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Browse our anti-SOCS1 (SOCS1) Antibodies

Full name:
anti-Suppressor of Cytokine Signaling 1 Antibodies (SOCS1)
On are 172 Suppressor of Cytokine Signaling 1 (SOCS1) Antibodies from 28 different suppliers available. Additionally we are shipping SOCS1 Kits (23) and SOCS1 Proteins (13) and many more products for this protein. A total of 222 SOCS1 products are currently listed.
CIS1, Cish1, Cish7, JAB, LOC100228306, Socs-1, SOCS1, socs1b, SSI-1, SSI1, TIP3, zgc:91868
list all antibodies Gene Name GeneID UniProt
SOCS1 8651 O15524
SOCS1 12703 O35716
SOCS1 252971 Q9QX78

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anti-Human SOCS1 Antibodies:

anti-Mouse (Murine) SOCS1 Antibodies:

anti-Rat (Rattus) SOCS1 Antibodies:

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Top referenced anti-SOCS1 Antibodies

  1. Human Polyclonal SOCS1 Primary Antibody for WB - ABIN252586 : Prêle, Woodward, Bisley, Keith-Magee, Nicholson, Hart: SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 4 references for ABIN252586

  2. Human Polyclonal SOCS1 Primary Antibody for FACS, IF - ABIN652738 : Starr, Willson, Viney, Murray, Rayner, Jenkins, Gonda, Alexander, Metcalf, Nicola, Hilton: A family of cytokine-inducible inhibitors of signalling. in Nature 1997 (PubMed)
    Show all 2 references for ABIN652738

  3. Human Polyclonal SOCS1 Primary Antibody for EIA, WB - ABIN453835 : Minamoto, Ikegame, Ueno, Narazaki, Naka, Yamamoto, Matsumoto, Saito, Hosoe, Kishimoto: Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3. in Biochemical and biophysical research communications 1997 (PubMed)
    Show all 2 references for ABIN453835

  4. Human Polyclonal SOCS1 Primary Antibody for ELISA, IHC (p) - ABIN451850 : Nazmi, Mukherjee, Kundu, Dutta, Mahadevan, Shankar, Basu: TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection. in Neurobiology of disease 2014 (PubMed)

  5. Human Polyclonal SOCS1 Primary Antibody for EIA, WB - ABIN500790 : Rakesh, Agrawal: Controlling cytokine signaling by constitutive inhibitors. in Biochemical pharmacology 2005 (PubMed)

  6. Cow (Bovine) Polyclonal SOCS1 Primary Antibody for IHC, WB - ABIN2777164 : Melzner, Weniger, Bucur, Brüderlein, Dorsch, Hasel, Leithäuser, Ritz, Dyer, Barth, Möller: Biallelic deletion within 16p13.13 including SOCS-1 in Karpas1106P mediastinal B-cell lymphoma line is associated with delayed degradation of JAK2 protein. in International journal of cancer. Journal international du cancer 2006 (PubMed)

More Antibodies against SOCS1 Interaction Partners

Zebrafish Suppressor of Cytokine Signaling 1 (SOCS1) interaction partners

  1. Socs1a transgenic zebrafish have liver steatosis and insulin (show INS Antibodies) resistance.

  2. Studies demonstrate a conserved role for SOCS1 in T cell development and suggest a novel T cell-independent function in embryonic myelopoiesis mediated, at least in part, via its effects on receptors using the Jak2 (show JAK2 Antibodies)-Stat5 (show STAT5B Antibodies) pathway.

  3. in homozygotes, GH signaling is reduced by the action of the SOCS1 and SOCS3 (show SOCS3 Antibodies) proteins.

Rhesus Monkey Suppressor of Cytokine Signaling 1 (SOCS1) interaction partners

  1. SOCS1 alleviates RhTRIM5alpha-mediated regulation in the late phase of HIV-1 life cycle probably due to the destabilization of RhTRIM5alpha.

Rainbow Trout (Oncorhynchus mykiss) Suppressor of Cytokine Signaling 1 (SOCS1) interaction partners

  1. The upregulation of SOCS-1 and SOCS-2 (show SOCS2 Antibodies) by cortisol may be playing a key role in suppressing cytokine signaling and the associated inflammatory response.

Human Suppressor of Cytokine Signaling 1 (SOCS1) interaction partners

  1. this study shows that IL-7 (show IL7 Antibodies) induces the expression of SOCS1 through the JAK (show JAK3 Antibodies)/STAT-5 (show STAT5A Antibodies) pathway

  2. SOCS1 silencing can inhibit proliferation and induce apoptosis of MV3 and A357 melanoma cells in vivo and in vitro by inhibiting extracellular signal-regulated kinase and janus kinase signal transduction and activators of transcription signaling pathways.

  3. SOCS1 may promote apoptosis of intestinal epithelial cells at least partly through mediating p53 (show TP53 Antibodies) signaling.

  4. The results revealed that although the expression levels of SOCS1, SOCS3 (show SOCS3 Antibodies) and, in particular, pSHP2, tend to decrease in the four types of astrocytomas, PIAS3 (show PIAS3 Antibodies) downregulation is more negatively correlated with STAT3 (show STAT3 Antibodies) activation in the stepwise progress of astrocytomas and would indicate an unfavorable outcome.

