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|Application / Reactivity||Human|
|Blocking Antibody (Inhibition)||2 Antibodies|
|Blocking Reagent (BR)||2 Antibodies|
|Depletion (Dep)||2 Antibodies|
|Enzyme Immunoassay (EIA)||4 Antibodies|
|Flow Cytometry (FACS)||19 Antibodies|
|Functional Studies (Func)||2 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies|
|Immunofluorescence (IF)||4 Antibodies|
|Immunohistochemistry (IHC)||19 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||1 Antibodies|
|Immunoprecipitation (IP)||2 Antibodies|
|Intracellular Staining (ICS)||4 Antibodies|
|Mass Cytometry (CyTOF)||2 Antibodies|
|Neutralization (Neut)||13 Antibodies|
|Radioimmunoassay (RIA)||1 Antibodies|
|Western Blotting (WB)||56 Antibodies|
|Antigen||Interleukin 9 (IL9) Antibodies|
|Conjugate||This IL9 antibody is conjugated to PE-Cy7 Alternatives|
Flow Cytometry (FACS)
|8 references available|
|Supplier||Log in to see|
Product Details anti-IL9 AntibodyTarget Details IL9 Application Details Handling References for anti-IL9 Antibody (ABIN2659377) Images
|Purification||The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.|
Target Details IL9Product Details anti-IL9 Antibody Application Details Handling References for anti-IL9 Antibody (ABIN2659377) Images back to top
|Alternative Name||IL-9 (IL9 Antibody Abstract)|
|Background||IL-9 is a potent, T cell-derived, T cell growth factor which can also enhance mast cell activity and IL-3- or IL-4- dependent proliferation of bone marrow-derived mast cells. IL-9 synergizes with erythropoietin to promote erythroid colony formation. IL-9 has also been reported to protect human T cells from apoptosis induced by IL-2 withdrawal. IL-9 is upregulated in human eosinophils by TNF-α and IL1-β. IL-9 has been reported to downregulate the oxidative burst in activated human alveolar macropahges and induce TGF-β production. The MH9A4 antibody reacts with human IL-9. The MH9A4 antibody can neutralize the bioactivity of natural or recombinant IL-9.|
|Research Area||Cytokines, Immunology, Virology, Inflammation, Cancer|
|Pathways||JAK-STAT Signaling, TCR Signaling|
Application DetailsProduct Details anti-IL9 Antibody Target Details IL9 Handling References for anti-IL9 Antibody (ABIN2659377) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL9 Antibody Target Details IL9 Application Details References for anti-IL9 Antibody (ABIN2659377) Images back to top
|Buffer||Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Protect from prolonged exposure to light. Do not freeze.|
|Storage Comment||The antibody solution should be stored undiluted between 2°C and 8°C.|
References for anti-IL9 Antibody (ABIN2659377)Product Details anti-IL9 Antibody Target Details IL9 Application Details Handling Images back to top
Lozano, Dominguez-Villar, Kuchroo et al.: "The TIGIT/CD226 axis regulates human T cell function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 8, pp. 3869-75, 2012 (PubMed).
Chang, Sehra, Goswami et al.: "The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation." in: Nature immunology, Vol. 11, Issue 6, pp. 527-34, 2010 (PubMed).
Chen, Petrus, Bryant et al.: "Induction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells by a paracrine mechanism." in: Blood, Vol. 111, Issue 10, pp. 5163-72, 2008 (PubMed).
Faulkner, Turner, Kamgno et al.: "Age- and infection intensity-dependent cytokine and antibody production in human trichuriasis: the importance of IgE." in: The Journal of infectious diseases, Vol. 185, Issue 5, pp. 665-72, 2002 (PubMed).
Jenmalm, Van Snick, Cormont et al.: "Allergen-induced Th1 and Th2 cytokine secretion in relation to specific allergen sensitization and atopic symptoms in children." in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 31, Issue 10, pp. 1528-35, 2001 (PubMed).
Renauld, Houssiau, Louahed et al.: "Interleukin-9." in: Advances in immunology, Vol. 54, pp. 79-97, 1993 (PubMed).
Quesniaux: "Interleukins 9, 10, 11 and 12 and kit ligand: a brief overview." in: Research in immunology, Vol. 143, Issue 4, pp. 385-400, 1992 (PubMed).
Yang: "Human interleukin-9: a new cytokine in hematopoiesis." in: Leukemia & lymphoma, Vol. 8, Issue 6, pp. 441-7, 1993 (PubMed).
ImagesProduct Details anti-IL9 Antibody Target Details IL9 Application Details Handling References for anti-IL9 Antibody (ABIN2659377) back to top