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anti-Human SOCS1 antibody for Immunohistochemistry (Frozen Sections)

Recommended SOCS1 Antibody (supplied by: Log in to see )

Antigen
Suppressor of Cytokine Signaling 1 (SOCS1) Antibodies
  • CIS1
  • cis1
  • CISH1
  • cish1
  • Cish1
  • Cish7
  • jab
  • JAB
  • LOC100228306
  • Socs-1
  • socs-1
  • SOCS-1
  • SOCS1
  • socs1
  • socs1b
  • SSI-1
  • ssi-1
  • SSI1
  • ssi1
  • TIP3
  • tip3
  • zgc:91868
Epitope
C-Term
59
27
13
5
4
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
151
66
55
8
8
4
2
2
1
Host
Rabbit
135
18
10
Clonality
Polyclonal
Conjugate
This SOCS1 antibody is un-conjugated
7
7
6
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
140
55
34
28
11
9
8
8
4
4
2
Supplier
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Catalog No. ABIN488052
$ 401.50
Plus shipping costs $45.00

Similar anti-SOCS1 Antibodies

Application / Reactivity Human
ELISA 55 Antibodies
Enzyme Immunoassay (EIA) 8 Antibodies
Flow Cytometry (FACS) 4 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 35 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 133 Antibodies

General

Antigen Suppressor of Cytokine Signaling 1 (SOCS1) Antibodies
Epitope C-Term
(59), (27), (13), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(151), (66), (55), (8), (8), (4), (2), (2), (1)
Host Rabbit
(135), (18), (10)
Clonality
Polyclonal
Conjugate This SOCS1 antibody is un-conjugated
(7), (7), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(140), (55), (34), (28), (11), (9), (8), (8), (4), (4), (2)
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Product Details anti-SOCS1 Antibody

Target Details SOCS1 Application Details Handling Images
Specificity Recognizes cytokine inducible SH2-containing protein CIS.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Antigen-Affinity Chromatography.
Immunogen Synthetic peptide contain a sequence corresponding to a region within amino acids 196 and 208 of CIS

Target Details SOCS1

Product Details anti-SOCS1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CIS1 (SOCS1 Antibody Abstract)
Background The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: CIS-1, CISH, Cytokine-inducible SH2-containing protein, G18, Suppressor of cytokine signaling
Gene ID 1154, 9606
UniProt Q9NSE2
Pathways JAK-STAT Signaling, Interferon-gamma Pathway, TLR Signaling

Application Details

Product Details anti-SOCS1 Antibody Target Details SOCS1 Handling Images back to top
Application Notes This antibody is suitable for use in Immunofluorescence/Immunocytochemistry, Westernblotting and Immunohistochemistry. Recommended Dilutions: Western blotting: 1/500-1/3000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin Sections: 1/100-1/500. Positive Controls: HeLaS3/Molt-4.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-SOCS1 Antibody Target Details SOCS1 Application Details Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer 1 x PBS ( pH 7) containing 1 % BSA, 20 % Glycerol and 0.01 % Thimerosal as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody undiluted (in aliquots) at -20 °C.

Images

Product Details anti-SOCS1 Antibody Target Details SOCS1 Application Details Handling back to top
Supplier Images
Immunofluorescence (IF) image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (C-Term) (ABIN488052) Figure 3. Immunofluorescence analysis of paraformaldehyde-fixed A431...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (C-Term) (ABIN488052) Figure 2. Immunohistochemical analysis of paraffin-embedded Lung CA,...
Western Blotting (WB) image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (C-Term) (ABIN488052) Figure 1. CIS antibody staining of HeLaS3 (A) whole cell lysate (30 ...