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anti-Mouse (Murine) SOCS1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended SOCS1 Antibody (supplied by: Log in to see )

Antigen
Suppressor of Cytokine Signaling 1 (SOCS1) Antibodies
  • CIS1
  • cis1
  • CISH1
  • cish1
  • Cish1
  • Cish7
  • jab
  • JAB
  • LOC100228306
  • Socs-1
  • socs-1
  • SOCS-1
  • SOCS1
  • socs1
  • socs1b
  • SSI-1
  • ssi-1
  • SSI1
  • ssi1
  • TIP3
  • tip3
  • zgc:91868
Epitope
AA 160-211
60
27
12
5
4
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
151
65
54
8
8
4
2
2
1
Host
Rabbit
135
18
10
Clonality
Polyclonal
Conjugate
This SOCS1 antibody is un-conjugated
7
7
6
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
140
55
34
28
10
10
8
8
4
4
2
1
Supplier
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Catalog No. ABIN725135
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008812635 ABIN2806550 IF (p) Alexa Fluor 594 Rabbit IgG AA 160-211 Log in to see Polyclonal
0.0008812635 ABIN725138 IF (p) Cy3 Rabbit IgG AA 160-211 Log in to see Polyclonal
0.0008812635 ABIN725140 IF (p) Cy5.5 Rabbit IgG AA 160-211 Log in to see Polyclonal
0.0008812635 ABIN725139 IF (p) Cy5 Rabbit IgG AA 160-211 Log in to see Polyclonal
0.0008812635 ABIN725141 IF (p) Cy7 Rabbit IgG AA 160-211 Log in to see Polyclonal
0.0008812635 ABIN725142 IF (p) FITC Rabbit IgG AA 160-211 Log in to see Polyclonal
0.0008812635 ABIN916016 IF (p) Alexa Fluor 350 Rabbit IgG AA 160-211 Log in to see Polyclonal
0.0008812635 ABIN916015 IF (p) Alexa Fluor 488 Rabbit IgG AA 160-211 Log in to see Polyclonal
0.0008812635 ABIN916018 IF (p) Alexa Fluor 647 Rabbit IgG AA 160-211 Log in to see Polyclonal
0.0008812635 ABIN916019 IF (p) Alexa Fluor 555 Rabbit IgG AA 160-211 Log in to see Polyclonal

Similar anti-SOCS1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 15 Antibodies 20 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies 5 Antibodies
Flow Cytometry (FACS) 1 Antibodies 2 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 1 Antibodies
Immunofluorescence (IF) 4 Antibodies 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 12 Antibodies 15 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 43 Antibodies

General

Antigen Suppressor of Cytokine Signaling 1 (SOCS1) Antibodies
Epitope AA 160-211
(60), (27), (12), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(151), (65), (54), (8), (8), (4), (2), (2), (1)
Host Rabbit
(135), (18), (10)
Clonality
Polyclonal
Conjugate This SOCS1 antibody is un-conjugated
(7), (7), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(140), (55), (34), (28), (10), (10), (8), (8), (4), (4), (2), (1)
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Product Details anti-SOCS1 Antibody

Target Details SOCS1 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Socs 1
Isotype IgG

Target Details SOCS1

Product Details anti-SOCS1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SOCS1 (SOCS1 Antibody Abstract)
Background

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity. Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF). Regulates interferon-gamma mediated sensory neuron survival (By similarity). Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize JAK2. SOCS1 appears to be a negative regulator in IGF1R signaling pathway.

Subcellular location: Nucleus


Synonyms: JAB, CIS1, SSI1, TIP3, CISH1, SSI-1, SOCS-1, Suppressor of cytokine signaling 1, JAK-binding protein, STAT-induced STAT inhibitor 1, Tec-interacting protein 3, TIP-3, SOCS1
Gene ID 8651
UniProt O15524
Research Area Chromatin and Nuclear Signaling, Signaling, Cytokines
Pathways JAK-STAT Signaling, Interferon-gamma Pathway, TLR Signaling

Application Details

Product Details anti-SOCS1 Antibody Target Details SOCS1 Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-SOCS1 Antibody Target Details SOCS1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-SOCS1 Antibody Target Details SOCS1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (AA 160-211) (ABIN725135) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-SOCS 1 Polyc...
Immunohistochemistry (IHC) image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (AA 160-211) (ABIN725135) Formalin-fixed and paraffin embedded human colon cancer labeled with Anti-Socs1Polycl...