anti-Dog (Canine) Oncostatin M Receptor antibody for Western Blotting

Recommended Oncostatin M Receptor Antibody (supplied by: Log in to see )

Antigen
Oncostatin M Receptor (OSMR) Antibodies
  • OSMRB
  • PLCA1
  • oncostatin M receptor
  • OSMR
  • Osmr
Epitope
Middle Region
18
15
7
6
5
5
4
4
3
3
3
2
1
1
1
1
1
1
Reactivity
Dog (Canine), Guinea Pig, Horse (Equine), Human, Rabbit
78
29
5
3
1
1
1
1
Host
Rabbit
44
29
23
16
Clonality
Polyclonal
Conjugate
This Oncostatin M Receptor antibody is un-conjugated
9
5
5
4
4
4
4
4
4
4
3
1
1
1
Application
Western Blotting (WB)
59
52
30
12
7
6
6
3
2
1
1
1
1
1
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Catalog No. ABIN2782613
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2206945 ABIN2782612 WB Rabbit N-Term Log in to see Polyclonal 1
1 ABIN321106 WB Rabbit IgG AA 21-70 Log in to see Polyclonal
1 ABIN2626466 IHC (p) WB Rabbit IgG AA 612-661 Log in to see Polyclonal

General

Antigen Oncostatin M Receptor (OSMR) Antibodies
Epitope Middle Region
(18), (15), (7), (6), (5), (5), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Guinea Pig, Horse (Equine), Human, Rabbit
(78), (29), (5), (3), (1), (1), (1), (1)
Host Rabbit
(44), (29), (23), (16)
Clonality
Polyclonal
Conjugate This Oncostatin M Receptor antibody is un-conjugated
(9), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (1), (1), (1)
Application Western Blotting (WB)
(59), (52), (30), (12), (7), (6), (6), (3), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Oncostatin M Receptor Antibody

Target Details Oncostatin M Receptor Application Details Handling References for anti-Oncostatin M Receptor antibody (ABIN2782613) Images
Blocking Peptide Blocking peptide for this product available: ABIN981219
Sequence LLEKKTGYSQ ELAPSDNPHV LVDTLTSHSF TLSWKDYSTE SQPGFIQGYH
Predicted Reactivity Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 92%
Characteristics This is a rabbit polyclonal antibody against OSMR. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human OSMR

Target Details Oncostatin M Receptor

Product Details anti-Oncostatin M Receptor Antibody Application Details Handling References for anti-Oncostatin M Receptor antibody (ABIN2782613) Images back to top
Antigen
Alternative Name OSMR (OSMR Antibody Abstract)
Background Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC150626, MGC150627, MGC75127, OSMRB, PLCA1
Protein Interaction Partner: UBC, CUL5, GAPDH, IL6ST, OSM, JAK2, JAK1, ERBB2,
Protein Size: 979
Molecular Weight 110 kDa
Gene ID 9180
NCBI Accession NM_003999, NP_003990
UniProt Q99650
Research Area Chromatin and Nuclear Signaling, Innate Immunity, Cytokines
Pathways JAK-STAT Signaling, Growth Factor Binding

Application Details

Product Details anti-Oncostatin M Receptor Antibody Target Details Oncostatin M Receptor Handling References for anti-Oncostatin M Receptor antibody (ABIN2782613) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 979 AA

Restrictions For Research Use only

Handling

Product Details anti-Oncostatin M Receptor Antibody Target Details Oncostatin M Receptor Application Details References for anti-Oncostatin M Receptor antibody (ABIN2782613) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Oncostatin M Receptor antibody (ABIN2782613)

Product Details anti-Oncostatin M Receptor Antibody Target Details Oncostatin M Receptor Application Details Handling Images back to top
Background publications

Arita, South, Hans-Filho, Sakuma, Lai-Cheong, Clements, Odashiro, Odashiro, Hans-Neto, Hans, Holder, Bhogal, Hartshorne, Akiyama, Shimizu, McGrath: "Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis." in: American journal of human genetics, Vol. 82, Issue 1, pp. 73-80, 2008

Images

Product Details anti-Oncostatin M Receptor Antibody Target Details Oncostatin M Receptor Application Details Handling References for anti-Oncostatin M Receptor antibody (ABIN2782613) back to top
Supplier Images
Western Blotting (WB) image for anti-Oncostatin M Receptor (OSMR) (Middle Region) antibody (ABIN2782613) WB Suggested Anti-OSMR Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...