anti-Human IL2RG antibody for Flow Cytometry

Recommended IL2RG Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 Receptor, gamma (IL2RG) Antibodies
  • Ab2-183
  • Cd132
  • CD132
  • CIDX
  • IL-2RG
  • IMD4
  • P64
  • SCIDX
  • SCIDX1
  • [g]c
  • gamma(c)
  • gc
  • interleukin 2 receptor, gamma
  • interleukin 2 receptor, gamma chain
  • IL2RG
  • il2rg
  • Il2rg
Epitope
AA 23-254
15
15
12
10
8
8
8
7
7
5
5
4
4
4
3
3
2
2
1
1
Reactivity
Human
122
79
29
2
1
Host
Mouse
89
42
31
2
Clonality
Monoclonal
Conjugate
This IL2RG antibody is un-conjugated
11
10
9
5
5
5
5
5
5
4
4
4
3
3
2
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut)
76
70
46
15
13
6
4
3
3
3
3
2
1
1
1
1
1
Supplier
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Catalog No. ABIN4899740
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.327464 ABIN951187 FACS WB Rabbit Ig N-Term, AA 82-111 Log in to see Polyclonal 3
14.327464 ABIN4896578 FACS PE Mouse IgG2a AA 23-254 Log in to see 31134 2
14.327464 ABIN4896581 FACS PE Mouse IgG2b AA 23-254 Log in to see 633162 1
14.327464 ABIN653403 FACS WB Rabbit Ig AA 76-101, N-Term Log in to see Polyclonal
14.327464 ABIN2658473 FACS APC Rat IgG2b kappa Log in to see TUGh4 8
14.327464 ABIN2663004 FACS PE Rat IgG2b kappa Log in to see TUGh4 6
14.327464 ABIN4896576 FACS Allophycocyanin Mouse IgG2a AA 23-254 Log in to see 31134
14.327464 ABIN4896577 FACS Fluorescein Mouse IgG2a AA 23-254 Log in to see 31134
14.327464 ABIN4896579 FACS Allophycocyanin Mouse IgG2b AA 23-254 Log in to see 633162
14.327464 ABIN4896580 FACS Fluorescein Mouse IgG2b AA 23-254 Log in to see 633162
1 ABIN4899741 CyTOF FACS Neut WB Goat IgG AA 23-254 Log in to see Polyclonal 3
1 ABIN4899739 CyTOF FACS Mouse IgG2a AA 23-254 Log in to see 31134 2
1 ABIN4899738 FACS WB Biotin Goat IgG AA 23-254 Log in to see Polyclonal 2
1 ABIN474409 FACS Biotin Rat IgG2b, lambda Log in to see TUGh4
1 ABIN2688955 FACS Biotin Rat IgG2b, kappa Log in to see TUGh4 2
1 ABIN2688953 FACS Rat IgG2b, kappa Log in to see TUGh4 1
1 ABIN2658474 FACS APC Rat IgG2b kappa Log in to see TUGh4 8
1 ABIN2663005 FACS PE Rat IgG2b kappa Log in to see TUGh4 6
1 ABIN2665537 FACS IF IHC Rat IgG2b kappa Log in to see TUGh4 6
1 ABIN2664201 FACS Rat IgG2b kappa Log in to see TUGh4 6

General

Antigen Interleukin 2 Receptor, gamma (IL2RG) Antibodies
Epitope AA 23-254
(15), (15), (12), (10), (8), (8), (8), (7), (7), (5), (5), (4), (4), (4), (3), (3), (2), (2), (1), (1)
Reactivity Human
(122), (79), (29), (2), (1)
Host Mouse
(89), (42), (31), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2RG antibody is un-conjugated
(11), (10), (9), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Application Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut)
(76), (70), (46), (15), (13), (6), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-IL2RG Antibody

