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anti-Mouse (Murine) IL7R antibody for Functional Studies

Recommended IL7R Antibody (supplied by: Log in to see )

Antigen
Interleukin 7 Receptor (IL7R) Antibodies
  • CD127
  • CDW127
  • IL-7R-alpha
  • IL-7RA
  • IL-7Ralpha
  • IL7R
  • IL7RA
  • ILRA
Reactivity
Mouse (Murine)
225
187
27
3
Host
Rat
152
105
97
13
2
Clonality
Monoclonal
Conjugate
This IL7R antibody is un-conjugated
26
24
22
16
15
14
10
9
9
7
7
6
6
5
5
5
5
5
5
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS)
169
156
65
64
52
22
13
12
11
9
5
4
4
4
3
3
2
2
2
1
1
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Available images

Catalog No. ABIN282324
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008774256 ABIN280631 Func FACS IHC (fro) IP Rat IgG2a kappa Log in to see A7R34
0.0008774256 ABIN2567190 Func FACS IP IHC Rat IgG2a kappa Log in to see A7R34

Similar anti-IL7R Antibodies

Application / Reactivity Mouse (Murine)
Biochemical Assay (BCA) 1 Antibodies
Blocking Reagent (BR) 3 Antibodies
ELISA 38 Antibodies
ELISA (Capture) 2 Antibodies
ELISA (Detection) 4 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 87 Antibodies
Functional Studies (Func) 3 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 33 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 32 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Intracellular Flow Cytometry (ICFC) 12 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies
Western Blotting (WB) 95 Antibodies

General

Antigen Interleukin 7 Receptor (IL7R) Antibodies
Reactivity Mouse (Murine)
(225), (187), (27), (3)
Host Rat
(152), (105), (97), (13), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL7R antibody is un-conjugated
(26), (24), (22), (16), (15), (14), (10), (9), (9), (7), (7), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Flow Cytometry (FACS)
(169), (156), (65), (64), (52), (22), (13), (12), (11), (9), (5), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1)
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Product Details anti-IL7R Antibody

Target Details IL7R Application Details Handling Images
Specificity The A7R34 monoclonal antibody reacts with mouse CD127, the high affinity alpha subunit of the mouse IL-7 receptor. IL-7 receptor alpha chain is expressed by immature B cells in the bone marrow, double-negative (CD4-CD8-), single-positive (CD4+ and CD8+), but not double-positive (CD4+CD8+) thymocytes. In the periphery, mature T cells express CD127 at low level. A7R34 inhibits binding of IL-7 to its receptor and has been used in in vivo and in vitro studies to elucidate the role of IL-7 in T and B cell development and activation. Binding of A7R34 blocks the binding of SB/199, another antibody which recognizes mouse CD127.
Characteristics The A7R34 monoclonal antibody reacts with mouse CD127, the high affinity alpha subunit of the mouse IL-7 receptor. IL-7 receptor alpha chain is expressed by immature B cells in the bone marrow, double-negative (CD4-CD8-), single-positive (CD4+ and CD8+), but not double-positive (CD4+CD8+) thymocytes. In the periphery, mature T cells express CD127 at low level. A7R34 inhibits binding of IL-7 to its receptor and has been used in in vivo and in vitro studies to elucidate the role of IL-7 in T and B cell development and activation. Binding of A7R34 blocks the binding of SB/199, another antibody which recognizes mouse CD127.
Synonyms: Synonyms: Interleukin-7 Receptor alpha
Purification Affinity Purified
Endotoxin Level <0.001 ng endotoxin/μg
Grade Functional Grade
Clone A7R34
Isotype IgG2a kappa

Target Details IL7R

Product Details anti-IL7R Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD127 (IL7R Antibody Abstract)
Background IL-7 receptor alpha chain is expressed by immature B cells in the bone marrow, double-negative (CD4-/CD8-), single-positive (CD4+ and CD8+), but not double-positive (CD4+/CD8+) thymocytes. In the periphery, mature T cells express CD127 at low level. A7R34 inhibits binding of IL-7 to its receptor and has been used in in vivo and in vitro studies to elucidate the role of IL-7 in T and B cell development and activation. Binding of A7R34 blocks the binding of SB/199, another antibody which recognizes mouse CD127.
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL7R Antibody Target Details IL7R Handling Images back to top
Application Notes Applications reported: The A7R34 antibody has been reported for use in flow cytometric analysis. It has also been reported in blocking of IL-7 binding in functional studies.

Applications tested: The A7R34 antibody has been tested by flow cytometric analysis of mouse thymocyte and splenocyte suspensions. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Restrictions For Research Use only

Handling

Product Details anti-IL7R Antibody Target Details IL7R Application Details Images back to top
Concentration 1 mg/mL
Buffer aqueous buffer, no sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Use in sterile environment.
Storage 4 °C

Images

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling back to top
Supplier Images
 image for anti-IL7R antibody (Interleukin 7 Receptor) (ABIN282324) Staining of C57Bl/6 splenocytes with 0.5 µg of FG Purified Rat IgG2a Iso Cntrl (ABIN2...