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anti-Rat (Rattus) JAK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended JAK2 Antibody (supplied by: Log in to see )

Antigen
Janus Kinase 2 (JAK2) Antibodies
  • JAK2bCA
  • jak2
  • JTK10
  • THCYT3
  • AI504024
  • C81284
  • Fd17
  • JAK-2
  • Janus kinase 2b
  • Janus kinase 2
  • tyrosine-protein kinase JAK2-like
  • jak2b
  • JAK2
  • Jak2
  • LOC100051487
Reactivity
Human, Mouse (Murine), Rat (Rattus)
254
166
153
8
7
6
6
2
1
1
1
Host
Rabbit
246
19
5
Clonality
Polyclonal
Conjugate
This JAK2 antibody is un-conjugated
9
6
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
174
118
97
27
27
25
17
11
9
3
3
Supplier
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Catalog No. ABIN265487
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN318056 EIA IHC (p) Rabbit pTyr1007 Log in to see Polyclonal
1 ABIN740955 IF (p) IHC (p) WB Rabbit IgG pTyr1007, pTyr1008 Log in to see Polyclonal 1
1 ABIN319397 IHC (p) Rabbit Tyr570 Log in to see Polyclonal
1 ABIN729688 IF (p) IHC (p) WB Rabbit IgG AA 623-666 Log in to see Polyclonal
1 ABIN4327879 IHC IHC (p) WB Rabbit pTyr1007 Log in to see Polyclonal
1 ABIN729697 IHC (p) WB HRP Rabbit IgG AA 623-666 Log in to see Polyclonal
1 ABIN729690 IHC (p) WB Biotin Rabbit IgG AA 623-666 Log in to see Polyclonal
1 ABIN740964 IHC (p) WB HRP Rabbit IgG pTyr1007, pTyr1008 Log in to see Polyclonal
1 ABIN740957 IHC (p) WB Biotin Rabbit IgG pTyr1007, pTyr1008 Log in to see Polyclonal
1 ABIN4327881 IHC IHC (p) Rabbit pTyr1007 Log in to see Polyclonal
1 ABIN4327885 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN742853 IF (p) IHC (p) WB Rabbit IgG pTyr221 Log in to see Polyclonal
1 ABIN4327882 IHC IHC (p) WB Rabbit Log in to see Polyclonal

Top referenced anti-JAK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-JAK2 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 164 Antibodies 104 Antibodies 89 Antibodies
Immunoprecipitation (IP) 4 Antibodies 4 Antibodies 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 25 Antibodies 16 Antibodies 14 Antibodies
Immunohistochemistry (IHC) 110 Antibodies 78 Antibodies 78 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 27 Antibodies 27 Antibodies 27 Antibodies
Immunofluorescence (IF) 27 Antibodies 20 Antibodies

General

Antigen Janus Kinase 2 (JAK2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(254), (166), (153), (8), (7), (6), (6), (2), (1), (1), (1)
Host Rabbit
(246), (19), (5)
Clonality
Polyclonal
Conjugate This JAK2 antibody is un-conjugated
(9), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(174), (118), (97), (27), (27), (25), (17), (11), (9), (3), (3)
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Product Details anti-JAK2 Antibody

Target Details JAK2 Application Details Handling Images
Specificity This antibody detects endogenous levels of JAK2 protein. (region surrounding Leu1001)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Purity > 95 % pure by SDS-PAGE

Target Details JAK2

Product Details anti-JAK2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Tyrosine-Protein Kinase JAK2 (JAK2 Antibody Abstract)
Background Jak2 (Janus Kinase 2) belongs to the emerging family of non-receptor janus tyrosine kinases, which regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Immunological stimuli, such as interferons and cytokines, induce recruitment of STAT transcription factors to cytokine receptor-associated Jak2. Jak2 then phosphorylates proximal STAT factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription. The canonical Jak-STAT pathway is integral to maintaining a normal immune system by stimulating proliferation, differentiation, survival, and host resistance to pathogens. Altering Jak-STAT signaling to reduce cytokine induced pro-inflammatory responses represents an attractive target for anti-inflammatory therapies.Synonyms: JAK-2, Janus kinase 2
Molecular Weight approx. 125 kDa
Gene ID 3717
NCBI Accession NP_004963
UniProt O60674
Research Area Signaling, Cytokines, Receptors, Kinases/Phosphatases
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus

Application Details

Product Details anti-JAK2 Antibody Target Details JAK2 Handling Images back to top
Application Notes ELISA: 1: 10000approx. 1: 20000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-JAK2 Antibody Target Details JAK2 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

Product Details anti-JAK2 Antibody Target Details JAK2 Application Details Handling back to top
Supplier Images
 image for anti-JAK2 antibody (Janus Kinase 2) (ABIN265487) anti-Janus Kinase 2 (JAK2) antibody