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anti-Human IL5RA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended IL5RA Antibody (supplied by: Log in to see )

Antigen
Interleukin 5 Receptor, alpha (IL5RA) Antibodies
  • MGC86517
  • IL5RA
  • il5r
  • cdw125
  • hsil5r3
  • gpIL-5ra
  • CD125
  • CDw125
  • HSIL5R3
  • IL5R
  • Il5r
  • interleukin 5 receptor, alpha
  • il5ra
  • IL5RA
  • Il5ra
Reactivity
Human, Mouse (Murine)
88
37
25
2
2
2
2
2
2
1
Host
Rabbit
82
9
1
Clonality
Polyclonal
Conjugate
This IL5RA antibody is un-conjugated
7
6
6
5
4
4
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
68
44
30
22
13
5
2
2
2
1
Supplier
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Catalog No. ABIN498570
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN651428 FACS IHC (p) WB Rabbit Ig AA 49-76, N-Term Log in to see Polyclonal
1 ABIN747842 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN747835 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN747833 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
1 ABIN1812126 FACS IHC (p) WB Rabbit AA 49-76 Log in to see Polyclonal

Top referenced anti-IL5RA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-IL5RA Antibodies

Application / Reactivity Human Mouse (Murine)
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 1 Antibodies
Western Blotting (WB) 64 Antibodies 17 Antibodies
Neutralization (Neut) 1 Antibodies
Immunoprecipitation (IP) 1 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies 6 Antibodies
Immunohistochemistry (IHC) 28 Antibodies 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies 13 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 1 Antibodies
Flow Cytometry (FACS) 22 Antibodies 3 Antibodies

General

Antigen Interleukin 5 Receptor, alpha (IL5RA) Antibodies
Reactivity Human, Mouse (Murine)
(88), (37), (25), (2), (2), (2), (2), (2), (2), (1)
Host Rabbit
(82), (9), (1)
Clonality
Polyclonal
Conjugate This IL5RA antibody is un-conjugated
(7), (6), (6), (5), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(68), (44), (30), (22), (13), (5), (2), (2), (2), (1)
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Product Details anti-IL5RA Antibody

Target Details IL5RA Application Details Handling Images
Specificity This antibody detects endogenous levels of IL-5Ralpha protein. (region surrounding Lys68)
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Affinity Chromatography using epitope-specific immunogen

Target Details IL5RA

Product Details anti-IL5RA Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD125 / IL5RA (IL5RA Antibody Abstract)
Background Interleukin 5 (IL-5) is a soluble T cell-derived factor, also known as T cellreplacing factor (TRF), that induces B cell and eosinophil growth and differentiation. IL-5 exerts its biological activity through the IL-5 receptor (IL-5R), which is composed of two chains: an alpha chain that binds IL-5 with low affinity and a beta chain that does not bind IL-5, but together with the IL-5 alpha chain, constitutes the high affinity IL-5 receptor. The cytoplasmic domain of both the alpha and beta chains is essential for signal transduction. Specifically, the membraneproximal proline-rich sequence of the cytoplasmic domain of the IL-5R receptor alpha subunit, IL-5Ralpha, is critical for the IL-5 induced proliferative response, expression of nuclear protooncogenes and tyrosine phosphorylation of cellular proteins, such as JAK1 and JAK2. Alternative splicing of the IL-5Ralpha gene produces several isoforms, including a membraneanchored isoform and a soluble isoform. The soluble isoform competes with IL-5 for binding to IL-5R and inhibits IL-5-mediated receptor activation and inflammatory mediator production, and, therefore, may be useful in treating asthma.Synonyms: IL-5R-alpha, IL5 Receptor alpha, Interleukin-5 receptor subunit alpha
Gene ID 3568
NCBI Accession NP_000555
UniProt Q01344
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL5RA Antibody Target Details IL5RA Handling Images back to top
Application Notes Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL5RA Antibody Target Details IL5RA Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-IL5RA Antibody Target Details IL5RA Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-IL5RA antibody (Interleukin 5 Receptor, alpha) (ABIN498570) Immunohistochemistry analysis of CD125 / IL5RA Antibody in Paraffin-Embedded H...