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A decrease of CD4 (show CD4 Proteins)(+) CD25 (show IL2RA Proteins)(+) CD127 (show IL7R Proteins)(low) FoxP3 (show FOXP3 Proteins)(+) regulatory T cells with impaired suppressive function had been found in untreated ulcerative colitis patients.
Serum IL1RA (show IL1RN Proteins) and IL2RA (show IL2RA Proteins) are predictors of event free survival in T-cell lymphoma.
Data show that an ultra-high level of serum serum soluble interleukin-2 receptor (sIL-2R) at diagnosis is a significant poor prognostic biomarker for angioimmunoblastic T-cell lymphoma (AITL).
The rs2104286 G allele in IL2RA is present at higher frequencies in neuromyelitis optica patients than in healthy controls within a Southern Han Chinese population.
Our results suggest that the CD34 (show CD34 Proteins)/CD25 (show IL2RA Proteins)/CD123 (show IL3RA Proteins)/CD99 (show CD99 Proteins)(+) LAIP is strictly associated with FLT3 (show FLT3 Proteins)-ITD-positive cells.
Interleukin-2 Receptor alpha-Chain (CD25 (show IL2RA Proteins)) Expression Predicts a Poor Prognosis in Acute Myeloid Leukemia (show BCL11A Proteins)
Data show that interleukin 2 receptor subunit alpha (IL2RA (show IL2RA Proteins))-single nucleotide polymorphism rs2104286 and serum sIL2Ralpha-level associated with rheumatoid arthritis (RA)-persistence.
CD4 (show CD4 Proteins)+CD45RO+CD25 (show IL2RA Proteins)-/lowCD127+: CD4 (show CD4 Proteins)+CD45RO+CD25hiCD127-/low ratio in peripheral blood indicates heart transplant recipients at risk for cardiac allograft vasculopathy.
analysis of sIL-2R levels in sarcoidosis patients with renal insufficiency
all five single nucleotide polymorphisms in the IL2RA (show IL2RA Proteins) gene are risk factors for type 1 diabetes risk.
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
IL-2 receptor subunit alpha
, IL-2R subunit alpha
, TAC antigen
, interleukin-2 receptor subunit alpha