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anti-Mouse (Murine) Oncostatin M Receptor antibody for ELISA

Recommended Oncostatin M Receptor Antibody (supplied by: Log in to see )

Antigen
Oncostatin M Receptor (OSMR) Antibodies
  • OSMRB
  • PLCA1
Epitope
AA 1-738
6
6
5
5
5
4
3
2
2
2
2
1
1
1
1
1
Reactivity
Mouse (Murine)
55
6
5
2
Host
Rabbit
39
13
11
3
Clonality
Polyclonal
Conjugate
This Oncostatin M Receptor antibody is un-conjugated
8
5
3
3
1
1
Minimum Detection Limit
0.00975 ng/well
Application
ELISA
43
25
14
4
3
3
3
2
1
1
1
Supplier
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Catalog No. ABIN2001045
$ 163.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0012121415 ABIN2214614 ELISA Rabbit Log in to see Polyclonal

Similar anti-Oncostatin M Receptor Antibodies

Application / Reactivity Mouse (Murine)
ELISA 2 Antibodies
Flow Cytometry (FACS) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Western Blotting (WB) 1 Antibodies

General

Antigen Oncostatin M Receptor (OSMR) Antibodies
Epitope AA 1-738
(6), (6), (5), (5), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(55), (6), (5), (2)
Host Rabbit
(39), (13), (11), (3)
Clonality
Polyclonal
Conjugate This Oncostatin M Receptor antibody is un-conjugated
(8), (5), (3), (3), (1), (1)
Minimum Detection Limit 0.00975 ng/well
Application ELISA
(43), (25), (14), (4), (3), (3), (3), (2), (1), (1), (1)
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Product Details anti-Oncostatin M Receptor Antibody

Target Details Oncostatin M Receptor Application Details Handling Images
Specificity Mouse OSMR / IL-31RB
Characteristics Produced in rabbits immunized with purified, recombinant Mouse OSMR / IL-31RB (rM OSMR / IL-31RB, O70458-1, Met 1-Leu 738). Total IgG was purified by Protein A affinity chromatography.
Purification Affinity Purified
Sterility 0.2 μm filtered
Isotype IgG

Target Details Oncostatin M Receptor

Product Details anti-Oncostatin M Receptor Antibody Application Details Handling Images back to top
Antigen
Alternative Name OSMR (OSMR Antibody Abstract)
Background Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the type I cytokine receptor family. IL-31RB/OSMR heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in IL-31RB/OSMR have been associated with familial primary localized cutaneous amyloidosis. Defects in IL-31RB/OSMR are the cause of amyloidosis primary localized cutaneous type 1 (PLCA1), also known as familial lichen amyloidosis or familial cutaneous lichen amyloidosis. PLCA1 is a hereditary primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening (lichenification) that may be exacerbated by chronic scratching and rubbing. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins.
UniProt O70458-1
Research Area Chromatin and Nuclear Signaling, Innate Immunity, Cytokines
Pathways JAK-STAT Signaling

Application Details

Product Details anti-Oncostatin M Receptor Antibody Target Details Oncostatin M Receptor Handling Images back to top
Application Notes ELISA ELISA: 0.5-1 µg/mL This antibody can be used at 0.5-1 µg/mL with the appropriate secondary reagents to detect Mouse OSMR. The detection limit for Mouse OSMR is approximately 0.00975 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-Oncostatin M Receptor Antibody Target Details Oncostatin M Receptor Application Details Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months