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|Antigen||Serotonin Receptor 2B (HTR2B) Antibodies|
|Epitope||AA 446-478, C-Term Alternatives|
|Reactivity||Human, Rat (Rattus) Alternatives|
Western Blotting (WB)
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Product Details anti-Serotonin Receptor 2B AntibodyTarget Details Serotonin Receptor 2B Application Details Handling Images
|Sequence||MRLRSSTIQS SSIILLDTLL LTENEGDKTE EQ|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 2B(HTR2B) detection. Tested with WB in Human,Rat.
Gene Name: 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
Protein Name: 5-hydroxytryptamine receptor 2B
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2B Receptor (446-478aa MRLRSSTIQSSSIILLDTLLLTENEGDKTEEQ V), different from the related mouse sequence by six amino acids, and from the related rat sequence by nine amino acids.|
Target Details Serotonin Receptor 2BProduct Details anti-Serotonin Receptor 2B Antibody Application Details Handling Images back to top
|Alternative Name||HTR2B (HTR2B Antibody Abstract)|
|Background||5HT2B Receptor is known as HTR2B. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.|
Application DetailsProduct Details anti-Serotonin Receptor 2B Antibody Target Details Serotonin Receptor 2B Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Serotonin Receptor 2B Antibody Target Details Serotonin Receptor 2B Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||-20 °C,4 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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