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anti-Mouse (Murine) IL3RA antibody for Intracellular Flow Cytometry

Recommended IL3RA Antibody (supplied by: Log in to see )

Antigen
Interleukin 3 Receptor, alpha (Low Affinity) (IL3RA) Antibodies
  • CD123
  • CDw123
  • Cyrl
  • hIL-3Ra
  • IL3R
  • IL3RAY
  • IL3RX
  • IL3RY
  • SUT-1
Reactivity
Mouse (Murine)
223
31
3
1
Host
Rat
137
95
16
1
Clonality
Monoclonal
Conjugate
This IL3RA antibody is conjugated to PE
23
22
21
13
6
5
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA (Detection), Intracellular Flow Cytometry (ICFC)
140
129
53
34
30
28
15
14
13
11
10
7
3
3
3
2
1
1
1
1
1
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Catalog No. ABIN2662992
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00086808536 ABIN2664182 FACS ICFC Rat IgG2a kappa Log in to see 5B11 5

Top referenced anti-IL3RA antibody for Intracellular Flow Cytometry

Similar anti-IL3RA Antibodies

Application / Reactivity Mouse (Murine)
ELISA 8 Antibodies
ELISA (Detection) 1 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 16 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunohistochemistry (IHC) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Western Blotting (WB) 13 Antibodies

General

Antigen Interleukin 3 Receptor, alpha (Low Affinity) (IL3RA) Antibodies
Reactivity Mouse (Murine)
(223), (31), (3), (1)
Host Rat
(137), (95), (16), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL3RA antibody is conjugated to PE
(23), (22), (21), (13), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA (Detection), Intracellular Flow Cytometry (ICFC)
(140), (129), (53), (34), (30), (28), (15), (14), (13), (11), (10), (7), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-IL3RA Antibody

Target Details IL3RA Application Details Handling References for anti-IL3RA Antibody (ABIN2662992) Images
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone 5B11
Isotype IgG2a kappa

Target Details IL3RA

Product Details anti-IL3RA Antibody Application Details Handling References for anti-IL3RA Antibody (ABIN2662992) Images back to top
Antigen
Alternative Name CD123 (IL3RA Antibody Abstract)
Background CD123 is a 70 kD α chain subunit of the IL-3 receptor (IL-3R α). It is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind IL-3 with low affinity but cannot transduce signals without association with additional protein partners. CD123 can complex with either the common β chain (CDw131) or the IL-3R β chain (AIC2A) to form high-affinity heterodimeric IL-3 receptors. CDw131 can complex with the α subunits of the mouse IL-3R, IL-5R and GM-CSFR to form high-affinity receptors, while the IL-3 R β subunit is specific for IL-3 but binds with low affinity. IL-3 binding to the receptor complex can induce proliferation and differentiation of hematopoietic cells. The 5B11 antibody does not block binding of IL-3 to the high affinity IL-3 receptor.
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL3RA Antibody Target Details IL3RA Handling References for anti-IL3RA Antibody (ABIN2662992) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL3RA Antibody Target Details IL3RA Application Details References for anti-IL3RA Antibody (ABIN2662992) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL3RA Antibody (ABIN2662992)

Product Details anti-IL3RA Antibody Target Details IL3RA Application Details Handling Images back to top
Background publications

Cervantes-Barragan, Züst, Weber, Spiegel, Lang, Akira, Thiel, Ludewig: "Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon." in: Blood, Vol. 109, Issue 3, pp. 1131-7, 2007

Ichihara, Hara, Takagi, Cho, Gorman, Miyajima: "Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene." in: The EMBO journal, Vol. 14, Issue 5, pp. 939-50, 1995

Mueller, Chen, Schwartz, Gorman, Kennedy: "Subset of CD4+ T cell clones expressing IL-3 receptor alpha-chains uses IL-3 as a cofactor in autocrine growth." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 7, pp. 3014-27, 1994

Miyajima, Mui, Ogorochi, Sakamaki: "Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5." in: Blood, Vol. 82, Issue 7, pp. 1960-74, 1993

Itoh, Yonehara, Schreurs, Gorman, Maruyama, Ishii, Yahara, Arai, Miyajima: "Cloning of an interleukin-3 receptor gene: a member of a distinct receptor gene family." in: Science (New York, N.Y.), Vol. 247, Issue 4940, pp. 324-7, 1990

Images

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Supplier Images
Flow Cytometry (FACS) image for anti-IL3RA antibody (Interleukin 3 Receptor, alpha (Low Affinity))  (PE) (ABIN2662992) anti-Interleukin 3 Receptor, alpha (Low Affinity) (IL3RA) antibody (PE)