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anti-Human IL4 Receptor antibody for Intracellular Flow Cytometry

Recommended IL4 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin 4 Receptor (IL4R) Antibodies
  • CD124
  • IL-4RA
  • il-4ra
  • IL4
  • Il4r
  • IL4R
  • IL4RA
  • Il4ra
  • zgc:113063
Reactivity
Human
92
33
7
Host
Mouse
54
45
12
6
1
Clonality
Monoclonal
Conjugate
This IL4 Receptor antibody is conjugated to PE
5
5
2
1
1
1
1
1
1
1
1
1
Application
Intracellular Flow Cytometry (ICFC)
62
52
32
15
13
9
8
6
5
4
4
3
3
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN2662428
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008737065 ABIN2664183 ELISA (Capture) ELISPOT (Capture) ICFC IP Neut WB Mouse IgG2a kappa Log in to see G077F6 3
0.0008737065 ABIN2662429 ICFC PE Mouse IgG2a kappa Log in to see G077F6 3
0.0008737065 ABIN2664184 ELISA (Capture) ELISPOT (Capture) ICFC IP Neut WB Mouse IgG2a kappa Log in to see G077F6 3

Top referenced anti-IL4 Receptor antibody for Intracellular Flow Cytometry

Similar anti-IL4 Receptor Antibodies

Application / Reactivity Human
ELISA 40 Antibodies
ELISA (Capture) 3 Antibodies
ELISpot (Capture) (ELISPOT (Capture)) 2 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 24 Antibodies
Functional Studies (Func) 4 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 12 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies
Neutralization (Neut) 4 Antibodies
Western Blotting (WB) 54 Antibodies

General

Antigen Interleukin 4 Receptor (IL4R) Antibodies
Reactivity Human
(92), (33), (7)
Host Mouse
(54), (45), (12), (6), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL4 Receptor antibody is conjugated to PE
(5), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Intracellular Flow Cytometry (ICFC)
(62), (52), (32), (15), (13), (9), (8), (6), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-IL4 Receptor Antibody

Target Details IL4 Receptor Application Details Handling References for anti-IL4 Receptor Antibody (ABIN2662428) Images
Purification The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone G077F6
Isotype IgG2a kappa

Target Details IL4 Receptor

Product Details anti-IL4 Receptor Antibody Application Details Handling References for anti-IL4 Receptor Antibody (ABIN2662428) Images back to top
Antigen
Alternative Name CD124 (IL4R Antibody Abstract)
Background CD124, also known as the alpha subunit of IL-4R, is a 140 kD transmembrane glycoprotein. It associates with either the common γ-chain (CD132) to form the type I IL-4R complex, which specifically binds IL-4, or with IL-13Ra1 to form the type II IL-4R heterodimeric complex, which binds and transduces signals from either IL-4 or IL-13. A truncated form of IL-4Rα exists in the soluble form in biological fluids. CD124 is expressed on human B and T cells as well as a variety of other hematopoietic and non-hematopoietic cells and cell lines. In B cells, CD124 can bind with IL-4 and IL-13 to regulate IgE antibody production. In T cells, the type I IL-4R (IL-4R/gC) is mostly responsible for Th2 cell expansion by mediating IL-4-dependent activation of the transcription factors in hematopoietic cells. The type II IL-4R (IL-4R/IL-13Ra1) is the main route for non-hematopoietic cell responses to IL-4 or IL-13.
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL4 Receptor Antibody Target Details IL4 Receptor Handling References for anti-IL4 Receptor Antibody (ABIN2662428) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL4 Receptor Antibody Target Details IL4 Receptor Application Details References for anti-IL4 Receptor Antibody (ABIN2662428) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL4 Receptor Antibody (ABIN2662428)

Product Details anti-IL4 Receptor Antibody Target Details IL4 Receptor Application Details Handling Images back to top
Background publications

Gilmour, Lavender: "Control of IL-4 expression in T helper 1 and 2 cells." in: Immunology, Vol. 124, Issue 4, pp. 437-44, 2008

Kashiwada, Giallourakis, Pan, Rothman: "Immunoreceptor tyrosine-based inhibitory motif of the IL-4 receptor associates with SH2-containing phosphatases and regulates IL-4-induced proliferation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 11, pp. 6382-7, 2001

Hage, Sebald, Reinemer: "Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface." in: Cell, Vol. 97, Issue 2, pp. 271-81, 1999

Images

Product Details anti-IL4 Receptor Antibody Target Details IL4 Receptor Application Details Handling References for anti-IL4 Receptor Antibody (ABIN2662428) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-IL4 Receptor antibody (Interleukin 4 Receptor)  (PE) (ABIN2662428) anti-Interleukin 4 Receptor (IL4R) antibody (PE)