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anti-Human IL4 Receptor antibody for Functional Studies

Recommended IL4 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin 4 Receptor (IL4R) Antibodies
  • CD124
  • IL-4RA
  • il-4ra
  • IL4
  • Il4r
  • IL4R
  • IL4RA
  • Il4ra
  • zgc:113063
Reactivity
Human
91
32
7
Host
Mouse
54
44
11
6
1
Clonality
Monoclonal
Conjugate
This IL4 Receptor antibody is un-conjugated
6
5
2
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS)
60
51
30
14
12
9
8
6
6
4
3
3
3
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN282320
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008762794 ABIN112606 EIA Func FACS IHC (p) WB Mouse IgG1 Extracellular Domain Log in to see 25463 (49-20)
0.0008762794 ABIN599796 Func FACS IHC (p) ELISA WB Mouse IgG1 Extracellular Domain Log in to see
0.0008762794 ABIN280629 Func FACS WB Mouse IgG1 kappa Log in to see X2-45-12

Top referenced anti-IL4 Receptor antibody for Functional Studies

Similar anti-IL4 Receptor Antibodies

Application / Reactivity Human
ELISA 40 Antibodies
ELISA (Capture) 3 Antibodies
ELISpot (Capture) (ELISPOT (Capture)) 2 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 24 Antibodies
Functional Studies (Func) 4 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 12 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies
Neutralization (Neut) 4 Antibodies
Western Blotting (WB) 54 Antibodies

General

Antigen Interleukin 4 Receptor (IL4R) Antibodies
Reactivity Human
(91), (32), (7)
Host Mouse
(54), (44), (11), (6), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL4 Receptor antibody is un-conjugated
(6), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Flow Cytometry (FACS)
(60), (51), (30), (14), (12), (9), (8), (6), (6), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-IL4 Receptor Antibody

Target Details IL4 Receptor Application Details Handling References for anti-IL4 Receptor Antibody (ABIN282320) Images
Specificity The X2/45-12 monoclonal antibody reacts with the human IL-4 receptor α chain. IL-4 receptor α chain (CD124) is crucial for the binding and signal transduction of IL-4. Both IL-4 and IL-13 use the IL-4 receptor α chain as their receptor component and activate many common signal pathways.
Characteristics The X2/45-12 monoclonal antibody reacts with the human IL-4 receptor α chain. IL-4 receptor α chain (CD124) is crucial for the binding and signal transduction of IL-4. Both IL-4 and IL-13 use the IL-4 receptor α chain as their receptor component and activate many common signal pathways.
Synonyms: Synonyms: Interleukin-4 Receptor alpha, IL-4Ra
Purification Affinity Purified
Endotoxin Level <0.001 ng endotoxin/μg
Grade Functional Grade
Clone X2-45-12
Isotype IgG1 kappa

Target Details IL4 Receptor

Product Details anti-IL4 Receptor Antibody Application Details Handling References for anti-IL4 Receptor Antibody (ABIN282320) Images back to top
Antigen
Alternative Name CD124 (IL4R Antibody Abstract)
Background IL-4 receptor alpha chain (CD124) is crucial for the binding and signal transduction of IL-4. Both IL-4 and IL-13 use the IL-4 receptor alpha chain as their receptor component and activate many common signal pathways.
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL4 Receptor Antibody Target Details IL4 Receptor Handling References for anti-IL4 Receptor Antibody (ABIN282320) Images back to top
Application Notes Applications reported: X2/45-12 has been reported for use in flow cytometric analysis. X2/45-12 has also been reported in neutralization of human IL-4 function.

Applications tested: The X2/45-12 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Restrictions For Research Use only

Handling

Product Details anti-IL4 Receptor Antibody Target Details IL4 Receptor Application Details References for anti-IL4 Receptor Antibody (ABIN282320) Images back to top
Concentration 1 mg/mL
Buffer aqueous buffer, no sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Use in sterile environment.
Storage 4 °C

References for anti-IL4 Receptor Antibody (ABIN282320)

Product Details anti-IL4 Receptor Antibody Target Details IL4 Receptor Application Details Handling Images back to top
Background publications

Tony, Shen, Reusch, Sebald: "Design of human interleukin-4 antagonists inhibiting interleukin-4-dependent and interleukin-13-dependent responses in T-cells and B-cells with high efficiency." in: European journal of biochemistry / FEBS, Vol. 225, Issue 2, pp. 659-65, 1994

Images

Product Details anti-IL4 Receptor Antibody Target Details IL4 Receptor Application Details Handling References for anti-IL4 Receptor Antibody (ABIN282320) back to top
Supplier Images
 image for anti-IL4 Receptor antibody (Interleukin 4 Receptor) (ABIN282320) anti-Interleukin 4 Receptor (IL4R) antibody