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Browse our IL4 Receptor Proteins (IL4R)

Full name:
Interleukin 4 Receptor Proteins (IL4R)
On www.antibodies-online.com are 29 Interleukin 4 Receptor (IL4R) Proteins from 12 different suppliers available. Additionally we are shipping IL4 Receptor Antibodies (117) and IL4 Receptor Kits (23) and many more products for this protein. A total of 181 IL4 Receptor products are currently listed.
Synonyms:
CD124, IL-4RA, IL4, Il4r, Il4ra, zgc:113063
list all proteins Gene Name GeneID UniProt
IL4R 3566 P24394
IL4R 25084 Q63257
IL4R 16190 P16382

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IL4 Receptor Proteins (IL4R) by Origin

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Top referenced IL4 Receptor Proteins

  1. Human IL4 Receptor Protein expressed in Human Cells - ABIN2002785 : Grabstein, Eisenman, Mochizuki, Shanebeck, Conlon, Hopp, March, Gillis: Purification to homogeneity of B cell stimulating factor. A molecule that stimulates proliferation of multiple lymphokine-dependent cell lines. in The Journal of experimental medicine 1986 (PubMed)
    Show all 6 references for ABIN2002785

  2. Rat (Rattus) IL4 Receptor Protein expressed in Human Cells - ABIN2009292 : Yokota, Arai, de Vries, Spits, Banchereau, Zlotnik, Rennick, Howard, Takebe, Miyatake: Molecular biology of interleukin 4 and interleukin 5 genes and biology of their products that stimulate B cells, T cells and hemopoietic cells. in Immunological reviews 1988 (PubMed)
    Show all 5 references for ABIN2009292

  3. Mouse (Murine) IL4 Receptor Protein expressed in Human Cells - ABIN2008742 : Kotowicz, Callard, Friedrich, Matthews, Klein: Biological activity of IL-4 and IL-13 on human endothelial cells: functional evidence that both cytokines act through the same receptor. in International immunology 1997 (PubMed)
    Show all 5 references for ABIN2008742

  4. Human IL4 Receptor Protein expressed in HEK-293 Cells - ABIN2181320 : Ikizawa, Yanagihara: Possible involvement of Shc in IL-4-induced germline epsilon transcription in a human B cell line. in Biochemical and biophysical research communications 2000 (PubMed)

More Proteins for IL4 Receptor Interaction Partners

Cow (Bovine) Interleukin 4 Receptor (IL4R) interaction partners

  1. IL-4 (show IL4 Proteins) may play a role in coordinating the adrenal response to inflammatory stress.

Zebrafish Interleukin 4 Receptor (IL4R) interaction partners

Human Interleukin 4 Receptor (IL4R) interaction partners

  1. Essential role of endocytosis for interleukin-4-receptor-mediated JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) signalling.

  2. analysis of IL-4 (show IL4 Proteins) and IL-13 (show IL13 Proteins) receptors in cancer biology and discussion of pre-clinical and clinical studies pertaining to recombinant immunotoxins designed to target these receptors [review]

  3. review of IL-4 (show IL4 Proteins) and IL-13 (show IL13 Proteins) receptor structure, receptor regulation, signaling and experimental therapeutics [review]

  4. Studies indicate significant association between the interleukin-4receptor (IL-4R) Q576R polymorphism and the risk of asthma in the Chinese Han population.

  5. Results illustrated that Saudi vitiligo (show MITF Proteins) patients showed significantly higher frequency of the IL-4R (Q551R A>G) homozygous GG variant (recessive mode) as compared with their respective controls

  6. IL-4RA-1902 A/A genotype has been associated with a reduced response to IL-4 (show IL4 Proteins) and has been found in 90% oral mucous membrane pemphigoid patient

  7. Genetic variants of NOS3, CD14, MMP3 and IL4R are implicated in the determination of VEGF expression and plasma levels.

  8. Study results have demonstrated, that of all investigated polymorphic variants of genes IL4 (show IL4 Proteins) (C-590T), IL4RA (150V), TNF (show TNF Proteins) (G-308A) and SLC11A1 (show SLC11A1 Proteins) (D543N) in patients with chronic liver diseases of various etiology

  9. IL4R mediates enhanced glucose and glutamine metabolism in breast cancer cells.

  10. Receptor trafficking may play an important role for the regulation of IL-4R-mediated JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) signaling.

