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anti-Human IL15RA antibody for Immunohistochemistry

Recommended IL15RA Antibody (supplied by: Log in to see )

Antigen
Interleukin 15 Receptor, alpha (IL15RA) Antibodies
  • IL15RA
  • CD215
  • AA690181
  • IL-15RA
  • interleukin 15 receptor, alpha
  • interleukin 15 receptor, alpha chain
  • IL15RA
  • Il15ra
Epitope
AA 31-172
16
12
12
11
9
4
4
4
3
2
1
1
1
1
1
Reactivity
Human
122
55
29
1
1
1
1
1
1
1
Host
Goat
63
62
20
9
Clonality
Polyclonal
Conjugate
This IL15RA antibody is un-conjugated
9
7
6
6
6
5
5
5
5
5
5
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut), Western Blotting (WB)
92
79
40
13
6
4
3
3
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN4900622
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.145157 ABIN2431533 IHC ELISA Rabbit IgG Log in to see Polyclonal
1 ABIN2660994 CMCD Dep FACS IP IHC WB Biotin Mouse IgG2b kappa Log in to see JM7A4 9
1 ABIN1087607 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1087608 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2419467 IHC ELISA Rabbit IgG Log in to see Polyclonal
1 ABIN2144034 IHC ELISA WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-IL15RA antibody for Immunohistochemistry

Similar anti-IL15RA Antibodies

Application / Reactivity Human
Complement Mediated Cell Depletion (CMCD) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 1 Antibodies
Depletion (Dep) 1 Antibodies
ELISA 38 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 54 Antibodies
Gel Shift (GS) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Neutralization (Neut) 1 Antibodies
Western Blotting (WB) 83 Antibodies

General

Antigen Interleukin 15 Receptor, alpha (IL15RA) Antibodies
Epitope AA 31-172
(16), (12), (12), (11), (9), (4), (4), (4), (3), (2), (1), (1), (1), (1), (1)
Reactivity Human
(122), (55), (29), (1), (1), (1), (1), (1), (1), (1)
Host Goat
(63), (62), (20), (9)
Clonality
Polyclonal
Conjugate This IL15RA antibody is un-conjugated
(9), (7), (6), (6), (6), (5), (5), (5), (5), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut), Western Blotting (WB)
(92), (79), (40), (13), (6), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 13 references available
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Product Details anti-IL15RA Antibody

Target Details IL15RA Application Details Handling References for anti-IL15RA Antibody (ABIN4900622) Images
Specificity Detects human IL-15 R alpha in direct ELISAs and Western blots. In direct ELISAs, less than 10 % cross-reactivity with recombinant human IL-2 R gamma is observed.
Purification Antigen Affinity-purified
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant human, IL-15 R alpha , Ile31-Thr172, Accession # EAW86418
Isotype IgG

Target Details IL15RA

Product Details anti-IL15RA Antibody Application Details Handling References for anti-IL15RA Antibody (ABIN4900622) Images back to top
Antigen
Alternative Name IL-15 R alpha (IL15RA Antibody Abstract)
Background Alternative Names: CD215, CD215 antigen, IL-15 receptor subunit alpha, IL15R alpha, IL15RA, IL-15RA, IL-15R-alpha, interleukin 15 receptor, alpha, interleukin-15 receptor subunit alpha, MGC104179
Gene ID 3601
Research Area Signaling, Apoptosis/Necrosis
Pathways JAK-STAT Signaling, TCR Signaling

Application Details

Product Details anti-IL15RA Antibody Target Details IL15RA Handling References for anti-IL15RA Antibody (ABIN4900622) Images back to top
Application Notes Western Blot 0.1 μg/mL
Flow Cytometry 2.5 μg/10^6 cells
Immunohistochemistry 5-15 μg/mL
Neutralization 1-4 μg/mL
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL15RA Antibody Target Details IL15RA Application Details References for anti-IL15RA Antibody (ABIN4900622) Images back to top
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-IL15RA Antibody (ABIN4900622)

Product Details anti-IL15RA Antibody Target Details IL15RA Application Details Handling Images back to top
Product cited in:

Mattiola, Pesant, Tentorio, Molgora, Marcenaro, Lugli, Locati, Mavilio: "Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2818-28, 2015 Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

