Browse our Leptin (LEP) ELISA Kits

Full name:
Leptin ELISA Kits (LEP)
On www.antibodies-online.com are 192 Leptin (LEP) ELISA Kits from 27 different suppliers available. Additionally we are shipping Leptin Antibodies (607) and Leptin Proteins (199) and many more products for this protein. A total of 1035 Leptin products are currently listed.
Synonyms:
LEPD, OB, obese, OBS

Top referenced Leptin ELISA Kits

  1. Rat (Rattus) Leptin ELISA Kit for Sandwich ELISA - ABIN625206 : Zhang, Wang, Long, Wang, Li, Gao, Tian: Alteration of sweet taste in high-fat diet induced obese rats after 4 weeks treatment with exenatide. in Peptides 2013 (PubMed)
    Show all 10 references for 625206

  2. Pig (Porcine) Leptin ELISA Kit for Sandwich ELISA - ABIN415853 : Walsh, Sweeney, Bahar, ODoherty: Multi-functional roles of chitosan as a potential protective agent against obesity. in PLoS ONE 2013 (PubMed)
    Show all 8 references for 415853

  3. Cow (Bovine) Leptin ELISA Kit for Competition ELISA - ABIN364601 : Osorio, Trevisi, Ballou, Bertoni, Drackley, Loor: Effect of the level of maternal energy intake prepartum on immunometabolic markers, polymorphonuclear leukocyte function, and neutrophil gene network expression in neonatal Holstein heifer calves. in Journal of dairy science 2013 (PubMed)
    Show all 5 references for 364601

  4. Human Leptin ELISA Kit for Sandwich ELISA - ABIN365165 : Tao, Zhang, Huang, Zhu, Zhang, Luo: The peritoneal leptin, MCP-1 and TNF-? in the pathogenesis of endometriosis-associated infertility. in American journal of reproductive immunology (New York, N.Y. : 1989) 2011 (PubMed)
    Show all 4 references for 365165

  5. Rabbit Leptin ELISA Kit for Sandwich ELISA - ABIN416007 : Vignozzi, Morelli, Sarchielli, Comeglio, Filippi, Cellai, Maneschi, Serni, Gacci, Carini, Piccinni, Saad, Adorini, Vannelli, Maggi: Testosterone protects from metabolic syndrome-associated prostate inflammation: an experimental study in rabbit. in The Journal of endocrinology 2011 (PubMed)
    Show all 3 references for 416007

  6. Salmon (Salmonidae) Leptin ELISA Kit for Competition ELISA - ABIN857634 : Kousoulaki, Østbye, Krasnov, Torgersen, Mørkøre, Sweetman: Metabolism, health and fillet nutritional quality in Atlantic salmon (Salmo salar) fed diets containing n-3-rich microalgae. in Journal of nutritional science 2015 (PubMed)
    Show all 3 references for 857634

  7. Chicken Leptin ELISA Kit for Sandwich ELISA - ABIN414108 : Hong, Wu, Ge, Zhou, Shen, Qiang, Zhang, Chen, Wang, Wang, Hong: Nanosized titanium dioxide resulted in the activation of TGF-β/Smads/p38MAPK pathway in renal inflammation and fibration of mice. in Journal of biomedical materials research. Part A 2016 (PubMed)

More ELISA Kits for Leptin Interaction Partners

Mouse (Murine) Leptin (LEP) interaction partners

  1. High fat diet attenuates leptin signaling throughout the brain, but some brain regions maintain their ability to sense leptin. Weight loss restores leptin sensing to some degree in most (but not all) brain regions, while other brain regions display hypersensitivity to leptin following weight loss

  2. CNS-specific Tak1 (show NR2C2 ELISA Kits) deletion prevented ER-stress-induced hypothalamic leptin resistance and hyperphagic obesity under a high-fat diet (HFD). Thus, TAK1 (show NR2C2 ELISA Kits) is a crucial regulator of ER stress in vivo, which could be a target for alleviation of ER stress and its associated disease conditions.

  3. These data further implicate IL-6 (show IL6 ELISA Kits) in fatty liver disease modulation in the context of DIO, and indicate that continuous stimulation with IL-6 (show IL6 ELISA Kits) attenuates the IL-6 (show IL6 ELISA Kits)-receptor response, which is associated with high serum levels of leptin.

  4. these data unmasked a role for mitochondrial fission in leptin sensitivity and glucose sensing of POMC (show POMC ELISA Kits) neurons.

  5. Obesity and leptin deficiency substantially decreased morphine metabolism and clearance.

  6. These findings suggest that by impairing the testicular LEP-JAK (show JAK3 ELISA Kits)-STAT (show STAT1 ELISA Kits) pathway, early-stage obesity inhibits the biosynthesis of testosterone and sexual development and reduces male reproductive potential. Long-term moderate and high-volume exercise can effectively reduce body fat and improve obesity-induced abnormalities in testicular leptin signal transduction, whereas only moderate-volume exercise can reverse the negativ

  7. genetic and pharmacological ablation of adult NG2 (show Vcan ELISA Kits)-glia (also known as oligodendrocyte precursors), but not microglia, leads to primary leptin resistance and obesity in mice.

