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LIG4 Proteins

(Ligase IV, DNA, ATP-Dependent (LIG4))

The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].

recommended

LIG4 Protein (AA 802-911) (GST tag) (ABIN1309405)

LIG4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

LIG4 Protein (AA 1-911) (Strep Tag) (ABIN3092165)

Crystallography grade LIG4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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recommended

LIG4 Protein (AA 1-911) (Strep Tag) (ABIN3136262)

Crystallography grade LIG4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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LIG4 Proteins by Grade

Find LIG4 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

LIG4 Proteins by Origin

Find LIG4 Proteins for a variety of species such as anti-Human LIG4, anti-Mouse LIG4. The species listed below are among those available. Click on a link to go to the corresponding products.

LIG4 Proteins by Source

Here you will find LIG4 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

LIG4 Proteins by Protein Type

Here you can find LIG4 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

LIG4 Proteins by Application

Find LIG4 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular LIG4 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

LIG4 Protein (AA 802-911) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1309405

Quantity 10 μg

Datasheet Datasheet

LIG4 Protein (AA 1-911) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3092165

Quantity 1 mg

Datasheet Datasheet

LIG4 Protein (AA 1-911) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3136262

Quantity 1 mg

Datasheet Datasheet

Aliases for LIG4 Proteins

ligase IV, DNA, ATP-dependent (lig4) Proteins
DNA ligase 4 (LIG4) Proteins
DNA ligase 4 (LOC100212302) Proteins
DNA ligase 4 (CpipJ_CPIJ005161) Proteins
DNA ligase 4 (PTRG_09982) Proteins
DNA ligase 4 (MCYG_05151) Proteins
DNA ligase 4 (LOC657210) Proteins
ATP-dependent DNA ligase implicated in dsDNA break repair via nonhomologous end-joining (LIG4) Proteins
DNA ligase IV (ATLIG4) Proteins
ligase IV, DNA, ATP-dependent L homeolog (lig4.L) Proteins
ligase IV, DNA, ATP-dependent (Lig4) Proteins
DNA ligase 4 (Lig4) Proteins
5830471N16Rik Proteins
DNA LIGASE IV Proteins
DNL4 Proteins
lig4 Proteins
LIG4 Proteins
lig4-A Proteins
tiny Proteins
zgc:165595 Proteins

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LIG4 Proteins by Grade

LIG4 Proteins by Origin

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Popular LIG4 Proteins

Aliases for LIG4 Proteins

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