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Browse our Prolactin Proteins (PRL)

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Prolactin Proteins (PRL)
On are 146 Prolactin (PRL) Proteins from 20 different suppliers available. Additionally we are shipping Prolactin Antibodies (466) and Prolactin Kits (116) and many more products for this protein. A total of 746 Prolactin products are currently listed.
AV290867, prl, Prl1a1, PRLB, PRLSD1, Prol, prolactin, RATPRLSD1, RNPROL
list all proteins Gene Name GeneID UniProt
PRL 5617 P01236
Rat PRL PRL 24683 P01237
Mouse PRL PRL 19109  

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Prolactin Proteins (PRL) by Origin

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Top referenced Prolactin Proteins

  1. Human Prolactin Protein expressed in Escherichia coli (E. coli) - ABIN2666567 : Ben-Jonathan, LaPensee, LaPensee: What can we learn from rodents about prolactin in humans? in Endocrine reviews 2008 (PubMed)
    Show all 7 references for ABIN2666567

  2. Mouse (Murine) Prolactin Protein expressed in Baculovirus infected Insect Cells - ABIN2007718 : Tworoger, Hankinson: Prolactin and breast cancer risk. in Cancer letters 2006 (PubMed)

More Proteins for Prolactin Interaction Partners

Human Prolactin (PRL) interaction partners

  1. PAK1 (show PAK1 Proteins) nuclear translocation is ligand-dependent: only PRL but not E2 stimulated PAK1 (show PAK1 Proteins) nuclear translocation

  2. Mean serum prolactin level was higher in the patients with recurrent miscarriage than in healthy women.

  3. findings revealed that the -1149TT genotype was correlated with higher levels of prolactin in serum and prolactin gene expression in peripheral blood mononuclear cells in women with systemic lupus erythematosus; study suggests that the -1149TT genotype may be a risk factor for lupus

  4. Despite the fact that serum prolactin levels were found to be high during pregnancy, the contribution of macroprolactin was found to be insignificant. No relationship between thyroid autoimmunity and PRL, macroPRL or monoPRL % was found.

  5. PRL is ectopically activated in a subset of very aggressive lung tumors, associated with a rapid fatal outcome, in a cohort of 293 lung tumor patients and in an external independent series of patients; analysis of the PRL transcripts in lung tumors and cell lines revealed systematic truncations of their 5' regions, including the signal peptide-encoding portions.

  6. PRL-PRLR (show PRLR Proteins) can escalate the impact of breast cancer on bone metastasis and the presence of PRLR (show PRLR Proteins) in the tumor microenvironment of breast cancer bone metastasis has the potential to modulate the microenvironment to induce lytic osteoclast formation.

  7. Women with higher prolactin levels did not report significantly increased hostility.

  8. results suggest that up-regulation of IL-10 (show IL10 Proteins) by prolactin might be modulating the pro-inflammatory response against mycobacterial antigens through the MAPK (show MAPK1 Proteins) pathway

  9. there is a link between prolactin and mean platelet volume levels; in women with PCOS, elevated PRL levels may increase the risk of developing atherothrombotic events via the activation of platelets

  10. Our data extends prior research linking prolactin and invasive breast cancer to the outcome of in situ breast tumours and shows that higher circulating prolactin is associated with increased risk of in situ breast cancer.

Mouse (Murine) Prolactin (PRL) interaction partners

  1. Twenty-two separate mouse genes encode the placenta Prl-related hormones

  2. Prolactin transport into mouse brain is independent of prolactin receptor (show PRLR Proteins).

  3. Survivin (show BIRC5 Proteins) directly participates in PRL-mediated beta cell proliferation via Akt (show AKT1 Proteins), STAT5 (show STAT5A Proteins)-PIM (show PIM1 Proteins) and ERK (show EPHB2 Proteins) signalling pathways during pregnancy

  4. the mechanism by which kisspeptin is suppressed during lactation involves a number of factors, including chronically elevated levels of prolactin

  5. Over 24 hours, males displayed no oscillation in PRL level; virgin and lactating females showed large pulses. Peaks reached 30-40 ng/mL in lactating mice and rarely exceeded 10 ng/mL in virgin mice. Pulses in lactating mice were associated with suckling.