  8. a novel mechanism of leptin-induced fatty acid oxidation in muscle tissue; namely, this process is dependent on the activation of AMPK (show PRKAA1 ELISA Kits) to induce the translocation of FAT/CD36 (show CD36 ELISA Kits) to the plasma membrane, thereby stimulating fatty acid uptake.

  9. Results demonstrate that in white adipose tissue, leptin expression and secretion is promoted by Epac1 (show RAPGEF3 ELISA Kits), hence regulating energy balance and glucose homeostasis.

  10. may regulate growth hormone (show GH1 ELISA Kits) expression in somatotropes through the stimulation of POU1F1 (show POU1F1 ELISA Kits)

Human Leptin (LEP) interaction partners

  1. Leptin, at concentrations with minimal or no activating effects on astrocytoma cells, enhanced growth and migration promoted by low doses of sPLA2-IIA (show PLA2G2A ELISA Kits). sPLA2-IIA (show PLA2G2A ELISA Kits) alone induced a transient phosphorylation pattern in the Src (show SRC ELISA Kits)/ERK (show EPHB2 ELISA Kits)/Akt (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits)/p70S6K (show RPS6KB1 ELISA Kits)/rS6 pathway through EGFR (show EGFR ELISA Kits) transactivation

  2. a novel mechanism by which compromised HDLECs maintain their homeostasis during inflammation mediated by leptin and IL-6 (show IL6 ELISA Kits)

  3. In this study of a predominantly minority population, no association between premorbid leptin levels and cancer incidence was demonstrated

  4. Centenarians had significant higher serum levels of leptin compared with controls (p<0.001), whereas no significant differences were observed for adiponectin (show ADIPOQ ELISA Kits).

  5. Studies suggest that metformin treatment was not associated with a decrease in blood leptin levels, or increases in blood ghrelin (show GHRL ELISA Kits) levels in patients with type 2 diabetes mellitus (T2DM).

  6. higher prediagnostic levels of plasma leptin were associated with an elevated risk of pancreatic cancer among men, but not among women

  7. Leptin levels are not significantly associated with incident atrial fibrillation in women.

  8. Results found an association between DNA methylation (show HELLS ELISA Kits) in each CpG site of the gene LEP, measured in saliva (show RAG1AP1 ELISA Kits), and obesity-related measures in 431 children aged 10- 15 years old. This association differed by sex and obesity status, with a much stronger association in obese boys.

  9. Data suggest caloric restriction modifies response of ovarian granulosa cells to leptin on cell proliferation/apoptosis, MAP kinase (show MAPK1 ELISA Kits) signaling, and release of hormones (estradiol and IGFI (show IGF1 ELISA Kits)). The caloric restriction studies were conducted in rabbits; then, isolated rabbit granulosa cells were exposed to recombinant human leptin. (IGF1 (show IGF1 ELISA Kits) = insulin-like growth factor I (show IGF1 ELISA Kits))

  10. Data suggest that modest weight loss in overweight adults due to caloric restriction and exercise decreases serum leptin (LEP) and high molecular weight adiponectin (ADPN), and increases serum pentraxin-3 (PTX3 (show PTX3 ELISA Kits)) in a manner that correlates with increased insulin (show INS ELISA Kits) sensitivity.

Pig (Porcine) Leptin (LEP) interaction partners

  1. The lack of effect of heat stress on the expression of leptin suggests that this peptide may not be involved in the reduction of feed intake of HS acclimated pigs.

  2. A high variability of the LEP was detected in the different analysed populations providing new data for the existence of two domestication centres in Asia.

  3. The presence of leptin and ObR (show LEPR ELISA Kits)-b varies across parities and is more intense in the uterus, ovaries and hypothalamus of females that were cycling before culling than in those having cystic ovaries.

  4. Studied 3'UTR (show UTS2R ELISA Kits) leptin polymorphism regulatory sequences' affect on gene expression and their association with production traits.

  5. These results suggest that LEPR, MC4R, PIK3C3 and VRTN are useful markers for accurately predicting breeding values in Duroc pigs.

  6. Data showing changes in expression patterns of LEP/LEPR (show LEPR ELISA Kits) in endometrium/chorioallantoic membrane during placentation/fetal development suggest role for LEP/LEPR (show LEPR ELISA Kits) complex at early stages of pregnancy, possibly affecting the attachment process.

  7. Another funning discovery is ob-Rb (show LEPR ELISA Kits) mRNA in porcine endometrium was mainly negative-regulated by leptin

  8. Characterization of a distinctive pattern of periovulatory leptin secretion and its relationship with ovulation rate and luteal function in swine with obesity/leptin resistance

  9. Leptin and leptin receptor (show LEPR ELISA Kits) are expressed in porcine luteal cells, and there is a modulatory effect of LH, estradiol (E) and progesterone (P) on leptin mRNA expression as well as E and P on leptin secretion by those cells obtained in early pregnancy.

  10. The present study aimed to determine the effects of breed and sex on growth patterns and metabolic features of advanced-pregnancy foetuses from lean and obese/leptin resistant swine.

