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anti-Cow (Bovine) JAK3 antibody for Western Blotting

Recommended JAK3 Antibody (supplied by: Log in to see )

Antigen
Tyrosine-Protein Kinase JAK3 (JAK3) Antibodies
  • fae
  • JAK
  • JAK-3
  • JAK3_HUMAN
  • JAKL
  • L-JAK
  • LJAK
  • RATJAK3
  • wil
Epitope
Middle Region
15
15
13
13
11
8
7
7
5
2
2
2
2
2
2
2
1
1
1
1
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
79
55
39
2
1
1
1
1
1
Host
Rabbit
61
22
Clonality
Polyclonal
Conjugate
This JAK3 antibody is un-conjugated
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
Application
Western Blotting (WB)
47
36
23
13
10
10
7
5
2
1
1
1
1
Supplier
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Catalog No. ABIN2785645
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.12303223 ABIN2785644 WB Rabbit N-Term Log in to see Polyclonal

Top referenced anti-JAK3 antibody for Western Blotting

Similar anti-JAK3 Antibodies

Application / Reactivity Human Rat (Rattus) Mouse (Murine) Chicken Cow (Bovine) Dog (Canine) Pig (Porcine)
Western Blotting (WB) 47 Antibodies 21 Antibodies 34 Antibodies 1 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies 10 Antibodies 9 Antibodies
Immunohistochemistry (IHC) 11 Antibodies 11 Antibodies 9 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies

General

Antigen Tyrosine-Protein Kinase JAK3 (JAK3) Antibodies
Epitope Middle Region
(15), (15), (13), (13), (11), (8), (7), (7), (5), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(79), (55), (39), (2), (1), (1), (1), (1), (1)
Host Rabbit
(61), (22)
Clonality
Polyclonal
Conjugate This JAK3 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Western Blotting (WB)
(47), (36), (23), (13), (10), (10), (7), (5), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-JAK3 Antibody

Target Details JAK3 Application Details Handling References for anti-JAK3 Antibody (ABIN2785645) Images
Blocking Peptide Blocking peptide for this product available: ABIN978683
Sequence KLLPLDKDYY VVREPGQSPI FWYAPESLSD NIFSRQSDVW SFGVVLYELF
Predicted Reactivity Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, Dog : 90 %, Chicken : 70 %
Characteristics This is a rabbit polyclonal antibody against JAK3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human JAK3

Target Details JAK3

Product Details anti-JAK3 Antibody Application Details Handling References for anti-JAK3 Antibody (ABIN2785645) Images back to top
Antigen
Alternative Name JAK3 (JAK3 Antibody Abstract)
Background JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases, which is involved in cytokine receptor-mediated intracellular signal transduction. JAK3 is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in JAK3 are associated with autosomal SCID (severe combined immunodeficiency disease).The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.
Molecular Weight 125 kDa
Gene ID 3718
NCBI Accession NP_000206, NM_000215
UniProt P52333
Research Area Signaling, Cytokines, Receptors, Kinases/Phosphatases
Pathways JAK-STAT Signaling, RTK Signaling

Application Details

Product Details anti-JAK3 Antibody Target Details JAK3 Handling References for anti-JAK3 Antibody (ABIN2785645) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1124 AA

Restrictions For Research Use only

Handling

Product Details anti-JAK3 Antibody Target Details JAK3 Application Details References for anti-JAK3 Antibody (ABIN2785645) Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-JAK3 Antibody (ABIN2785645)

Product Details anti-JAK3 Antibody Target Details JAK3 Application Details Handling Images back to top
Background publications

Cheng, Ross, Frost, Kirken: "Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2271-82, 2008

Images

Product Details anti-JAK3 Antibody Target Details JAK3 Application Details Handling References for anti-JAK3 Antibody (ABIN2785645) back to top
Supplier Images
Western Blotting (WB) image for anti-JAK3 antibody (Tyrosine-Protein Kinase JAK3) (Middle Region) (ABIN2785645) WB Suggested Anti-JAK3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...