  6. Prolactin induces apoptosis of lactotropes

  7. N-terminal PRL fragment increases during the involution period, has a proapoptotic effect on mammary epithelial cells, and is mainly generated by secreted cathepsin D (show CTSD Proteins) in the extracellular space of mammary glands.

  8. PRL constrains tumor-promoting liver inflammation.

  9. Prolactin levels correlate with abnormal B cell maturation (show TNFRSF17 Proteins) in MRL and MRL/lpr (show FAS Proteins) mouse models of systemic lupus erythematosus-like disease.

  10. Results show that mammary prolactin decreased the latency of tumors in the absence of p53 (show TP53 Proteins), and increased the proportion of triple-negative claudin-low carcinomas.

Cow (Bovine) Prolactin (PRL) interaction partners

  1. The presence and localization of prolactin receptor (show PRLR Proteins) are consistent with expression data reported for other species, and the presence of PIP (show PIP Proteins) and prolactin in seminal fluid is consistent with data generated in humans.

  2. Functionally reciprocal mutations of the prolactin signaling pathway define hairy and slick cattle.

  3. The single nucleotide polymorphism rs42646708 of cattle XKR4 was significantly associated with serum prolactin concentrations and explained 2.45% of the phenotypic variation.

  4. Five mutations were identified in exonic region and eleven in associated intronic regions in PRL gene in 100 cattle from four Pakistani cattle breeds.

  5. this study identifies a biochemical mechanism for the regulation of SCFAs on bovine GH and PRL gene transcription in dairy cow anterior pituitary cells

  6. These data suggest that PRL protects brain endothelial cells against methamphetamine-induced toxicity

  7. Bovine prolactin improved the expression of human transferrin (show Tf Proteins) through such a possible mechanism that bovine prolactin activated STAT5a (show STAT5A Proteins) transcription expression.

  8. There was no significant difference between 1134 locus and milk performance traits of 5'-UTR of PRL gene

  9. Staphylococcus aureus infection inhibits nuclear factor kappa B activation mediated by prolactin in bovine mammary epithelial cells.

  10. Study of genetic variation in Yakutian cattle (Bos taurus L.) using the prolactin bPRL, growth hormone bGH, and transcription factor bPit-1 genes

Pig (Porcine) Prolactin (PRL) interaction partners

  1. Prolactin and, to a lesser extent progesterone, which increase in early pregnancy, enhance basal and glucose-stimulated insulin (show INS Proteins) secretion in part by increasing glucokinase (show GCK Proteins) activity and amplifying cAMP levels.

  2. iv infusion of prolactin primarily caused coronary, mesenteric, renal, and iliac vasoconstriction

  3. despite a lack of clear relationship between PRL/C499T polymorphism in 5' UTR of the PRL gene and plasma prolactin cioncentration, gene polymorphism impact on reproductiove performance cannot be excluded

Prolactin (PRL) Protein Profile

Protein Summary

This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein.

Alternative names and synonyms associated with Prolactin (PRL)

  • prolactin (PRL)
  • prolactin, gene 3 (prl.3)
  • prolactin (Prl)
  • prolactin (LOC100136792)
  • prolactin (LOC100136580)
  • prolactin-like (LOC101843376)
  • AV290867 protein
  • prl protein
  • Prl1a1 protein
  • PRLB protein
  • PRLSD1 protein
  • Prol protein
  • prolactin protein
  • RATPRLSD1 protein
  • RNPROL protein

Protein level used designations for Prolactin Proteins (PRL)

prolactin , prolactin, gene 3 , prolactin 2 , decidual prolactin , prolactin family 1, subfamily a, member 1 , preprolactin

100126745 Papio anubis
100310824 Xenopus laevis
5617 Homo sapiens
443317 Ovis aries
24683 Rattus norvegicus
19109 Mus musculus
280901 Bos taurus
488241 Canis lupus familiaris
751517 Felis catus
396453 Gallus gallus
100009394 Oryctolagus cuniculus
396965 Sus scrofa
100499538 Cavia porcellus
100034034 Equus caballus
707052 Macaca mulatta
100136792 Oncorhynchus mykiss
100136580 Salmo salar
100481524 Ailuropoda melanoleuca
100861193 Capra hircus
101843376 Mesocricetus auratus
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