
1
1
1
1
1
1
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Catalog No. ABIN1449229
$ 346.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008758347 ABIN282538 Func Neut Rat IgG2a lambda Log in to see AIO-3
0.0008758347 ABIN181596 EIA Func WB Rabbit Log in to see Polyclonal

Top referenced anti-IL15 antibody for Functional Studies

Similar anti-IL15 Antibodies

Application / Reactivity Mouse (Murine)
Blocking Antibody (Inhibition) 1 Antibodies
ELISA 23 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Functional Studies (Func) 3 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Neutralization (Neut) 10 Antibodies
Western Blotting (WB) 35 Antibodies

General

Antigen Interleukin 15 (IL15) Antibodies
Reactivity Mouse (Murine)
(194), (44), (22), (7), (6), (6), (3), (1), (1)
Host Rat
(132), (98), (11), (7), (5), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL15 antibody is un-conjugated
(32), (16), (10), (6), (5), (5), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func)
(176), (161), (35), (34), (26), (23), (12), (10), (9), (8), (8), (6), (6), (5), (3), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-IL15 Antibody

Target Details IL15 Application Details Handling References for anti-IL15 Antibody (ABIN1449229) Images
Specificity This antibody reacts with mouse IL-15 and has the neutralizing activity to its function.
Purification Protein G agarose
Immunogen Mouse recombinant IL-15
Clone AIO-3
Isotype IgG2a

Target Details IL15

Product Details anti-IL15 Antibody Application Details Handling References for anti-IL15 Antibody (ABIN1449229) Images back to top
Antigen
Alternative Name Interleukin-15 / IL15 (IL15 Antibody Abstract)
Background Interleukin-15 (IL-15) is a multi-functional, 14 kDa glycoprotein produced by human fetal astrocytes and microglia in response to IL1-ß, IFN-γ, or TNF-a. High levels of IL15 mRNA are also found in muscle and placenta. IL-15 plays a role in T-cell mediated immune responses in the human central nervous system. IL-15 functions as a specific maturation factor and survival factor for NK-cells and it induces mast cell proliferation and the generation of cytolytic cells. IL-15 also inhibits apoptosis induced by Fas, dexamethasone, or cytokine deprivation activated T-cells. An alternative splicing variant of IL-15 has been observed in human small cell lung cancer cell lines.Synonyms: IL-15
Gene ID 3600
NCBI Accession NP_000576
UniProt P40933
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL15 Antibody Target Details IL15 Handling References for anti-IL15 Antibody (ABIN1449229) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL15 Antibody Target Details IL15 Application Details References for anti-IL15 Antibody (ABIN1449229) Images back to top
Concentration 1.0 mg/mL
Buffer PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Upon receipt, store (in aliqouts) at -20 °C.

References for anti-IL15 Antibody (ABIN1449229)

Product Details anti-IL15 Antibody Target Details IL15 Application Details Handling Images back to top
Background publications

Shih, Kurman: "Molecular basis of gestational trophoblastic diseases." in: Current molecular medicine, Vol. 2, Issue 1, pp. 1-12, 2002

Ohteki, Suzue, Maki, Ota, Koyasu: "Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response." in: Nature immunology, Vol. 2, Issue 12, pp. 1138-43, 2001

Ohteki, Yoshida, Matsuyama, Duncan, Mak, Ohashi: "The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells." in: The Journal of experimental medicine, Vol. 187, Issue 6, pp. 967-72, 1998

Ohteki, Ho, Suzuki, Mak, Ohashi: "Role for IL-15/IL-15 receptor beta-chain in natural killer 1.1+ T cell receptor-alpha beta+ cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 12, pp. 5931-5, 1998

Images

Product Details anti-IL15 Antibody Target Details IL15 Application Details Handling References for anti-IL15 Antibody (ABIN1449229) back to top
Supplier Images
 image for anti-IL15 antibody (Interleukin 15) (ABIN1449229) anti-Interleukin 15 (IL15) antibody