  5. findings provide novel insight into how dysregulated expression of SOCS (show CISH Antibodies) increases IL-4 (show IL4 Antibodies) responses in allergic monocytes, and this may represent a new therapeutic avenue for managing allergic disease.

  6. Overexpression of SOCS1 has a potent antitumor effect against ESCC.

  7. IL-4 (show IL4 Antibodies) signaling plays a crucial role in the regulatory functions of SOCS1 in apoptosis and inflammation in human osteoarthritic chondrocytes. These findings provide a potential therapeutic target for the clinical treatment of osteoarthritis (OA)

  8. We demonstrated that VDR (show CYP27B1 Antibodies)/miRNA155-modulated SOCS1 expression is decreased in PBC (show DLAT Antibodies) which may lead to insufficient negative regulation of cytokine signaling. These findings suggest that the decreased VDR (show CYP27B1 Antibodies) signaling in PBC (show DLAT Antibodies) could be of importance in the pathogenesis of PBC (show DLAT Antibodies).

  9. Through promoter hypermethylation, the SOCS-1 gene was severely down-regulated in the colorectal cancer tissue samples.

  10. Reduced SOCS1 protein levels in systemic lupus erythematosus patients are correlated with enhanced STAT1 (show STAT1 Antibodies) activation.

Mouse (Murine) Suppressor of Cytokine Signaling 1 (SOCS1) interaction partners

  1. this study shows that genetic modification of dendritic cells with SOCS1 affects their activation and maturation, inhibits T-cell proliferation and induces hypo-responsiveness, and prolongs islet allograft survival

  2. SOCS1 may promote apoptosis of intestinal epithelial cells at least partly through mediating p53 (show TP53 Antibodies) signaling.

  3. Kdm5a (show KDM5A Antibodies) associates with p50 (show LSP1 Antibodies) and binds to the Socs1 promoter region in resting natural killer cells.

  4. The miR (show MLXIP Antibodies)-155 inhibitor relieves liver injury by enhancing the expression of SOCS1 and inactivating JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling.

  5. NOS1 (show NOS1 Antibodies)-derived nitric oxide promotes NF-kappaB (show NFKB1 Antibodies) transcriptional activity through inhibition of Socs1.Cys147 and Cys179 are essential for SOCS1 nitrosation and proteasomal degradation.

  6. mir (show MLXIP Antibodies)-155 deficiency attenuates liver ischemia-reperfusion injury through upregulation of SOCS1, which is associated with promotion of M2 macrophage and inhibition of Th17 differentiation

  7. Findings indicate that SOCS1 mediates its tumor suppressor functions, at least partly, by binding to MET and interfering with downstream signaling pathways as well as by promoting the turnover of the activated MET receptor.

  8. increased expression of SOCS-1 in the lungs of mice significantly protects against hyperoxic lung injury.

  9. Overexpression of SOCS1 in transgenic rat eyes attenuated ocular HSV-1 infection

  10. Axl (show AXL Antibodies) promotes STAT1 (show STAT1 Antibodies) signaling via inhibition of SOCS1 in activated smooth muscle cells in vein graft remodeling.

SOCS1 Antigen Profile

Antigen Summary

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Alternative names and synonyms associated with SOCS1

  • suppressor of cytokine signaling 1a (socs1a) antibody
  • suppressor of cytokine signaling 1 (socs1) antibody
  • suppressor of cytokine signaling 1 (SOCS1) antibody
  • suppressor of cytokine signaling 1 (LOC100228306) antibody
  • suppressor of cytokine signaling 1 (socs1-b) antibody
  • suppressor of cytokine signaling 1-like protein (socs1) antibody
  • suppressor of cytokine signaling 1 (Socs1) antibody
  • CIS1 antibody
  • Cish1 antibody
  • Cish7 antibody
  • JAB antibody
  • LOC100228306 antibody
  • Socs-1 antibody
  • SOCS1 antibody
  • socs1b antibody
  • SSI-1 antibody
  • SSI1 antibody
  • TIP3 antibody
  • zgc:91868 antibody

Protein level used designations for SOCS1

suppressor of cytokine signaling 1 , suppressor of cytokine signalling , suppressor of cytokine signaling 1b , suppressor of cytokine signaling 1-like protein , JAK binding protein , JAK-binding protein , STAT induced SH3 protein 1 , STAT-induced STAT inhibitor 1 , TIP-3 , Tec-interacting protein 3 , cytokine-inducible SH2 protein 1 , JAK2-binding protein , cytokine inducible SH2-containing protein 1 , cytokine inducible SH2-containing protein 7

445073 Danio rerio
496789 Xenopus (Silurana) tropicalis
711180 Macaca mulatta
737070 Pan troglodytes
100144374 Oryzias latipes
100228306 Taeniopygia guttata
100272210 Oncorhynchus mykiss
100294520 Xenopus laevis
100049621 Takifugu rubripes
8651 Homo sapiens
12703 Mus musculus
416630 Gallus gallus
490006 Canis lupus familiaris
252971 Rattus norvegicus
518795 Bos taurus
100307052 Sus scrofa
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