Target Details IL2RG Application Details Handling ProductDetails: References for anti-IL2RG antibody (ABIN4899740) Images
Specificity Detects human Common gamma Chain/IL-2 R gamma in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha , rhIL-2 R beta , rhIL-15 R alpha , recombinant mouse IL-2 R gamma , or recombinant canine IL-2 R alpha is observed. In Western blots, approximately 80 % cross-reactivity with recombinant human IL-2 R beta , 50 % cross-reactivity with rhIL-15 R alpha and recombinant mouse IL-2 R alpha , and no cross-reactivity with rhIL-2 R alpha is observed.
Purification Protein A or G purified from hybridoma culture supernatant
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen S. frugiperda insect ovarian cell line Sf21-derived recombinant human Common gamma Chain/IL-2 gamma , Leu23-Asn254, Accession # P31785
Clone 633162
Isotype IgG2b

Target Details IL2RG

Product Details anti-IL2RG Antibody Application Details Handling ProductDetails: References for anti-IL2RG antibody (ABIN4899740) Images back to top
Antigen
Alternative Name IL2RG (IL2RG Antibody Abstract)
Background Alternative Names: CD132, CD132 antigen, CIDX, combined immunodeficiency, X-linked, common cytokine receptor gamma chain, common gamma-chain, cytokine receptor common subunit gamma, gamma(c), IL-2 R gamma, IL-2 receptor subunit gamma, IL2R gamma, IL-2R subunit gamma, IL2RG, IL-2RG, IMD4, interleukin 2 receptor, gamma, Interleukin-2 receptor subunit gamma, p64, SCIDX, SCIDX1, severe combined immunodeficiency
Gene ID 3561
UniProt P31785
Pathways JAK-STAT Signaling, Growth Factor Binding

Application Details

Product Details anti-IL2RG Antibody Target Details IL2RG Handling ProductDetails: References for anti-IL2RG antibody (ABIN4899740) Images back to top
Application Notes Flow Cytometry 2.5 μg/10^6 cells
Neutralization 0.08-0.4 μg/mL
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL2RG Antibody Target Details IL2RG Application Details ProductDetails: References for anti-IL2RG antibody (ABIN4899740) Images back to top
Reconstitution Sterile PBS to a final concentration of 0.5 mg/mL.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

ProductDetails: References for anti-IL2RG antibody (ABIN4899740)

Product Details anti-IL2RG Antibody Target Details IL2RG Application Details Handling Images back to top
Product cited in:

Jiang, Chen, An, Yang, Zhang, Cheng: "Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling." in: Scientific reports, Vol. 6, pp. 32320, 2016 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Mujib, Jones, Lo, Aidarus, Clayton, Sakhdari, Benko, Kovacs, Ostrowski et al.: "Antigen-independent induction of Tim-3 expression on human T cells by the common ?-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 8, pp. 3745-56, 2012 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Giron-Michel, Azzi, Khawam, Mortier, Caignard, Devocelle, Ferrini, Croce, François, Lecru, Charpentier, Chouaib, Azzarone, Eid: "Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway." in: PLoS ONE, Vol. 7, Issue 2, pp. e31624, 2012 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Images

Product Details anti-IL2RG Antibody Target Details IL2RG Application Details Handling ProductDetails: References for anti-IL2RG antibody (ABIN4899740) back to top
Supplier Images
Neutralization (Neut) image for anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-254) antibody (ABIN4899740) Cell Proliferation Induced by IL-2 and Neutralization by Human Common gamma Chain/ IL...
Flow Cytometry (FACS) image for anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-254) antibody (ABIN4899740) Detection of Common gamma Chain/IL-2 R gamma in Human PBMC by Flow Cytometry. Human p...
Neutralization (Neut) image for anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-254) antibody (ABIN4899740) Cell Proliferation Induced by IL-2 and Neutralization by Human Common gamma Chain/ IL...
Flow Cytometry (FACS) image for anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-254) antibody (ABIN4899740) Detection of Common gamma Chain/IL-2 R gamma in Human PBMC by Flow Cytometry. Human p...