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|Antigen||Interleukin 2 (IL2) Antibodies|
|Epitope||AA 21-155 Alternatives|
|Reactivity||Rat (Rattus) Alternatives|
|Conjugate||This IL2 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|4 references available|
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Product Details anti-IL2 AntibodyTarget Details IL2 Application Details Handling References for anti-IL2 antibody (ABIN3042519) Images
|Purpose||Rabbit IgG polyclonal antibody for Interleukin-2(IL-2) detection. Tested with WB in Rat.|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Interleukin-2(IL-2) detection. Tested with WB in Rat.
Gene Name: interleukin 2
Protein Name: Interleukin-2
|Purification||Immunogen affinity purified.|
|Immunogen||E.coli-derived rat IL-2 recombinant protein (Position: A21-Q155). Rat IL-2 shares 66% and 80% amino acid (aa) sequence identity with human and mouse IL-2, respectively.|
Target Details IL2Product Details anti-IL2 Antibody Application Details Handling References for anti-IL2 antibody (ABIN3042519) Images back to top
|Alternative Name||IL2 (IL2 Antibody Abstract)|
Interleukin-2 (IL2), formerly referred to as T-cell growth factor, is a powerfully immunoregulatory lymphokine that is produced by lectin- or antigen-activated T cells. It is produced not only by mature T lymphocytes on stimulation but also constitutively by certain T-cell lymphoma cell lines. The lymphokine interleukin-2 (IL-2) is responsible for autocrine cell cycle progression and regulation of immune responses. IL-2 expression in mature thymocytes and T cells has been found to be tightly controlled by monoallelic expression. IL-2 can act as a growth hormone for both B and T lymphocytes. This gene for interleukin 2 (IL2) is assigned to chromosome 4. IL-2 is a 15.5KDa glycoprotein, consisting of 153 amino acids in precursor form and 133 amino acids in mature form.
Synonyms: Aldesleukin antibody|IL 2 antibody|IL-2 antibody|IL2 antibody|IL2_HUMAN antibody|Interleukin 2 antibody|Interleukin-2 antibody|Interleukin2 antibody|Involved in regulation of T cell clonal expansion antibody|Lymphokine antibody|OTTHUMP00000164090 antibody|POIL2 antibody|T-cell growth factor antibody|TCGF antibody
|Research Area||Immunology, Innate Immunity, Cytokines|
|Pathways||JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation|
Application DetailsProduct Details anti-IL2 Antibody Target Details IL2 Handling References for anti-IL2 antibody (ABIN3042519) Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL2 Antibody Target Details IL2 Application Details References for anti-IL2 antibody (ABIN3042519) Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
References for anti-IL2 antibody (ABIN3042519)Product Details anti-IL2 Antibody Target Details IL2 Application Details Handling Images back to top
|Product cited in:||
Hu, Jing, Wang, Zhang, Yong, Wang: "The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D-Galactose-induced aged rat model." in: BMC complementary and alternative medicine, Vol. 15, pp. 119, 2015
Chen, Liu, Xu, Yang, Zhang, Zhang: "Effectiveness of immune therapy combined with chemotherapy on the immune function and recurrence rate of cervical cancer." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 1063-1067, 2015
Xie, Cao, Zhao, Yu, Qi, Dai: "IDO expressing dendritic cells suppress allograft rejection of small bowel transplantation in mice by expansion of Foxp3+ regulatory T cells." in: Transplant immunology, Vol. 33, Issue 2, pp. 69-77, 2015
Zhong, Shen, Sun, Wang, Zhang, Sun: "Additive effects of ulinastatin and docetaxel on growth of breast cancer xenograft in nude mice and expression of PGE2, IL-10, and IL-2 in primary breast cancer cells." in: Cancer biotherapy & radiopharmaceuticals, Vol. 27, Issue 4, pp. 252-8, 2012
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