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Browse our anti-JAK1 (JAK1) Antibodies

Full name:
anti-Janus Kinase 1 Antibodies (JAK1)
On www.antibodies-online.com are 126 Janus Kinase 1 (JAK1) Antibodies from 23 different suppliers available. Additionally we are shipping JAK1 Kits (16) and JAK1 Proteins (12) and many more products for this protein. A total of 160 JAK1 products are currently listed.
Synonyms:
AA960307, C130039L05Rik, jak1, JAK1A, JAK1B, JNK, JNK1, JTK3, wu:fb93e10
list all antibodies Gene Name GeneID UniProt
JAK1 3716 P23458
JAK1 16451  
JAK1 84598  

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anti-Human JAK1 Antibodies:

anti-Mouse (Murine) JAK1 Antibodies:

anti-Rat (Rattus) JAK1 Antibodies:

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Top referenced anti-JAK1 Antibodies

  1. Chicken Monoclonal JAK1 Primary Antibody for IF, IP - ABIN967842 : Blesofsky, Mowen, Arduini, Baker, Murphy, Bowtell, David: Regulation of STAT protein synthesis by c-Cbl. in Oncogene 2001 (PubMed)
    Show all 5 references for ABIN967842

  2. Human Polyclonal JAK1 Primary Antibody for IHC, WB - ABIN362146 : Zheng, Hu, Quinn, Wang: Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography. in Molecular & cellular proteomics : MCP 2005 (PubMed)
    Show all 4 references for ABIN362146

  3. Human Polyclonal JAK1 Primary Antibody for IHC, WB - ABIN362702 : Wang, Griffin, Small, Thompson: Mechanism of Janus kinase 3-catalyzed phosphorylation of a Janus kinase 1 activation loop peptide. in Archives of biochemistry and biophysics 2003 (PubMed)
    Show all 3 references for ABIN362702

  4. Human Polyclonal JAK1 Primary Antibody for WB - ABIN265196 : Huang, Lin, Chen, Chang: Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells. in Journal of cellular biochemistry 2005 (PubMed)

  5. Human Polyclonal JAK1 Primary Antibody for IF, IHC - ABIN1533664 : Lee, Strunk, Spritz: A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes. in Oncogene 1993 (PubMed)

More Antibodies against JAK1 Interaction Partners

Pig (Porcine) Janus Kinase 1 (JAK1) interaction partners

  1. Data indicate that transmissible gastroenteritis virus (TGEV) infection activates the janus kinase signal transducer and activator of the transcription 1 (JAK (show JAK3 Antibodies)-STAT1 (show STAT1 Antibodies)) signaling pathway.

  2. Data show that proinflammatory cytokines induction was ERK1/2 (show MAPK1/3 Antibodies) and JNK1 (show MAPK8 Antibodies)/2 dependent.

  3. These data suggest that the p38 (show MAPK14 Antibodies) and JNK (show MAPK8 Antibodies) signaling pathways play pivotal roles in PRRSV replication and may regulate immune responses during virus infection.

  4. based on the data, we can conclude that JNK (show MAPK8 Antibodies) plays an active role in fragmentation of pig oocytes and that p38 MAPK (show MAPK14 Antibodies) is not involved in this process

  5. Retinal ischemia-reperfusion alters expression of mitogen-activated protein kinases, particularly ERK1/2 (show MAPK1/3 Antibodies), in the neuroretina and retinal arteries.

  6. PP2A (show PPP2R2B Antibodies) and AIP1 (show PDCD6IP Antibodies) cooperatively induce activation of ASK1 (show MAP3K5 Antibodies)-JNK (show MAPK8 Antibodies) signaling and vascular endothelial cell apoptosis.

  7. Phorbol 12-myristate 13-acetate activation of ERK (show MAPK1 Antibodies) and JNK (show MAPK8 Antibodies) signaling is relevant in the regulation of gene expression during follicular development, ovulation, and luteinization.

Rabbit Janus Kinase 1 (JAK1) interaction partners

  1. This is the first report of the genetic polymorphisms of the JAK1 and STAT3 (show STAT3 Antibodies) genes and their associations with the incidence of non-specific digestive disorder in rabbits.

Human Janus Kinase 1 (JAK1) interaction partners

  1. JAK1 rs310241 C-related genotype and allele are involved in AR susceptibility, making them potentially useful genetic biomarkers for allergic rhinitis susceptibility in the Chinese Han population.

  2. Data show that astaxanthin functions as a potent inhibitor of A549 lung cancer cell growth by targeting Janus kinase 1 a(JAK1)/STAT3 (show STAT3 Antibodies) transcription factor (STAT3 (show STAT3 Antibodies)) signaling pathway.

  3. Genetic Variation in the JAK1 gene is associated with distal Colonic Disease, Stricturing Disease Behavior.

  4. Activating JAK1 mutation may predict the sensitivity of JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies) inhibition in hepatocellular carcinoma.

  5. Foot-and-mouth disease virus VP3 interacted with JAK1/2, degraded JAK1, and inhibited the tyrosine phosphorylation, dimerization and nuclear accumulation of STAT1 (show STAT1 Antibodies).

