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|Application / Reactivity||Mouse (Murine)|
|Flow Cytometry (FACS)||26 Antibodies|
|Functional Studies (Func)||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||13 Antibodies|
|Immunohistochemistry (IHC)||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||3 Antibodies|
|Neutralization (Neut)||3 Antibodies|
|Western Blotting (WB)||20 Antibodies|
|Antigen||Interleukin 15 Receptor, alpha (IL15RA) Antibodies|
|Epitope||AA 33-205 Alternatives|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This IL15RA antibody is un-conjugated Alternatives|
Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
|7 references available|
|Supplier||Log in to see|
Product Details anti-IL15RA AntibodyTarget Details IL15RA Application Details Handling References for anti-IL15RA Antibody (ABIN4900232) Images
|Specificity||Detects mouse IL-15 R alpha in direct ELISAs and Western blots. In direct ELISAs, approximately 5 % cross-reactivity with recombinant human (rh) IL-15 R alpha is observed and less than 1 % cross-reactivity with rhIL-2 R alpha , recombinant mouse (rm) IL-2 R beta , and rmIL-2 R gamma is observed.|
|Purification||Immunogen affinity purified|
|Sterility||0.2 μm filtered|
|Endotoxin Level||<0.10 EU per 1 μg of the antibody by the LAL method.|
|Immunogen||Mouse myeloma cell line NS0-derived recombinant mouse IL-15 R alpha , Gly33-Lys205, Accession # Q60819|
Target Details IL15RAProduct Details anti-IL15RA Antibody Application Details Handling References for anti-IL15RA Antibody (ABIN4900232) Images back to top
|Alternative Name||IL-15 R alpha (IL15RA Antibody Abstract)|
|Background||Alternative Names: CD215, CD215 antigen, IL-15 receptor subunit alpha, IL15R alpha, IL15RA, IL-15RA, IL-15R-alpha, interleukin 15 receptor, alpha, interleukin-15 receptor subunit alpha, MGC104179|
|Research Area||Signaling, Apoptosis/Necrosis|
|Pathways||JAK-STAT Signaling, TCR Signaling|
Application DetailsProduct Details anti-IL15RA Antibody Target Details IL15RA Handling References for anti-IL15RA Antibody (ABIN4900232) Images back to top
Western Blot 0.1 μg/mL
Flow Cytometry 2.5 μg/10^6 cells
Neutralization 0.3-1.5 μg/mL
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL15RA Antibody Target Details IL15RA Application Details References for anti-IL15RA Antibody (ABIN4900232) Images back to top
|Reconstitution||Reconstitute at 0.2 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-IL15RA Antibody (ABIN4900232)Product Details anti-IL15RA Antibody Target Details IL15RA Application Details Handling Images back to top
|Product cited in:||
Freeman, Meyer, Slifka: "Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions." in: Journal of virology, Vol. 88, Issue 13, pp. 7474-84, 2014 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).
Klezovich-Bénard, Corre, Jusforgues-Saklani, Fiole, Burjek, Tournier, Goossens: "Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins." in: PLoS pathogens, Vol. 8, Issue 1, pp. e1002481, 2012 Method employed by authors: Neutralization (Neut) (Sample species: Mouse (Murine)).
Müller, Waldmann, Kruhlak, Dubois: "Paracrine and transpresentation functions of IL-15 are mediated by diverse splice versions of IL-15Rα in human monocytes and dendritic cells." in: The Journal of biological chemistry, Vol. 287, Issue 48, pp. 40328-38, 2012 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).
McCullar, Oostendorp, Panoskaltsis-Mortari, Yun, Lutz, Wagner, Miller: "Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15." in: Experimental hematology, Vol. 36, Issue 5, pp. 598-608, 2008 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).
Yang, Tian, Ling, Trendell-Smith, Ma, Lo, Stott, Liew, Huang: "Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: roles of IL-2 versus IL-15." in: European journal of immunology, Vol. 38, Issue 6, pp. 1664-76, 2008 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).
Chaudhry, Kingham, Plitas, Katz, Raab, DeMatteo: "Combined stimulation with interleukin-18 and CpG induces murine natural killer dendritic cells to produce IFN-gamma and inhibit tumor growth." in: Cancer research, Vol. 66, Issue 21, pp. 10497-504, 2006 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).
Gould, Greene, Bhoj, DeVecchio, Heinzel: "Distinct modulatory effects of LPS and CpG on IL-18-dependent IFN-gamma synthesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 3, pp. 1754-62, 2004 Method employed by authors: Neutralization (Neut) (Sample species: Mouse (Murine)).
ImagesProduct Details anti-IL15RA Antibody Target Details IL15RA Application Details Handling References for anti-IL15RA Antibody (ABIN4900232) back to top