anti-Human Leptin Receptor antibody for Enzyme Immunoassay

Recommended Leptin Receptor Antibody (supplied by: Log in to see )

Antigen
Leptin Receptor (LEPR) Antibodies
  • obr
  • cd295
  • ob-rb
  • CD295
  • LEP-R
  • LEPRD
  • OB-R
  • OBR
  • ObRb
  • LEPROT
  • Leprb
  • Modb1
  • OB-RGRP
  • Obr
  • db
  • diabetes
  • obese-like
  • obl
  • Ob-R
  • Ob-RM
  • Fa
  • LEPR
  • Obrgrp
  • VPS55
  • leptin receptor
  • leptin receptor overlapping transcript
  • Leptin receptor-like
  • leptin receptor-like
  • lepr
  • LEPR
  • Lepr
  • Leprot
  • LOC100351924
  • LOC100069504
Epitope
Soluble
25
24
18
16
15
15
15
6
5
5
5
5
5
5
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
236
98
63
15
6
2
2
1
1
1
1
1
Host
Mouse
149
80
29
16
2
1
Clonality
Monoclonal
Conjugate
This Leptin Receptor antibody is un-conjugated
13
10
10
8
8
8
7
6
6
6
5
5
5
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
169
105
76
54
50
40
6
5
4
3
3
2
2
2
Supplier
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Catalog No. ABIN1106239
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN114694 EIA IHC (fro) WB Mouse IgG1 N-Term, C-Term, Extracellular Domain Log in to see LPR-01 1
1 ABIN114692 EIA IHC (fro) WB Mouse IgG1 Extracellular Domain Log in to see LPR-02 1
1 ABIN614904 EIA IHC (p) WB Goat Internal Region Log in to see Polyclonal
1 ABIN303460 EIA IHC (p) Rabbit AA 37-52 Log in to see Polyclonal
1 ABIN5553209 EIA WB Goat Internal Region Log in to see Polyclonal

General

Antigen Leptin Receptor (LEPR) Antibodies
Epitope Soluble
(25), (24), (18), (16), (15), (15), (15), (6), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(236), (98), (63), (15), (6), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(149), (80), (29), (16), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Leptin Receptor antibody is un-conjugated
(13), (10), (10), (8), (8), (8), (7), (6), (6), (6), (5), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(169), (105), (76), (54), (50), (40), (6), (5), (4), (3), (3), (2), (2), (2)
Pubmed 1 reference available
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Product Details anti-Leptin Receptor Antibody

Target Details Leptin Receptor Application Details Handling References for anti-Leptin Receptor antibody (ABIN1106239) Images
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein G
Clone 2F1
Isotype IgG1

Target Details Leptin Receptor

Product Details anti-Leptin Receptor Antibody Application Details Handling References for anti-Leptin Receptor antibody (ABIN1106239) Images back to top
Antigen
Alternative Name CD295 / Leptin Receptor (LEPR Antibody Abstract)
Background Leptin is a cytokine that is primarily expressed by adipose tissue. Leptin controls food intake by its interaction with the leptin receptor in the brain. Leptin action is mediated and controlled by the leptin receptor, a class I type cytokine receptor. sLR is generated by proteolytic cleavage of membrane-anchored receptors. This indicates that the leptin receptor might have other functions besides transduction. Binding of leptin with sLR increases the bioavailability of leptin in plasma, but also decreases the binding of leptin to membrane bound leptin receptors. For example, when comparing obese and lean individuals, plasma levels of sLR are significantly decreased whereas leptin levels are significantly increased.Synonyms: DB, HuB219, LEP-R, LEPR, OB receptor, OB-R, OBR
Gene ID 9606
UniProt P48357
Research Area Hormones, Receptors
Pathways JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour

Application Details

Product Details anti-Leptin Receptor Antibody Target Details Leptin Receptor Handling References for anti-Leptin Receptor antibody (ABIN1106239) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Leptin Receptor Antibody Target Details Leptin Receptor Application Details References for anti-Leptin Receptor antibody (ABIN1106239) Images back to top
Concentration 0.1 mg/mL
Buffer PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2 - 8 °C.

References for anti-Leptin Receptor antibody (ABIN1106239)

Product Details anti-Leptin Receptor Antibody Target Details Leptin Receptor Application Details Handling Images back to top
Background publications

van Dielen, van t Veer, Buurman, Greve: "Leptin and soluble leptin receptor levels in obese and weight-losing individuals." in: The Journal of clinical endocrinology and metabolism, Vol. 87, Issue 4, pp. 1708-16, 2002