anti-Rat (Rattus) Prolactin Receptor antibody for ELISA

Recommended Prolactin Receptor Antibody (supplied by: Log in to see )

Antigen
Prolactin Receptor (PRLR) Antibodies
  • PRL-R
  • prlr
  • PRLR
  • tprlr
  • DKFZp469D061
  • hPRLrI
  • AI987712
  • Pr-1
  • Pr-3
  • Prlr-rs1
  • RATPRLR
  • PRLRb
  • prolactin receptor
  • prlr-a
  • prlr-b
  • PRLR
  • prlr
  • Prlr
  • PR
Epitope
AA 1-229
15
7
7
6
6
5
4
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Rat (Rattus)
204
66
36
17
17
16
15
15
13
2
2
2
2
1
Host
Rabbit
159
66
6
4
Clonality
Polyclonal
Conjugate
This Prolactin Receptor antibody is un-conjugated
7
7
7
7
6
6
6
6
6
6
6
6
6
5
4
4
2
1
1
1
1
1
1
1
1
1
1
Application
ELISA
175
129
107
105
92
88
80
79
51
13
4
2
2
2
2
1
1
1
1
1
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Catalog No. ABIN2001649
$ 163.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2476231 ELISA WB Sheep IgG AA 1-14 Log in to see Polyclonal 2
1 ABIN2577050 ELISA WB Biotin Rabbit IgG AA 20-229 Log in to see Polyclonal
1 ABIN2577051 ELISA WB FITC Rabbit IgG AA 20-229 Log in to see Polyclonal
1 ABIN2577053 IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2577049 ELISA WB Rabbit IgG AA 20-229 Log in to see Polyclonal
1 ABIN2214698 ELISA Rabbit IgG AA 1-229 Log in to see Polyclonal
1 ABIN1176618 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN5508167 ELISA Rabbit IgG AA 1-229 Log in to see 001
1 ABIN5508168 ELISA Rabbit IgG AA 1-229 Log in to see 113
1 ABIN2921694 ELISA IF/ICC IHC WB Rabbit AA 20-229 Log in to see Polyclonal
1 ABIN1099579 IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-Prolactin Receptor antibody for ELISA

Similar anti-Prolactin Receptor Antibodies

Application / Reactivity Rat (Rattus)
ELISA 12 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 15 Antibodies
Functional Studies (Func) 1 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 7 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 21 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 13 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 34 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Neutralization (Neut) 1 Antibodies
Western Blotting (WB) 49 Antibodies

General

Antigen Prolactin Receptor (PRLR) Antibodies
Epitope AA 1-229
(15), (7), (7), (6), (6), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Rat (Rattus)
(204), (66), (36), (17), (17), (16), (15), (15), (13), (2), (2), (2), (2), (1)
Host Rabbit
(159), (66), (6), (4)
Clonality
Polyclonal
Conjugate This Prolactin Receptor antibody is un-conjugated
(7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (4), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA
(175), (129), (107), (105), (92), (88), (80), (79), (51), (13), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Prolactin Receptor Antibody

Target Details Prolactin Receptor Application Details Handling ProductDetails: References for anti-Prolactin Receptor antibody (ABIN2001649) Images
Specificity Rat PRLR
Characteristics Produced in rabbits immunized with purified, recombinant Rat PRLR (rR PRLR, ABIN2009108 P05710-1, Met 1-Asp 229,. Total IgG was purified by Protein A affinity chromatography.
Purification purified by Protein A affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Rat PRLR protein (ABIN2009108)
Isotype IgG

Target Details Prolactin Receptor

Product Details anti-Prolactin Receptor Antibody Application Details Handling ProductDetails: References for anti-Prolactin Receptor antibody (ABIN2001649) Images back to top
Antigen
Alternative Name PRLR (PRLR Antibody Abstract)
Background Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type â..., cytokine receptor superfamily, and contains two fibronectin type-â...c domains. All class 1 ligands activate their respective receptors by clustering mechanisms. Ligand binding results in the transmembrane PRLR dimerization, followed by phosphorylation and activation of the molecules invloved in the signaling pathways, such as Jak-STAT, Ras/Raf/MAPK. The PRLR contains no intrinsic tyrosine kinase cytoplasmic domain but associates with a cytoplasmic tyrosine kinase, JAK2. PRLR mainly serves as the receptor for the pituitary hormone prolactin (PRL), a secreted hormone that affects reproduction and homeostasis in vertebrates. PRLR can be regulated by an interplay of two different mechanisms, PRL or ovarian steroid hormones independently or in combination in a tissue-specific manner. The role of the hormone prolactin (PRL) in the pathogenesis of breast cancer is mediated by its cognate receptor (PRLR). Ubiquitin-dependent degradation of the PRLR that negatively regulates PRL signaling is triggered by PRL-mediated phosphorylation of PRLR on Ser349 followed by the recruitment of the beta-transducin repeats-containing protein (beta- TrCP) ubiquitin-protein isopeptide ligase. which altered PRLR stability may directly influence the pathogenesis of breast cancer.
UniProt P05710-1
Pathways JAK-STAT Signaling, Response to Growth Hormone Stimulus

Application Details

Product Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Handling ProductDetails: References for anti-Prolactin Receptor antibody (ABIN2001649) Images back to top
Application Notes ELISA: 0.5-1 μg/mL
This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Rat PRLR. The detection limit for Rat PRLR is approximately 0.039 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Application Details ProductDetails: References for anti-Prolactin Receptor antibody (ABIN2001649) Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

ProductDetails: References for anti-Prolactin Receptor antibody (ABIN2001649)

Product Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Application Details Handling Images back to top
Background publications

Goffin, Binart, Clément-Lacroix, Bouchard, Bole-Feysot, Edery, Lucas, Touraine, Pezet, Maaskant, Pichard, Helloco, Baran, Favre, Bernichtein, Allamando, Ormandy, Kelly: "From the molecular biology of prolactin and its receptor to the lessons learned from knockout mice models." in: Genetic analysis : biomolecular engineering, Vol. 15, Issue 3-5, pp. 189-201, 2000