Horse (Equine) Interleukin 4 Receptor (IL4R) interaction partners

  1. IL4R plays a role in some cases of recurrent airway obstruction.

Mouse (Murine) Interleukin 4 Receptor (IL4R) interaction partners

  1. Il4ra mRNA expression was significantly increased after stroke.

  2. functional synergy between Flt3 and IL-4R signaling is critical for Stat-mediated regulation of sterile gamma1 germ-line transcripts and CSR to IgG1

  3. Immunostaining and semiquantitative analysis revealed increased presence of IL4ra in the pulmonary vasculature of patients with connective tissue disease-associated PAH and Schistosoma-PAH compared with normal control subjects.

  4. data provide new insights into the molecular mechanisms governing IL-4Ralpha-induced responses, and may provide new therapeutic tools to target IL-4 (show IL4 Proteins) in allergy and asthma

  5. IL4R mediates enhanced glucose and glutamine metabolism in breast cancer cells.

  6. Data show that fibrillin-1 (FBN1 (show FBN1 Proteins)) modulates bone marrow mesenchymal stem cells (BMMSCs) lineage differentiation via IL4 receptor alpha/mTOR (show FRAP1 Proteins) protein signaling.

  7. we demonstrate that IL-13 (show IL13 Proteins)/IL-4Ralpha-dependent mechanisms are involved in tuberculosis-associated tissue pathology

  8. IL-13 (show IL13 Proteins) but not IL-4 (show IL4 Proteins) signaling via IL-4Ralpha protects mice from papilloma formation during DMBA/TPA (show PLAT Proteins) two-step skin carcinogenesis.

  9. TLR dependent antigen processing by IL-4Ralpha-responsive B cells producing IL-13 (show IL13 Proteins) contribute significantly to CD4 (show CD4 Proteins) T cell-mediated protective immunity against N. brasiliensis infection.

  10. Loa loa (show DYNC1H1 Proteins) exhibits a differential survival and development in different strains of cytokine or cytokine receptor (show LEPR Proteins) gene knockout mice with IL-4R and IL-5 (show IL5 Proteins) playing critical roles in the host resistance to L. loa (show DYNC1H1 Proteins) infection.

IL4 Receptor (IL4R) Protein Profile

Protein Summary

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with IL4 Receptor (IL4R)

  • interleukin 4 receptor (IL4R)
  • interleukin 4 receptor (il4r)
  • interleukin 4 receptor (LOC100220266)
  • interleukin 4 receptor (Il4r)
  • interleukin 4 receptor, alpha (Il4ra)
  • CD124 protein
  • IL-4RA protein
  • IL4 protein
  • Il4r protein
  • Il4ra protein
  • zgc:113063 protein

Protein level used designations for Interleukin 4 Receptor Proteins (IL4R)

interleukin 4 receptor alpha chain , interleukin-4 receptor alpha chain , interleukin-4 receptor subunit alpha , interleukin 4 receptor , IL-4RA-like protein 1 , il-4alpha , interleukin 4 receptor alpha , soluble IL-4 receptor alpha , interleukin-4 receptor subunit alpha-like , IL-4 receptor subunit alpha , IL4R nirs variant 1 , IL-4R subunit alpha , IL-4R-alpha , IL-4RA , interleukin 4 receptor, alpha , interleukin 4 tv3 , interleukin 4 tv5 , interleukin-4 receptor alpha-chain , IL-4 receptor alpha chain

GENE ID SPECIES
404154 Bos taurus
416585 Gallus gallus
454005 Pan troglodytes
489957 Canis lupus familiaris
503594 Danio rerio
705404 Macaca mulatta
100220266 Taeniopygia guttata
100412639 Callithrix jacchus
100449812 Pongo abelii
100606206 Nomascus leucogenys
3566 Homo sapiens
25084 Rattus norvegicus
397614 Sus scrofa
791252 Equus caballus
16190 Mus musculus
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