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anti-Rat (Rattus) IL5 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended IL5 Antibody (supplied by: Log in to see )

Antigen
Interleukin 5 (IL5) Antibodies
  • EDF
  • IL-5
  • Il-5
  • IL5
  • Pro-TRH
  • TRF
Reactivity
Human, Mouse (Murine), Rat (Rattus)
167
130
19
17
17
2
1
1
1
1
Host
Rabbit
128
94
19
2
Clonality
Polyclonal
Conjugate
This IL5 antibody is un-conjugated
42
12
5
5
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
124
120
92
34
17
14
11
11
10
9
9
9
8
6
5
4
4
4
4
1
1
Supplier
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Catalog No. ABIN498493
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN674904 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN674913 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN674906 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN446956 IHC (p) IHC WB Rabbit Log in to see Polyclonal 1

Top referenced anti-IL5 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-IL5 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 91 Antibodies 55 Antibodies 9 Antibodies
Neutralization (Neut) 13 Antibodies 23 Antibodies
Intracellular Staining (ICS) 6 Antibodies 4 Antibodies
Immunoprecipitation (IP) 4 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies 5 Antibodies 5 Antibodies
Immunohistochemistry (IHC) 16 Antibodies 5 Antibodies 4 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies

General

Antigen Interleukin 5 (IL5) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(167), (130), (19), (17), (17), (2), (1), (1), (1), (1)
Host Rabbit
(128), (94), (19), (2)
Clonality
Polyclonal
Conjugate This IL5 antibody is un-conjugated
(42), (12), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(124), (120), (92), (34), (17), (14), (11), (11), (10), (9), (9), (9), (8), (6), (5), (4), (4), (4), (4), (1), (1)
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Product Details anti-IL5 Antibody

Target Details IL5 Application Details Handling Images
Specificity This antibody detects endogenous levels of IL-5 protein. (region surrounding Ser92)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details IL5

Product Details anti-IL5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Interleukin-5 / IL5 (IL5 Antibody Abstract)
Background Interleukin 5 (IL-5) is a soluble T cell-derived factor, also known as T cellreplacing factor (TRF), that induces B cell and eosinophil growth and differentiation. IL-5 exerts its biological activity through the IL-5 receptor (IL-5R), which is composed of two chains: an alpha chain that binds IL-5 with low affinity and a beta chain that does not bind IL-5, but together with the IL-5 alpha chain, constitutes the high affinity IL-5 receptor. The cytoplasmic domain of both the alpha and beta chains is essential for signal transduction. Specifically, the membraneproximal proline-rich sequence of the cytoplasmic domain of the IL-5R receptor alpha subunit, IL-5Ralpha, is critical for the IL-5 induced proliferative response, expression of nuclear protooncogenes and tyrosine phosphorylation of cellular proteins, such as JAK1 and JAK2. Alternative splicing of the IL-5Ralpha gene produces several isoforms, including a membraneanchored isoform and a soluble isoform. The soluble isoform competes with IL-5 for binding to IL-5R and inhibits IL-5-mediated receptor activation and inflammatory mediator production, and, therefore, may be useful in treating asthma.Synonyms: B-cell differentiation factor I, Eosinophil differentiation factor, IL-5, T-cell replacing factor, TRF
Molecular Weight approx. 45 kDa
Gene ID 3567
NCBI Accession NP_000870
UniProt P05113
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL5 Antibody Target Details IL5 Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL5 Antibody Target Details IL5 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-IL5 Antibody Target Details IL5 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-IL5 antibody (Interleukin 5) (ABIN498493) Immunohistochemistry (IHC) analyzes of IL-5 antibody in paraffin-emb...
Western Blotting (WB) image for anti-IL5 antibody (Interleukin 5) (ABIN498493) Western blot (WB) analysis of IL-5 antibody in extracts from HT-29 cells.