You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) IL2 Receptor beta antibody for Flow Cytometry

Recommended IL2 Receptor beta Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 Receptor, beta (IL2RB) Antibodies
  • CD122
  • Il-2/15Rbeta
  • il-2rb
  • Il-2Rbeta
  • IL-15Rbeta
  • IL2RB
  • IL2RBC
  • IL15RB
  • IL15Rbeta
  • p70
  • P70-75
Reactivity
Mouse (Murine)
214
144
90
29
6
1
Host
Rat
146
112
82
Clonality
Monoclonal
Conjugate
This IL2 Receptor beta antibody is conjugated to FITC
36
32
24
11
8
7
5
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS)
222
91
54
46
28
22
13
11
9
6
5
3
3
2
2
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN371155
$ 368.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.301722 ABIN2659079 FACS PE-Cy7 Rat IgG2b kappa Log in to see TM-beta1 5
0.301722 ABIN2660928 BR FACS IHC Biotin Rat IgG2a kappa Log in to see 5H4 4
0.301722 ABIN2660930 FACS Biotin Rat IgG2b kappa Log in to see TM-beta1 6
0.301722 ABIN2656897 FACS APC Rat IgG2b kappa Log in to see TM-beta1 5
0.301722 ABIN2661493 FACS FITC Rat IgG2b kappa Log in to see TM-beta1 5
0.301722 ABIN2662986 FACS PE Rat IgG2a kappa Log in to see 5H4 4
0.301722 ABIN2662988 FACS CyTOF PE Rat IgG2b kappa Log in to see TM-beta1 6
0.301722 ABIN440135 FACS IP FITC Rat IgG2a kappa Log in to see 5H4
0.301722 ABIN440136 FACS IP Biotin Rat IgG2a kappa Log in to see 5H4
0.301722 ABIN2665533 FACS Rat IgG2b kappa Log in to see TM-beta1 5
0.301722 ABIN2659944 FACS PerCP-Cy5.5 Rat IgG2b kappa Log in to see TM-beta1 5
0.301722 ABIN2664179 FACS Rat IgG2a kappa Log in to see 5H4 5
0.301722 ABIN2677426 FACS PerCP-eFluor® 710 Rat IgG2b Log in to see TM-b1 (TM-beta1) 1
0.301722 ABIN2677424 FACS PE-Cy7 Rat IgG2b kappa Log in to see TM-b1 (TM-beta1)
0.301722 ABIN2677422 FACS APC Rat IgG2b kappa Log in to see TM-b1 (TM-beta1)
0.301722 ABIN2677428 FACS EFluor 450 Rat IgG2b Log in to see TM-b1 (TM-beta1)
0.301722 ABIN2168591 FACS FITC Rat IgG2a Log in to see 5H4
0.301722 ABIN2168589 FACS APC Rat IgG2a Log in to see 5H4
0.301722 ABIN2168590 FACS Biotin Rat IgG2a Log in to see 5H4
0.301722 ABIN2168593 FACS PE Rat IgG2a Log in to see 5H4

Top referenced anti-IL2 Receptor beta antibody for Flow Cytometry

Similar anti-IL2 Receptor beta Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 3 Antibodies
ELISA 28 Antibodies
Flow Cytometry (FACS) 151 Antibodies
Functional Studies (Func) 6 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 17 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies
Immunoprecipitation (IP) 53 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies
Neutralization (Neut) 4 Antibodies
Western Blotting (WB) 47 Antibodies

General

Antigen Interleukin 2 Receptor, beta (IL2RB) Antibodies
Reactivity Mouse (Murine)
(214), (144), (90), (29), (6), (1)
Host Rat
(146), (112), (82)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2 Receptor beta antibody is conjugated to FITC
(36), (32), (24), (11), (8), (7), (5), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Flow Cytometry (FACS)
(222), (91), (54), (46), (28), (22), (13), (11), (9), (6), (5), (3), (3), (2), (2), (2), (1), (1)
Pubmed 4 references available
Supplier Log in to see

Product Details anti-IL2 Receptor beta Antibody

Target Details IL2 Receptor beta Application Details Handling References for anti-IL2 Receptor beta Antibody (ABIN371155) Images
Specificity This antibody recognises beta chain (Mr. 90-100 kDa) of the IL-2 Receptor. It does not block IL-2 binding. (Ref.1)
Characteristics Synonyms: Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL2 Receptor beta, P70-75
Immunogen Rat myeloma YB2/0 transfected with truncated mouse IL-2RB cDNA. (Ref. 1)
Clone 5H4
Isotype IgG2a

Target Details IL2 Receptor beta

Product Details anti-IL2 Receptor beta Antibody Application Details Handling References for anti-IL2 Receptor beta Antibody (ABIN371155) Images back to top
Antigen
Alternative Name CD122 / IL2RB (IL2RB Antibody Abstract)
Background The IL-2 receptor is a complex of three distinct polypeptide chains: (i) the alpha chain which binds IL-2 with low affinity, (ii) the beta chain that binds IL-2 with high affinity, and (ii) the common gamma chain (gc) that does not bind IL-2. (Ref.2) The high affinity receptor complex is an alpha/beta/gamma heterotrimer with a Kd of 1.3 x 10e-11 M. (Ref.2) In mouse spleen, CD122 is expresed on ~30 % of CD8+ cells and all NK cells, but < 1 % of B cells and CD4+ T lymphocytes. In the thymus, its expression is confined to CD4-CD8+ single positive and CD4-CD8- double negative cells. (Ref.4) Cytoplasmic regions of the IL-2R beta chain are involved in IL-2-mediated cellular signaling and, via the interaction of IL-2 and its receptor complex, may be involved in the generation and differentiation of T lymphocytes. (Ref.1,4)Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75
Gene ID 16185
UniProt P16297
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Handling References for anti-IL2 Receptor beta Antibody (ABIN371155) Images back to top
Application Notes Flow Cytometry: < / = 1 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details References for anti-IL2 Receptor beta Antibody (ABIN371155) Images back to top
Concentration 0.5 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

References for anti-IL2 Receptor beta Antibody (ABIN371155)

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling Images back to top
Background publications

Malek, Furse, Fleming, Fadell, He: "Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 15, Issue 5, pp. 447-54, 1995

Minami, Kono, Miyazaki, Taniguchi: "The IL-2 receptor complex: its structure, function, and target genes." in: Annual review of immunology, Vol. 11, pp. 245-68, 1993

Taniguchi, Minami: "The IL-2/IL-2 receptor system: a current overview." in: Cell, Vol. 73, Issue 1, pp. 5-8, 1993

Tanaka, Tsudo, Karasuyama, Kitamura, Kono, Hatakeyama, Taniguchi, Miyasaka: "A novel monoclonal antibody against murine IL-2 receptor beta-chain. Characterization of receptor expression in normal lymphoid cells and EL-4 cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 7, pp. 2222-8, 1991

Images

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling References for anti-IL2 Receptor beta Antibody (ABIN371155) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-IL2 Receptor beta antibody (Interleukin 2 Receptor, beta)  (FITC) (ABIN371155) anti-Interleukin 2 Receptor, beta (IL2RB) antibody (FITC)