  6. Data suggest that targeting both TGF-beta (show TGFB1 Antibodies) and Janus kinase 1 (JAK1) signaling could be explored therapeutically in pancreatic ductal adenocarcinomas (PDACs) patients whose cancers exhibit an angiogenesis gene signature.

  7. When association tests were applied to data from the Diabetes Heart Study, it found exome variants of POMGNT1 (show POMGNT1 Antibodies) and JAK1 genes were associated with type 2 diabetes.

  8. Studies indicate that Janus kinase 1 (JAK1) inhibition leads to depression in inflammatory cytokine expression associated with MF-related constitutional symptoms.

  9. Mutations leading to constitutive active gp130 (show IL6ST Antibodies)/JAK1/STAT3 (show STAT3 Antibodies) pathway.

  10. Increased expression of SgK223 occurs in PDAC, and overexpression of SgK223 in pancreatic ductal epithelial cells promotes acquisition of a migratory and invasive phenotype through enhanced JAK1/Stat3 (show STAT3 Antibodies) signaling

Mouse (Murine) Janus Kinase 1 (JAK1) interaction partners

  1. Data indicate thar Janus kinase 1 (Jak1) degradation is dependent on Nedd4 family interacting proteins Ndfip1 (show NDFIP1 Antibodies)/Ndfip2 (show NDFIP2 Antibodies).

  2. Experiments implicate JAK1/3 signaling in cancer- and myocardial infarction-mediated diaphragm weakness in mice.

  3. JAK1/JAK2 (show JAK2 Antibodies) inhibition of graft-versus-host disease was associated with the modulation of chemokine receptor (show CCR1 Antibodies) expression, which may have been one factor in the reduced infiltration of donor T cells in graft-versus-host disease target organs.

  4. -1 promotes IFN-alpha (show IFNA Antibodies)-induced autophagy via the JAK1-STAT1 (show STAT1 Antibodies) signaling.

  5. Zn deficiency enhances the acute phase response and particularly the JAK-STAT3 pathway, resulting in increased serum amyloid A production.

  6. JAK1 and JAK3 (show JAK3 Antibodies) mutants cooperate in T-cell transformation

  7. Data suggest thatthat pharmacologic targeting of excessively activated wild-type Jak (show JAK3 Antibodies) kinases Jak1/2 affords therapeutic suppression of inflammation-associated gastrointestinal cancers progression in vivo.

  8. Jak3 (show JAK3 Antibodies) pseudokinase mutants require JAK1 for their transforming potential causing T-cell acute lymphoblastic leukemia in a mouse model.

  9. In cellular assays, SAR (show SRL Antibodies)-20347 dose dependently (1 nM-10 muM) inhibited JAK1- and/or TYK2 (show TYK2 Antibodies)-dependent signaling from the IL-12 (show IL12A Antibodies)/IL-23 (show IL23A Antibodies), IL-22 (show IL22 Antibodies), and IFN-alpha (show IFNA Antibodies) receptors.

  10. Disruption of PERK (show EIF2AK3 Antibodies) abrogates endoplasmic reticulum stress-induced activation of STAT3 (show STAT3 Antibodies) via JAK1.

Zebrafish Janus Kinase 1 (JAK1) interaction partners

  1. JAK1 activating mutants are insufficient to drive hepatocellular carcinoma development in vivo.

JAK1 Antigen Profile

Antigen Summary

Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs.

Alternative names and synonyms associated with JAK1

  • Janus kinase 1 (JAK1) antibody
  • mitogen-activated protein kinase 8 (MAPK8) antibody
  • Tyrosine-protein kinase Jak1 (jak1) antibody
  • Janus kinase 1 (jak1) antibody
  • Janus kinase 1 (Jak1) antibody
  • AA960307 antibody
  • C130039L05Rik antibody
  • jak1 antibody
  • JAK1A antibody
  • JAK1B antibody
  • JNK antibody
  • JNK1 antibody
  • JTK3 antibody
  • wu:fb93e10 antibody

Protein level used designations for anti-Janus Kinase 1 (JAK1) Antibodies

Janus kinase 1 (a protein tyrosine kinase) , protein tyrosine kinase , tyrosine kinase JAK1 , tyrosine-protein kinase JAK1 , janus kinase 1 , Janus kinase 1 , Tyrosine-protein kinase Jak1 , tyrosine-protein kinase JAK1-like , JAK-1 , Janus protein tyrosine kinase 1 , etID309794.6 , fb93e10 , jak-1 , jak1 kinase

GENE ID SPECIES
442952 Canis lupus familiaris
395681 Gallus gallus
396610 Sus scrofa
677689 Macaca mulatta
697808 Macaca mulatta
743373 Pan troglodytes
100031307 Monodelphis domestica
100286690 Salmo salar
100352594 Oryctolagus cuniculus
100385835 Callithrix jacchus
100433477 Pongo abelii
100473460 Ailuropoda melanoleuca
100559328 Anolis carolinensis
3716 Homo sapiens
16451 Mus musculus
84598 Rattus norvegicus
397202 Sus scrofa
537201 Bos taurus
30280 Danio rerio
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