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|Application / Reactivity||Rat (Rattus)||Mouse (Murine)|
|Dot Blot (DB)||1 Antibodies||1 Antibodies|
|ELISA||12 Antibodies||20 Antibodies|
|Enzyme Immunoassay (EIA)||3 Antibodies||2 Antibodies|
|Immunocytochemistry (ICC)||3 Antibodies||2 Antibodies|
|Immunoelectron Microscopy (IEM)||1 Antibodies||1 Antibodies|
|Immunofluorescence (IF)||5 Antibodies||3 Antibodies|
|Immunohistochemistry (IHC)||10 Antibodies||6 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||7 Antibodies||5 Antibodies|
|Immunoprecipitation (IP)||3 Antibodies||3 Antibodies|
|Western Blotting (WB)||33 Antibodies|
|Antigen||Serotonin Receptor 1A (HTR1A) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This Serotonin Receptor 1A antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-Serotonin Receptor 1A AntibodyTarget Details Serotonin Receptor 1A Application Details Handling Images
|Specificity||This antibody detects endogenous levels of SR-1A protein. (region surrounding Phe321)|
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
|Purity||> 90 % pure SDS-PAGE|
Target Details Serotonin Receptor 1AProduct Details anti-Serotonin Receptor 1A Antibody Application Details Handling Images back to top
|Background||The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. β-adrenergic bound to adrenaline activates adenylyl cyclase, while α2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the α2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories,designated SR-1-7 (5HT1-7). Subtypes within the SR-1 group include SR-1A,-1B, -1D, -1E and -1F.Synonyms: 5-HT-1A, 5-HT1A, 5-hydroxytryptamine receptor 1A, ADRB2RL1, ADRBRL1|
|Molecular Weight||approx. 46 kDa|
Application DetailsProduct Details anti-Serotonin Receptor 1A Antibody Target Details Serotonin Receptor 1A Handling Images back to top
ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Serotonin Receptor 1A Antibody Target Details Serotonin Receptor 1A Application Details Images back to top
|Buffer||Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
ImagesProduct Details anti-Serotonin Receptor 1A Antibody Target Details Serotonin Receptor 1A Application Details Handling back to top