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|Antigen||Leptin (LEP) Antibodies|
|Conjugate||This Leptin antibody is un-conjugated Alternatives|
Blocking Antibody (Inhibition), ELISA, Western Blotting (WB)
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Product Details anti-Leptin AntibodyTarget Details Leptin Application Details Handling Images
|Immunogen||Leptin antibody was raised in mouse using highly pure recombinant human leptin as the immunogen.|
Target Details LeptinProduct Details anti-Leptin Antibody Application Details Handling Images back to top
|Alternative Name||Leptin (LEP Antibody Abstract)|
|Background||Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Synonyms: Monoclonal Leptin antibody, Anti-Leptin antibody, Obesity antibody, OB antibody.|
|Molecular Weight||16.2 kDa (predicted detection band MW)|
|Research Area||Cardiovascular, Atherosclerosis, Hormones|
|Pathways||JAK-STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process|
Application DetailsProduct Details anti-Leptin Antibody Target Details Leptin Handling Images back to top
ELISA: 2-4 µg/mL, WB: 0.2-0.4 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Leptin Antibody Target Details Leptin Application Details Images back to top
|Buffer||Lyophilized from PBS.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.|