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|Antigen||Leukemia Inhibitory Factor (LIF) Antibodies|
|Epitope||AA 79-109 Alternatives|
|Conjugate||This LIF antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|1 reference available|
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Product Details anti-LIF AntibodyTarget Details LIF Application Details Handling References for anti-LIF antibody (ABIN453168) Images
|Specificity||This antibody reactcs to Leukemia inhibitory factor|
|Purification||Protein A column, followed by peptide affinity purification|
|Immunogen||KLH conjugated synthetic peptide between 79~109 amino acids from the Center region of Human LIF|
Target Details LIFProduct Details anti-LIF Antibody Application Details Handling References for anti-LIF antibody (ABIN453168) Images back to top
|Alternative Name||Leukemia Inhibitory Factor (LIF Antibody Abstract)|
|Background||LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.Synonyms: D factor, Differentiation-stimulating factor, Emfilermin, HILDA, LIF, MLPLI, Melanoma-derived LPL inhibitor|
|Pathways||JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding|
Application DetailsProduct Details anti-LIF Antibody Target Details LIF Handling References for anti-LIF antibody (ABIN453168) Images back to top
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-LIF Antibody Target Details LIF Application Details References for anti-LIF antibody (ABIN453168) Images back to top
|Buffer||PBS with 0.09 % (W/V) Sodium Azide as preservative|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-LIF antibody (ABIN453168)Product Details anti-LIF Antibody Target Details LIF Application Details Handling Images back to top
Novotný, Krízan, Síma, Síma, Uher, Zech, Hütelová, Baborová, Ulcová-Gallová, Subrt, Ulmanová, Houdek, Rokyta, Babuska, Králícková: "Leukaemia inhibitory factor (LIF) gene mutations in women diagnosed with unexplained infertility and endometriosis have a negative impact on the IVF outcome. A pilot study." in: Folia biologica, Vol. 55, Issue 3, pp. 92-7, 2009
ImagesProduct Details anti-LIF Antibody Target Details LIF Application Details Handling References for anti-LIF antibody (ABIN453168) back to top