anti-Dog (Canine) PIAS2 antibody for Immunohistochemistry

Recommended PIAS2 Antibody (supplied by: Log in to see )

Antigen
Protein Inhibitor of Activated STAT, 2 (PIAS2) Antibodies
  • MGC83751
  • piasx
  • wu:fi05f09
  • PIAS2
  • 6330408K17Rik
  • AI462206
  • ARIP3
  • AU018068
  • Dib
  • Miz1
  • PIASxalpha
  • PIASxb
  • PIASxbeta
  • SIZ2
  • DIP
  • MIZ
  • MIZ1
  • PIASX
  • PIASX-ALPHA
  • PIASX-BETA
  • ZMIZ4
  • protein inhibitor of activated STAT, 2
  • protein inhibitor of activated STAT 2
  • pias2
  • PIAS2
  • Pias2
Epitope
C-Term
28
18
17
5
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Rabbit
122
53
46
21
14
11
11
5
5
4
2
2
1
Host
Rabbit
82
34
7
2
Clonality
Polyclonal
Conjugate
This PIAS2 antibody is un-conjugated
4
4
4
4
4
4
Application
Immunohistochemistry (IHC), Western Blotting (WB)
99
69
48
14
14
4
3
2
1
1
Options
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Available images

Catalog No. ABIN2779873
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN216786 IHC WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN2564530 IHC ELISA Goat IgG Internal Region Log in to see Polyclonal

Similar anti-PIAS2 Antibodies

Application / Reactivity Human Dog (Canine) Mouse (Murine) Cow (Bovine) Horse (Equine) Rabbit
Western Blotting (WB) 97 Antibodies 16 Antibodies 47 Antibodies 14 Antibodies 11 Antibodies 11 Antibodies
RNA Interference (RNAi) 1 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies 4 Antibodies 6 Antibodies 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 47 Antibodies 16 Antibodies 3 Antibodies 1 Antibodies 2 Antibodies 1 Antibodies

General

Antigen Protein Inhibitor of Activated STAT, 2 (PIAS2) Antibodies
Epitope C-Term
(28), (18), (17), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Rabbit
(122), (53), (46), (21), (14), (11), (11), (5), (5), (4), (2), (2), (1)
Host Rabbit
(82), (34), (7), (2)
Clonality
Polyclonal
Conjugate This PIAS2 antibody is un-conjugated
(4), (4), (4), (4), (4), (4)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(99), (69), (48), (14), (14), (4), (3), (2), (1), (1)
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Product Details anti-PIAS2 Antibody

Target Details PIAS2 Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN981729
Sequence LSLIPVDPQY CPPMFLDSLT SPLTASSTSV TTTSPHESST HVSSSSSRSE
Predicted Reactivity Cow: 93%, Dog: 100%, Horse: 100%, Human: 93%, Mouse: 100%, Rabbit: 93%
Characteristics This is a rabbit polyclonal antibody against Pias2. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of mouse Pias2

Target Details PIAS2

Product Details anti-PIAS2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Pias2 (PIAS2 Antibody Abstract)
Background Pias2 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. It plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It seems to be mostly involved in gene silencing. It binds to sumoylated ELK1 and enhances its transcriptional activity by preventing recruitment of HDAC2 by ELK1, thus reversing SUMO-mediated repression of ELK1 transactivation activity.
Alias Symbols: 6330408K17Rik, AI462206, ARIP3, AU018068, Dib, Miz1, PIASxalpha, PIASxb, PIASxbeta, SIZ2
Protein Interaction Partner: Pparg, Egr2, Plagl2, Trim32, Trp53, DHX9, Nfkb1, Gtf2i, GTF2IRD1, HDAC3,
Protein Size: 490
Molecular Weight 54 kDa
Gene ID 17344
NCBI Accession NM_001164167
UniProt Q8C5D8
Research Area Proteolysis / Ubiquitin, Transcription Factors, Chromatin and Nuclear Signaling
Pathways JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling

Application Details

Product Details anti-PIAS2 Antibody Target Details PIAS2 Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 490 AA

Restrictions For Research Use only

Handling

Product Details anti-PIAS2 Antibody Target Details PIAS2 Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-PIAS2 Antibody Target Details PIAS2 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-PIAS2 antibody (Protein Inhibitor of Activated STAT, 2) (C-Term) (ABIN2779873) WB Suggested Anti-Pias2 Antibody Titration: 0.2-1 ug/ml
Positive Control...
Immunohistochemistry (IHC) image for anti-PIAS2 antibody (Protein Inhibitor of Activated STAT, 2) (C-Term) (ABIN2779873) anti-Protein Inhibitor of Activated STAT, 2 (PIAS2) (C-Term) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-PIAS2 antibody (Protein Inhibitor of Activated STAT, 2) (C-Term) (ABIN2779873) Mouse Pancreas