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anti-Chemical IL2 Receptor beta antibody for Flow Cytometry

Recommended IL2 Receptor beta Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 Receptor, beta (IL2RB) Antibodies
  • CD122
  • Il-2/15Rbeta
  • il-2rb
  • Il-2Rbeta
  • IL-15Rbeta
  • IL2RB
  • IL2RBC
  • IL15RB
  • IL15Rbeta
  • p70
  • P70-75
Reactivity
Chemical, Mouse (Murine)
186
135
77
28
6
1
Host
Rat
118
110
62
Clonality
Monoclonal
Conjugate
This IL2 Receptor beta antibody is conjugated to PE-Cy7
36
31
22
11
4
4
4
3
3
2
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS)
174
90
51
46
27
22
12
11
9
6
3
2
2
2
2
1
1
Supplier
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Catalog No. ABIN2659079
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.3068567 ABIN2660928 BR FACS IHC Biotin Rat IgG2a kappa Log in to see 5H4 4
0.3068567 ABIN2660930 FACS Biotin Rat IgG2b kappa Log in to see TM-beta1 6
0.3068567 ABIN2656897 FACS APC Rat IgG2b kappa Log in to see TM-beta1 5
0.3068567 ABIN2661493 FACS FITC Rat IgG2b kappa Log in to see TM-beta1 5
0.3068567 ABIN2662986 FACS PE Rat IgG2a kappa Log in to see 5H4 4
0.3068567 ABIN2662988 FACS CyTOF PE Rat IgG2b kappa Log in to see TM-beta1 6
0.3068567 ABIN2658883 FACS APC Mouse IgG1 kappa Log in to see TU27 4
0.3068567 ABIN2659077 FACS PE-Cy7 Mouse IgG1 kappa Log in to see TU27 3
0.3068567 ABIN2665533 FACS Rat IgG2b kappa Log in to see TM-beta1 5
0.3068567 ABIN2665531 FACS IHC Mouse IgG1 kappa Log in to see TU27 3
0.3068567 ABIN2659942 FACS PerCP-Cy5.5 Mouse IgG1 kappa Log in to see TU27 3
0.3068567 ABIN2659944 FACS PerCP-Cy5.5 Rat IgG2b kappa Log in to see TM-beta1 5
0.3068567 ABIN2662984 ICC FACS IF ICFC IP IHC WB PE Mouse IgG1 kappa Log in to see TU27 3
0.3068567 ABIN2664178 FACS Mouse IgG1 kappa Log in to see TU27 3
0.3068567 ABIN2664179 FACS Rat IgG2a kappa Log in to see 5H4 5
0.0010666476 ABIN2659080 FACS PE-Cy7 Rat IgG2b kappa Log in to see TM-beta1 5
0.0010666476 ABIN2660927 BR FACS IHC Biotin Rat IgG2a kappa Log in to see 5H4 4
0.0010666476 ABIN2660929 FACS Biotin Rat IgG2b kappa Log in to see TM-beta1 6
0.0010666476 ABIN2656898 FACS APC Rat IgG2b kappa Log in to see TM-beta1 5
0.0010666476 ABIN2661492 FACS FITC Rat IgG2b kappa Log in to see TM-beta1 5

Top referenced anti-IL2 Receptor beta antibody for Flow Cytometry

Similar anti-IL2 Receptor beta Antibodies

Application / Reactivity Mouse (Murine) Chemical
Western Blotting (WB) 47 Antibodies 2 Antibodies
Neutralization (Neut) 1 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies 2 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Immunoprecipitation (IP) 50 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies
Immunohistochemistry (IHC) 17 Antibodies 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunofluorescence (IF) 8 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 3 Antibodies 2 Antibodies
Functional Studies (Func) 6 Antibodies
Flow Cytometry (FACS) 123 Antibodies

General

Antigen Interleukin 2 Receptor, beta (IL2RB) Antibodies
Reactivity Chemical, Mouse (Murine)
(186), (135), (77), (28), (6), (1)
Host Rat
(118), (110), (62)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2 Receptor beta antibody is conjugated to PE-Cy7
(36), (31), (22), (11), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS)
(174), (90), (51), (46), (27), (22), (12), (11), (9), (6), (3), (2), (2), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-IL2 Receptor beta Antibody

Target Details IL2 Receptor beta Application Details Handling References for anti-IL2 Receptor beta Antibody (ABIN2659079) Images
Purification The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
Clone TM-beta1
Isotype IgG2b kappa

Target Details IL2 Receptor beta

Product Details anti-IL2 Receptor beta Antibody Application Details Handling References for anti-IL2 Receptor beta Antibody (ABIN2659079) Images back to top
Antigen
Alternative Name CD122 (IL2RB Antibody Abstract)
Target Type Chemical
Background CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit(CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-β1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Handling References for anti-IL2 Receptor beta Antibody (ABIN2659079) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details References for anti-IL2 Receptor beta Antibody (ABIN2659079) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL2 Receptor beta Antibody (ABIN2659079)

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling Images back to top
Background publications

Suzuki, Kündig, Furlonger, Wakeham, Timms, Matsuyama, Schmits, Simard, Ohashi, Griesser: "Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta." in: Science (New York, N.Y.), Vol. 268, Issue 5216, pp. 1472-6, 1995

Minami, Kono, Miyazaki, Taniguchi: "The IL-2 receptor complex: its structure, function, and target genes." in: Annual review of immunology, Vol. 11, pp. 245-68, 1993

Tanaka, Kitamura, Nagasaka, Kuida, Suwa, Miyasaka: "Selective long-term elimination of natural killer cells in vivo by an anti-interleukin 2 receptor beta chain monoclonal antibody in mice." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 1103-7, 1993

Tanaka, Takeuchi, Shiohara, Kitamura, Nagasaka, Hamamura, Yagita, Miyasaka: "In utero treatment with monoclonal antibody to IL-2 receptor beta-chain completely abrogates development of Thy-1+ dendritic epidermal cells." in: International immunology, Vol. 4, Issue 4, pp. 487-91, 1992

Tanaka, Tsudo, Karasuyama, Kitamura, Kono, Hatakeyama, Taniguchi, Miyasaka: "A novel monoclonal antibody against murine IL-2 receptor beta-chain. Characterization of receptor expression in normal lymphoid cells and EL-4 cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 7, pp. 2222-8, 1991

Images

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling References for anti-IL2 Receptor beta Antibody (ABIN2659079) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-IL2 Receptor beta antibody (Interleukin 2 Receptor, beta)  (PE-Cy7) (ABIN2659079) anti-Interleukin 2 Receptor, beta (IL2RB) antibody (PE-Cy7)