Bergamaschi, Kulkarni, Rosati, Alicea, Jalah, Chen, Bear, Sardesai, Valentin, Felber, Pavlakis: "Intramuscular delivery of heterodimeric IL-15 DNA in macaques produces systemic levels of bioactive cytokine inducing proliferation of NK and T cells." in: Gene therapy, Vol. 22, Issue 1, pp. 76-86, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Romero, Chaput, Poirier-Colame, Rusakiewicz, Jacquelot, Chaba, Mortier, Jacques, Caillat-Zucman, Flament, Caignard, Messaoudene, Aupérin, Vielh, Dessen, Porta, Mateus, Ayyoub, Valmori, Eggermont et al.: "Regulation of CD4(+)NKG2D(+) Th1 cells in patients with metastatic melanoma treated with sorafenib: role of IL-15Rα and NKG2D triggering. ..." in: Cancer research, Vol. 74, Issue 1, pp. 68-80, 2014 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Müller, Waldmann, Kruhlak, Dubois: "Paracrine and transpresentation functions of IL-15 are mediated by diverse splice versions of IL-15Rα in human monocytes and dendritic cells." in: The Journal of biological chemistry, Vol. 287, Issue 48, pp. 40328-38, 2012 Method employed by authors: ELISA (ELISA) (Sample species: Human).

Giron-Michel, Azzi, Khawam, Mortier, Caignard, Devocelle, Ferrini, Croce, François, Lecru, Charpentier, Chouaib, Azzarone, Eid: "Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway." in: PLoS ONE, Vol. 7, Issue 2, pp. e31624, 2012 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Giron-Michel, Menard, Negrini, Devocelle, Azzarone, Besson: "EBV-associated mononucleosis does not induce long-term global deficit in T-cell responsiveness to IL-15." in: Blood, Vol. 113, Issue 19, pp. 4541-7, 2009 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Eberly, Kader, Hassan, Rogers, Zhou, Mueller, Mattapallil, Piatak, Lifson, Katsikis, Roederer, Villinger, Mattapallil: "Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1439-48, 2009 Method employed by authors: Flow Cytometry (FACS) (Sample species: Rhesus Monkey).

Miranda-Carús, Benito-Miguel, Llamas, Balsa, Martín-Mola: "Human T cells constitutively express IL-15 that promotes ex vivo T cell homeostatic proliferation through autocrine/juxtacrine loops." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 6, pp. 3656-62, 2005 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Tejman-Yarden, Zlotnik, Lewis, Etzion, Chaimovitz, Douvdevani: "Renal cells express a functional interleukin-15 receptor." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 20, Issue 3, pp. 516-23, 2005 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Ferlazzo, Pack, Thomas, Paludan, Schmid, Strowig, Bougras, Muller, Moretta, Münz: "Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 47, pp. 16606-11, 2004 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Yamasaki, Maeda, Ohshima, Kikuchi, Otsuka, Harada: "Growth and apoptosis of human natural killer cell neoplasms: role of interleukin-2/15 signaling." in: Leukemia research, Vol. 28, Issue 10, pp. 1023-31, 2004 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Miranda-Carús, Balsa, Benito-Miguel, Pérez de Ayala, Martín-Mola: "IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 2, pp. 1463-76, 2004 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Hessian, Highton, Kean, Sun, Chin: "Cytokine profile of the rheumatoid nodule suggests that it is a Th1 granuloma." in: Arthritis and rheumatism, Vol. 48, Issue 2, pp. 334-8, 2003 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Images

Product Details anti-IL15RA Antibody Target Details IL15RA Application Details Handling References for anti-IL15RA Antibody (ABIN4900622) back to top
Supplier Images
Neutralization (Neut) image for anti-IL15RA antibody (Interleukin 15 Receptor, alpha) (AA 31-172) (ABIN4900622) IL-15 R alpha Inhibition of IL-15-dependent Cell Proliferation and Neutralization by ...
Immunohistochemistry (IHC) image for anti-IL15RA antibody (Interleukin 15 Receptor, alpha) (AA 31-172) (ABIN4900622) IL-15 R alpha in Human Prostate Cancer Tissue. IL-15 R alpha was detected in immersio...