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anti-Human Prolactin Receptor antibody for Immunofluorescence

Recommended Prolactin Receptor Antibody (supplied by: Log in to see )

Antigen
Prolactin Receptor (PRLR) Antibodies
  • AI987712
  • DKFZp469D061
  • hPRLrI
  • Pr-1
  • Pr-3
  • PRL-R
  • PRLR
  • prlr
  • Prlr-rs1
  • PRLRb
  • RATPRLR
  • tprlr
Epitope
AA 1-234
13
6
5
5
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
93
33
17
1
Host
Rabbit
55
45
7
4
Clonality
Monoclonal
Conjugate
This Prolactin Receptor antibody is un-conjugated
3
2
1
1
1
1
1
1
1
1
1
1
1
1
Minimum Detection Limit
0.00245 ng/well
Application
Flow Cytometry (FACS), Immunofluorescence (IF), ELISA
64
31
28
20
18
16
12
11
3
3
2
2
2
1
1
Supplier
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Supplier Product No.
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Available images

Catalog No. ABIN1996249
$ 273.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.3121241 ABIN152720 ICC FACS IHC (fro) IF IHC (p) IP IHC WB Mouse IgG1 Log in to see U5
0.0010962716 ABIN2342067 FACS IF IP IHC WB Mouse IgG1 kappa Log in to see PRLR742
0.0010962716 ABIN2342070 FACS IF IP IHC WB Mouse IgG1 kappa Log in to see B6-2-PRLR742
0.0010962716 ABIN2342075 FACS IF IP IHC ELISA WB Mouse IgG1 kappa Log in to see SPM213
0.0010962716 ABIN2342076 FACS IF IP IHC WB Mouse IgG1 kappa Log in to see B6-2
0.0010962716 ABIN3026655 FACS IF IHC Mouse IgG1, kappa Log in to see PRLR742
0.0010962716 ABIN2342057 FACS IF IP IHC ELISA WB Mouse IgG1 kappa Log in to see SPM213
0.0010962716 ABIN3025093 FACS IF IHC Mouse IgG1, kappa Log in to see B6-2
0.0010962716 ABIN3025096 FACS IF IHC Mouse IgG1 Log in to see B6-2-PRLR742
0.0010962716 ABIN3025099 FACS IF IHC Mouse IgG1, kappa Log in to see SPM213
0.0010962716 ABIN3025426 IF IHC Mouse IgG1, kappa Log in to see ERSV8-1
0.0010962716 ABIN3026657 FACS IF IHC Mouse IgG1, kappa Log in to see PRLR742
0.0010962716 ABIN3025095 FACS IF IHC Mouse IgG1, kappa Log in to see B6-2
0.0010962716 ABIN3025098 FACS IF IHC Mouse IgG1 Log in to see B6-2-PRLR742
0.0010962716 ABIN3025100 FACS IF IHC Mouse IgG1, kappa Log in to see SPM213
0.0010962716 ABIN3025428 IF IHC Mouse IgG1, kappa Log in to see ERSV8-1

Similar anti-Prolactin Receptor Antibodies

Application / Reactivity Human
Dot Blot (DB) 1 Antibodies
ELISA 21 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 18 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 17 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 28 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies
Immunoprecipitation (IP) 10 Antibodies
Neutralization (Neut) 1 Antibodies
Western Blotting (WB) 54 Antibodies

General

Antigen Prolactin Receptor (PRLR) Antibodies
Epitope AA 1-234
(13), (6), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(93), (33), (17), (1)
Host Rabbit
(55), (45), (7), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Prolactin Receptor antibody is un-conjugated
(3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Minimum Detection Limit 0.00245 ng/well
Application Flow Cytometry (FACS), Immunofluorescence (IF), ELISA
(64), (31), (28), (20), (18), (16), (12), (11), (3), (3), (2), (2), (2), (1), (1)
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Product Details anti-Prolactin Receptor Antibody

Target Details Prolactin Receptor Application Details Handling Images
Specificity Human PRLR / Prolactin Receptor
Characteristics This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human PRLR ( rh PRLR , NP_000940.1 , Met 1 - Asp 234 ).
Sterility 0.2 μm filtered
Immunogen Recombinant human PRLR protein
Clone 204
Isotype IgG

Target Details Prolactin Receptor

Product Details anti-Prolactin Receptor Antibody Application Details Handling Images back to top
Antigen
Alternative Name PRLR (PRLR Antibody Abstract)
Background Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the typeI cytokine receptor superfamily, and contains two fibronectin type-III domains. PRLR is widely expressed in breast, placenta, kidney, liver and pancreas, and mainly serves as the receptor for the pituitary hormone prolactin (PRL), a secreted hormone that affects reproduction and homeostasis in vertebrates. All class 1 ligands activate their respective receptors by clustering mechanisms. Ligand binding results in the transmembrane PRLR dimerization, followed by phosphorylation and activation of the molecules invloved in the signaling pathways, such as Jak-STAT, Ras/Raf/MAPK. It has been shown that specific binding to PRLR can stimulate the breast cancer cells to grow and certain antagonists which bind but do not dimerize PRLR can inhibit the growth of breast cancer cells. Several isoforms have been described, and the soluble form are unable to transduce prolactin signaling.
NCBI Accession NP_000940.1
Pathways JAK-STAT Signaling

Application Details

Product Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Handling Images back to top
Application Notes Direct ELISA - This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human PRLR. The detection limit for human PRLR is approximately 0.00245 ng/well Immunochemistry - ICC/IF: 10-25 μg/mL
Restrictions For Research Use only

Handling

Product Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Application Details Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months

Images

Product Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Application Details Handling back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Prolactin Receptor antibody (PRLR) (AA 1-234) (ABIN1996249) anti-Prolactin Receptor (PRLR) (AA 1-234) antibody
Immunofluorescence (IF) image for anti-Prolactin Receptor antibody (PRLR) (AA 1-234) (ABIN1996249) anti-Prolactin Receptor (PRLR) (AA 1-234) antibody (Image 2)