You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human Serotonin Receptor 1A antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Serotonin Receptor 1A Antibody (supplied by: Log in to see )

Antigen
Serotonin Receptor 1A (HTR1A) Antibodies
  • 5-HT-1A
  • 5-HT-dro2A
  • 5-HT1A
  • 5-Ht1a
  • 5-HT1ADro
  • 5-HT[1A]Dro
  • 5-HT[[1ADro]]
  • 5-HT[[1A]]
  • 5-HT[[1A]]DRO
  • 5HT-dro2A
  • 5HT-drp[[2A]]
  • 5HT-R2A
  • 5HT1A
  • 5HT1a
  • 5ht1a
  • 5htdro2a
  • 5htr1a
  • 5HT[[1ADro]]
  • ADRB2RL1
  • adrb2rl1
  • ADRBRL1
  • adrbrl1
  • CG16720
  • d5-HT1A
  • Dm5HTdro2A
  • Dmel\\CG16720
  • DRO2A
  • G-21
  • Gpcr18
  • HTR1A
  • htr1a
  • Htr1a
  • htr1a-A
  • PFMCD
  • RAT5HT1A
Epitope
AA 404-422, C-Term
5
4
4
2
1
1
1
Reactivity
Human, Rat (Rattus)
24
18
9
Host
Rabbit
19
13
1
Clonality
Polyclonal
Conjugate
This Serotonin Receptor 1A antibody is un-conjugated
2
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
32
23
3
2
2
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN3044241
$ 200.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN2439036 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0008982679 ABIN2140313 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
0.0008982679 ABIN3032544 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal

Similar anti-Serotonin Receptor 1A Antibodies

Application / Reactivity Rat (Rattus) Human
ELISA 7 Antibodies 14 Antibodies
Immunohistochemistry (IHC) 1 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antibodies 4 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 10 Antibodies

General

Antigen Serotonin Receptor 1A (HTR1A) Antibodies
Epitope AA 404-422, C-Term
(5), (4), (4), (2), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(24), (18), (9)
Host Rabbit
(19), (13), (1)
Clonality
Polyclonal
Conjugate This Serotonin Receptor 1A antibody is un-conjugated
(2), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(32), (23), (3), (2), (2)
Supplier Log in to see

Product Details anti-Serotonin Receptor 1A Antibody

Target Details Serotonin Receptor 1A Application Details Handling Images
Sequence NKDFQNAFKK IIKCKFCRQ
Cross-Reactivity (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Characteristics Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 1A(HTR1A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: 5-hydroxytryptamine(serotonin) receptor 1A, G protein-coupled
Protein Name: 5-hydroxytryptamine receptor 1A(5-HT-1A/5-HT1A)
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT1A Receptor(404-422aa NKDFQNAFKKIIKCKFCRQ), different from the related rat and mouse sequences by one amino acid.
Isotype IgG

Target Details Serotonin Receptor 1A

Product Details anti-Serotonin Receptor 1A Antibody Application Details Handling Images back to top
Antigen
Alternative Name HTR1A (HTR1A Antibody Abstract)
Background HTR1A(5-HYDROXYTRYPTAMINE RECEPTOR 1A), also called SEROTONIN 5-HT-1A RECEPTOR or BETA-2-ADRENERGIC RECEPTOR-LIKE PROTEIN G-21, is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin. It is a G protein-coupled receptor(GPCR) that is coupled to Gi/Go and mediates inhibitory neurotransmission. HTR1A denotes the human gene encoding for the receptor.The HTR1A gene is located at 5q12.3. The decreases in 5-HT-1A receptor densities correlated with decreased glucose utilization as measured by PET scan. Activation of 5-HT-1A receptors has been demonstrated to impair cognition, learning, and memory by inhibiting the release of glutamate and acetylcholine in various areas of the brain. 5-HT-1A receptors in the dorsal raphe nucleus are co-localized with neurokinin 1(NK1) receptors and have been shown to inhibit the release of substance P, their endogenous ligand.
UniProt P08908
Pathways JAK-STAT Signaling

Application Details

Product Details anti-Serotonin Receptor 1A Antibody Target Details Serotonin Receptor 1A Handling Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-Serotonin Receptor 1A Antibody Target Details Serotonin Receptor 1A Application Details Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Thimerosal (Merthiolate),Sodium azide a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C,4 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Expiry Date 12 months

Images

Product Details anti-Serotonin Receptor 1A Antibody Target Details Serotonin Receptor 1A Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Serotonin Receptor 1A antibody (HTR1A) (AA 404-422) (ABIN3044241) Anti-5HT1A Receptor antibody, IHC(P) IHC(P): Rat Brain Tissue
Western Blotting (WB) image for anti-Serotonin Receptor 1A antibody (HTR1A) (AA 404-422) (ABIN3044241) Anti-5HT1A Receptor antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2...