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anti-Rat (Rattus) Prolactin Receptor antibody for ELISA

Recommended Prolactin Receptor Antibody (supplied by: Log in to see )

Antigen
Prolactin Receptor (PRLR) Antibodies
  • AI987712
  • DKFZp469D061
  • hPRLrI
  • Pr-1
  • Pr-3
  • PRL-R
  • PRLR
  • prlr
  • Prlr-rs1
  • PRLRb
  • RATPRLR
  • tprlr
Epitope
AA 1-229
13
6
5
5
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Rat (Rattus)
201
60
31
15
14
14
14
14
14
Host
Rabbit
165
56
7
4
Clonality
Polyclonal
Conjugate
This Prolactin Receptor antibody is un-conjugated
7
7
7
7
6
6
6
6
6
6
6
6
6
6
5
4
4
2
1
1
1
1
1
1
1
1
Minimum Detection Limit
0.039 ng/well
Application
ELISA
178
123
117
103
98
91
82
59
34
11
2
2
2
1
1
Supplier
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Catalog No. ABIN2001649
$ 163.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0012117105 ABIN1176616 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 20-229 Log in to see Polyclonal
0.0012117105 ABIN2476231 ELISA WB Sheep IgG AA 1-14 Log in to see Polyclonal 2
0.0012117105 ABIN2577050 ELISA Biotin Rabbit IgG AA 20-229 Log in to see Polyclonal
0.0012117105 ABIN2577049 ELISA Rabbit IgG AA 20-229 Log in to see Polyclonal
0.0012117105 ABIN2577053 IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
0.0012117105 ABIN1176618 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
0.0012117105 ABIN1099579 IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
0.0012117105 ABIN2214698 ELISA Rabbit Log in to see Polyclonal

Top referenced anti-Prolactin Receptor antibody for ELISA

Similar anti-Prolactin Receptor Antibodies

Application / Reactivity Rat (Rattus)
ELISA 9 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 16 Antibodies
Functional Studies (Func) 1 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 31 Antibodies
Immunofluorescence (IF) 29 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 32 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 17 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 38 Antibodies
Immunoprecipitation (IP) 17 Antibodies
Neutralization (Neut) 1 Antibodies
Western Blotting (WB) 46 Antibodies

General

Antigen Prolactin Receptor (PRLR) Antibodies
Epitope AA 1-229
(13), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Rat (Rattus)
(201), (60), (31), (15), (14), (14), (14), (14), (14)
Host Rabbit
(165), (56), (7), (4)
Clonality
Polyclonal
Conjugate This Prolactin Receptor antibody is un-conjugated
(7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (4), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Minimum Detection Limit 0.039 ng/well
Application ELISA
(178), (123), (117), (103), (98), (91), (82), (59), (34), (11), (2), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-Prolactin Receptor Antibody

Target Details Prolactin Receptor Application Details Handling References for anti-Prolactin Receptor Antibody (ABIN2001649) Images
Specificity Rat PRLR
Characteristics Produced in rabbits immunized with purified, recombinant Rat PRLR (rR PRLR, P05710-1, Met 1-Asp 229). Total IgG was purified by Protein A affinity chromatography.
Purification Affinity Purified
Sterility 0.2 μm filtered
Isotype IgG

Target Details Prolactin Receptor

Product Details anti-Prolactin Receptor Antibody Application Details Handling References for anti-Prolactin Receptor Antibody (ABIN2001649) Images back to top
Antigen
Alternative Name PRLR (PRLR Antibody Abstract)
Background Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type â..., cytokine receptor superfamily, and contains two fibronectin type-â...c domains. All class 1 ligands activate their respective receptors by clustering mechanisms. Ligand binding results in the transmembrane PRLR dimerization, followed by phosphorylation and activation of the molecules invloved in the signaling pathways, such as Jak-STAT, Ras/Raf/MAPK. The PRLR contains no intrinsic tyrosine kinase cytoplasmic domain but associates with a cytoplasmic tyrosine kinase, JAK2. PRLR mainly serves as the receptor for the pituitary hormone prolactin (PRL), a secreted hormone that affects reproduction and homeostasis in vertebrates. PRLR can be regulated by an interplay of two different mechanisms, PRL or ovarian steroid hormones independently or in combination in a tissue-specific manner. The role of the hormone prolactin (PRL) in the pathogenesis of breast cancer is mediated by its cognate receptor (PRLR). Ubiquitin-dependent degradation of the PRLR that negatively regulates PRL signaling is triggered by PRL-mediated phosphorylation of PRLR on Ser349 followed by the recruitment of the beta-transducin repeats-containing protein (beta- TrCP) ubiquitin-protein isopeptide ligase. which altered PRLR stability may directly influence the pathogenesis of breast cancer.
UniProt P05710-1
Pathways JAK-STAT Signaling

Application Details

Product Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Handling References for anti-Prolactin Receptor Antibody (ABIN2001649) Images back to top
Application Notes ELISA ELISA: 0.5-1 µg/mL This antibody can be used at 0.5-1 µg/mL with the appropriate secondary reagents to detect Rat PRLR. The detection limit for Rat PRLR is approximately 0.039 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Application Details References for anti-Prolactin Receptor Antibody (ABIN2001649) Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months

References for anti-Prolactin Receptor Antibody (ABIN2001649)

Product Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Application Details Handling Images back to top
Background publications

Goffin, Binart, Clément-Lacroix, Bouchard, Bole-Feysot, Edery, Lucas, Touraine, Pezet, Maaskant, Pichard, Helloco, Baran, Favre, Bernichtein, Allamando, Ormandy, Kelly: "From the molecular biology of prolactin and its receptor to the lessons learned from knockout mice models." in: Genetic analysis : biomolecular engineering, Vol. 15, Issue 3-5, pp. 189-201, 2000