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Anti-CD25 (show IL2RA ELISA Kits) recombinant immunotoxin LMB-2 had phase I activity limited by immunogenicity and rapid growth.
Enhanced pretreatment CD25 (show IL2RA ELISA Kits) expression on CD4 (show CD4 ELISA Kits)+ T cells was associated with decreased survival rate of acute myeloid leukemia (show BCL11A ELISA Kits) patients.
A decrease of CD4 (show CD4 ELISA Kits)(+) CD25 (show IL2RA ELISA Kits)(+) CD127 (show IL7R ELISA Kits)(low) FoxP3 (show FOXP3 ELISA Kits)(+) regulatory T cells with impaired suppressive function had been found in untreated ulcerative colitis patients.
Serum IL1RA (show IL1RN ELISA Kits) and IL2RA (show IL2RA ELISA Kits) are predictors of event free survival in T-cell lymphoma.
Data show that an ultra-high level of serum serum soluble interleukin-2 (show IL2 ELISA Kits) receptor (sIL (show PMEL ELISA Kits)-2R) at diagnosis is a significant poor prognostic biomarker for angioimmunoblastic T-cell lymphoma (AITL).
The rs2104286 G allele in IL2RA is present at higher frequencies in neuromyelitis optica patients than in healthy controls within a Southern Han Chinese population.
Our results suggest that the CD34 (show CD34 ELISA Kits)/CD25 (show IL2RA ELISA Kits)/CD123 (show IL3RA ELISA Kits)/CD99 (show CD99 ELISA Kits)(+) LAIP is strictly associated with FLT3 (show FLT3 ELISA Kits)-ITD-positive cells.
Interleukin-2 Receptor alpha-Chain (CD25 (show IL2RA ELISA Kits)) Expression Predicts a Poor Prognosis in Acute Myeloid Leukemia (show BCL11A ELISA Kits)
Data show that interleukin 2 receptor subunit alpha (IL2RA (show IL2RA ELISA Kits))-single nucleotide polymorphism rs2104286 and serum sIL2Ralpha-level associated with rheumatoid arthritis (RA)-persistence.
CD4 (show CD4 ELISA Kits)+CD45RO+CD25 (show IL2RA ELISA Kits)-/lowCD127+: CD4 (show CD4 ELISA Kits)+CD45RO+CD25hiCD127-/low ratio in peripheral blood indicates heart transplant recipients at risk for cardiac allograft vasculopathy.
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
IL-2 receptor subunit alpha
, IL-2R subunit alpha
, TAC antigen
, interleukin-2 receptor subunit alpha