Cow (Bovine) Leptin (LEP) interaction partners

  1. Consistent with this, leptin enhanced GnRH (show GNRH1 ELISA Kits)-induced secretion of LH measured by ELISA. We suggest that leptin enhances membrane expression of voltage-gated Na(+) and Ca(2 (show CA2 ELISA Kits)+) channels, which results in a modulation of the action potential properties and an increase in hormone release from gonadotropes.

  2. The effects of a single nucleotide polymorphism of leptin on weight gain and body composition are reported.

  3. A leptin SNP (LEPg.978) was significantly associated with a weight at one year.

  4. The results of this study suggest that leptin physiology could be a candidate for mechanisms that contribute to feed intake and feed efficiency variation in beef cattle.

  5. Leptin concentrations could be a useful physiological marker for growth and feed efficiency of finishing beef cattle.

  6. Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin-NPY (show NPY ELISA Kits) and insulin (show INS ELISA Kits) signaling pathways.

  7. Leptin R25C genotype impacted most traits associated with fatness.

  8. The absence of A80V polymorphism (C --> T at position 95691973 bp of leptin gene) has been established in the genotypes of Ayrshire cattle as compared to Holstein cattle.

  9. Data indicate that increased body weight gain during juvenile development accelerates sexual maturation in heifers, coincident with reciprocal changes in circulating concentrations of leptin and hypothalamic neuropeptide Y (NPY (show NPY ELISA Kits)) release.

  10. SNP LEP significantly affected milk, protein and fat yield (P<0.05), and age at first calving (P<0.01) in analyzed population of cows. SNP LEPR (show LEPR ELISA Kits)/T945M affected significantly calving interval (P<0.01) only

Goat Leptin (LEP) interaction partners

  1. polymorphisms of the LEP gene might be important genetic factors influencing growth traits, and these genetic markers may be useful for future marker-assisted selection programs in goat breeding and production

Rabbit Leptin (LEP) interaction partners

  1. study suggests that increased CSF (show CSF2 ELISA Kits) leptin, likely from blood-brain barrier breakdown, combined with elevated serum GH and IGF-1 (show IGF1 ELISA Kits) after traumatic brain injury, leads to accelerated fracture healing

  2. We conclude that offspring from mothers consuming a high fat diet exhibit an adverse cardiovascular profile in adulthood because of altered central hypothalamic sensitivity to leptin and ghrelin (show GHRL ELISA Kits).

  3. Niacin Reduces serum level and adipose mRNA expression of leptin and up-regulates PPARgamma (show PPARG ELISA Kits) and CD36 (show CD36 ELISA Kits) mRNA expression in hypercholesterolemic rabbits.

Horse (Equine) Leptin (LEP) interaction partners

  1. Positive correlations were found between leptin and total lipids, triglycerides, VLDLs, Total-Chol, and LDLs.

  2. Leptin metabolism in obese ponies following a return to free feeding after a period of food deprivation is reported.

  3. Plasma levels of leptin (as well as glucose, insulin (show INS ELISA Kits), and growth hormone (show GH1 ELISA Kits)) are highly correlated with the duration of winter anovulatory phase.

  4. GHRL (show GHRL ELISA Kits), LEP, ADIP (show SSX2IP ELISA Kits), INS (show INS ELISA Kits) and CORT (show CORT ELISA Kits) concentrations were measured using radioimmunoassay

  5. positive correlation between leptin and estradiol led us to suggest that leptin hormone plays an important role in ovulation of the first postpartum estrus in mares

Rhesus Monkey Leptin (LEP) interaction partners

  1. The effects of exogenous human kisspeptin-10 (KP10) were studied on three important adipokines, namely, adiponectin (show ADIPOQ ELISA Kits), leptin, and resistin (show RETN ELISA Kits) in a set of four chair-restraint habituated intact adult male rhesus monkeys.

  2. results do not support a role for reduced leptin secretion in anovulation induced by dietary restriction

Leptin (LEP) Antigen Profile

Antigen Summary

This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

Alternative names and synonyms associated with Leptin (LEP)

  • leptin (Lep) Elisa Kit
  • leptin (LEP) Elisa Kit
  • leptin (lep) Elisa Kit
  • LEPD Elisa Kit
  • OB Elisa Kit
  • obese Elisa Kit
  • OBS Elisa Kit

Protein level used designations for Leptin (LEP) ELISA Kits

obesity factor , leptin (murine obesity homolog) , leptin (obesity homolog, mouse) , obese protein , obese, mouse, homolog of , obese

GENE ID SPECIES
16846 Mus musculus
3952 Homo sapiens
25608 Rattus norvegicus
443534 Ovis aries
396832 Sus scrofa
280836 Bos taurus
100860794 Capra hircus
100008747 Oryctolagus cuniculus
373955 Gallus gallus
403616 Canis lupus familiaris
100034042 Equus caballus
493838 Felis catus
449638 Pan troglodytes
100716751 Cavia porcellus
698728 Macaca mulatta
548631 Takifugu rubripes
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