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Browse our JAK3 (JAK3) ELISA Kits

Full name:
Tyrosine-Protein Kinase JAK3 ELISA Kits (JAK3)
On www.antibodies-online.com are 20 Tyrosine-Protein Kinase JAK3 (JAK3) ELISA Kits from 10 different suppliers available. Additionally we are shipping JAK3 Antibodies (85) and JAK3 Proteins (12) and many more products for this protein. A total of 123 JAK3 products are currently listed.
Synonyms:
fae, JAK, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK, RATJAK3, wil
list all ELISA KIts Gene Name GeneID UniProt
JAK3 3718 P52333
JAK3 16453 Q62137
JAK3 25326  

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More ELISA Kits for JAK3 Interaction Partners

Human Tyrosine-Protein Kinase JAK3 (JAK3) interaction partners

  1. Foxp3 (show FOXP3 ELISA Kits) has a rapid turn over in Treg partly controlled at the transcriptional level by the JAK/STAT (show STAT1 ELISA Kits) pathway

  2. Results confirm that JAK3 is mutated in T-PLL and underscore the potential therapeutical relevance of epigenetic regulator.

  3. Data provide the first evidence that de-regulated Jak3/STAT3 (show STAT3 ELISA Kits)/STAT5 (show STAT5A ELISA Kits) signalling in CTCL (show TSPYL2 ELISA Kits) cells represses the expression of the gene encoding miR (show MLXIP ELISA Kits)-22, a novel tumor suppressor miRNA.

  4. Study describes three patients with a novel deep intronic mis (show AMH ELISA Kits)-splicing mutation in JAK3 as a cause of T-B+NK- severe combined immunodeficiency (show PRKDC ELISA Kits).

  5. Jak3 has a role in promoting mucosal tolerance through suppressed expression and limiting activation of TLRs thereby preventing intestinal and systemic chronic low-grade inflammation and associated obesity and MetS

  6. that JAK3 may contribute to the pathogenesis of pediatric ALL and serve as an important therapeutic target which can be leveraged to improve outcomes for pediatric patients with ALL.

  7. These results do not confirm association between JAK3 polymorphisms and cardiovascular disease in rheumatoid arthritis.

  8. Activating Janus kinase 3 mutation is associated with mycosis fungoides.

  9. The study reports the first patient with relapsed pediatric Early T-cell precursor acute lymphoblastic leukemia to exhibit a homozygous JAK3 activating mutation, V674A, caused by acquired uniparental disomy.

  10. JAK inhibitor ruxolitinib (that inhibits mainly the JAK3/STAT5 (show STAT5A ELISA Kits) pathway) affects key characteristics of human NK cells, such as cytokine-induced expansion and killing via an impaired cytokine-mediated NK cell activation

Mouse (Murine) Tyrosine-Protein Kinase JAK3 (JAK3) interaction partners

  1. Foxp3 (show FOXP3 ELISA Kits) has a rapid turn over in Treg partly controlled at the transcriptional level by the JAK/STAT (show STAT1 ELISA Kits) pathway

  2. JAK3 contributes to the regulation of membrane Kv1.5 (show KCNA5 ELISA Kits) protein abundance and activity, an effect sensitive to ouabain and thus possibly involving Na(+)/K(+) ATPase (show ATP1A1 ELISA Kits) activity.

  3. JAK3 deficiency is followed by down-regulation of cytosolic Ca(2 (show CA2 ELISA Kits)+) release, receptor and store operated Ca(2 (show CA2 ELISA Kits)+) entry and Na(+)/Ca(2 (show CA2 ELISA Kits)+) exchanger activity in dendritic cells.

  4. Jak3 has a role in promoting mucosal tolerance through suppressed expression and limiting activation of TLRs thereby preventing intestinal and systemic chronic low-grade inflammation and associated obesity and MetS (show MARS ELISA Kits)

  5. Our results demonstrate that JAK3/STAT6 (show STAT6 ELISA Kits) has an important role in bone marrow-derived fibroblast activation, extracellular matrix production, and interstitial fibrosis development.

  6. results showed that different JAK3 mutations induce constitutive activation through distinct mechanisms, pointing to specific therapeutic perspectives

  7. JAK3 down-regulates Na(+)/K(+)-ATPase (show ATP1A1 ELISA Kits) activity, an effect involving gene expression and profoundly curtailing ATP consumption.

  8. In conclusion, JAK3 deficiency leads to increased formation of calcitriol, which contributes to or even accounts for increased release of FGF23 (show FGF23 ELISA Kits) and enhanced intestinal phosphate absorption.

  9. JAK1 (show JAK1 ELISA Kits) and JAK3 mutants cooperate in T-cell transformation

  10. Jak3 pseudokinase mutants require JAK1 (show JAK1 ELISA Kits) for their transforming potential causing T-cell acute lymphoblastic leukemia in a mouse model.

Pig (Porcine) Tyrosine-Protein Kinase JAK3 (JAK3) interaction partners

  1. Data show that IL-4 (show IL4 ELISA Kits) induces upregulation of the junction protein claudin-5 (show CLDN5 ELISA Kits) in endothelial cells (ECs) through activation of Jak/STAT6 (show STAT6 ELISA Kits) and phosphorylation and translocation of FoxO1 (show FOXO1 ELISA Kits) from the nucleus to the cytoplasm.

JAK3 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Alternative names and synonyms associated with JAK3

  • Janus kinase 3 (JAK3) Elisa Kit
  • Janus kinase 3 (Jak3) Elisa Kit
  • fae Elisa Kit
  • JAK Elisa Kit
  • JAK-3 Elisa Kit
  • JAK3_HUMAN Elisa Kit
  • JAKL Elisa Kit
  • L-JAK Elisa Kit
  • LJAK Elisa Kit
  • RATJAK3 Elisa Kit
  • wil Elisa Kit

Protein level used designations for JAK3

Janus kinase 3 (a protein tyrosine kinase, leukocyte) , leukocyte Janus kinase , tyrosine-protein kinase JAK3 , JAK-3 , Janus kinase 3 protein-tyrosine kinase , Janus kinase 3, protein-tyrosine kinase , Janus tyrosine kinase

GENE ID SPECIES
100147451 Equus caballus
3718 Homo sapiens
16453 Mus musculus
25326 Rattus norvegicus
395845 Gallus gallus
610004 Canis lupus familiaris
100518649 Sus scrofa
538276 Bos taurus
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